Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.67
  2. 405194Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
  3. 419895Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 419896Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 420349Family d.153.1.5: (Glycosyl)asparaginase [56261] (1 protein)
  6. 420350Protein Glycosylasparaginase (aspartylglucosaminidase, AGA) [56262] (3 species)
    the precursor chain is cleaved onto 2 fragments by autoproteolysis
  7. 420373Species Human (Homo sapiens) [TaxId:9606] [56263] (2 PDB entries)

PDB entries in Species: Human (Homo sapiens):

  1. Domain(s) for 1apy:
    1. 420374Domain d1apy.1: 1apy A:,B: [42004]
    2. 420375Domain d1apy.2: 1apy C:,D: [42005]
      complexed with man, nag
  2. Domain(s) for 1apz:
    1. 420376Domain d1apz.1: 1apz A:,B: [42006]
    2. 420377Domain d1apz.2: 1apz C:,D: [42007]
      complexed with man, nag

More info for Species Human (Homo sapiens) [TaxId:9606] from d.153.1.5 Glycosylasparaginase (aspartylglucosaminidase, AGA)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.153.1.5 Glycosylasparaginase (aspartylglucosaminidase, AGA):