Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies) 4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing |
Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) N-terminal residue provides two catalytic groups, nucleophile and proton donor |
Family d.153.1.5: (Glycosyl)asparaginase [56261] (2 proteins) automatically mapped to Pfam PF01112 |
Protein Glycosylasparaginase (aspartylglucosaminidase, AGA) [56262] (5 species) the precursor chain is cleaved onto 2 fragments by autoproteolysis |
Species Human (Homo sapiens) [TaxId:9606] [56263] (2 PDB entries) |
Domain d1apy.1: 1apy A:,B: [42004] complexed with nag |
Domain d1apy.2: 1apy C:,D: [42005] complexed with nag |
Domain d1apz.1: 1apz A:,B: [42006] complexed with asp, nag |
Domain d1apz.2: 1apz C:,D: [42007] complexed with asp, nag |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.153.1.5 Glycosylasparaginase (aspartylglucosaminidase, AGA):