Lineage for Protein: Glycosylasparaginase (aspartylglucosaminidase, AGA)

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 263343Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 263344Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 263704Family d.153.1.5: (Glycosyl)asparaginase [56261] (1 protein)
  6. 263705Protein Glycosylasparaginase (aspartylglucosaminidase, AGA) [56262] (2 species)
    the precursor chain is cleaved onto 2 fragments by autoproteolysis

Species:

  1. 263706Flavobacterium meningosepticum [TaxId:238] [56264] (6 PDB entries)
    1. Domains for 1ayy:
      1. 263709Domain d1ayy.1: 1ayy A:,B: [42016]
      2. 263710Domain d1ayy.2: 1ayy C:,D: [42017]
    2. Domains for 2gac:
      1. 263707Domain d2gac.1: 2gac A:,B: [42012]
      2. 263708Domain d2gac.2: 2gac C:,D: [42013]
        mutant
    3. Domains for 2gaw:
      1. 263711Domain d2gaw.1: 2gaw A:,B: [42018]
      2. 263712Domain d2gaw.2: 2gaw C:,D: [42019]
    4. Domains for 9gaa:
      1. 263717Domain d9gaaa_: 9gaa A: [42014]
      2. 263718Domain d9gaac_: 9gaa C: [42015]
        Precursor of the T152A mutant
    5. Domains for 9gac:
      1. 263715Domain d9gaca_: 9gac A: [42010]
      2. 263716Domain d9gacc_: 9gac C: [42011]
        Precursor of the T152C mutant
    6. Domains for 9gaf:
      1. 263713Domain d9gafa_: 9gaf A: [42008]
      2. 263714Domain d9gafc_: 9gaf C: [42009]
        Precursor of the W11F mutant
  2. 263719Human (Homo sapiens) [TaxId:9606] [56263] (2 PDB entries)
    1. Domains for 1apy:
      1. 263720Domain d1apy.1: 1apy A:,B: [42004]
      2. 263721Domain d1apy.2: 1apy C:,D: [42005]
        complexed with man, nag
    2. Domains for 1apz:
      1. 263722Domain d1apz.1: 1apz A:,B: [42006]
      2. 263723Domain d1apz.2: 1apz C:,D: [42007]
        complexed with man, nag

More info for Protein Glycosylasparaginase (aspartylglucosaminidase, AGA) from d.153.1.5: (Glycosyl)asparaginase

Timeline for Protein Glycosylasparaginase (aspartylglucosaminidase, AGA) from d.153.1.5: (Glycosyl)asparaginase: