Lineage for Family d.153.1.5: (Glycosyl)asparaginase

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1934404Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 1934405Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 1937328Family d.153.1.5: (Glycosyl)asparaginase [56261] (2 proteins)
    automatically mapped to Pfam PF01112

Proteins:

  1. 1937329Glycosylasparaginase (aspartylglucosaminidase, AGA) [56262] (4 species)
    the precursor chain is cleaved onto 2 fragments by autoproteolysis
    1. 1937330Species Elizabethkingia miricola [TaxId:172045] [261921] (1 PDB entry)
    2. 1937333Species Escherichia coli [TaxId:562] [103315] (3 PDB entries)
      Uniprot P37595
      isoaspartyl peptidase with L-asparaginase activity
      putative L-asparaginase YbiK
    3. 1937340Species Flavobacterium meningosepticum [TaxId:238] [56264] (8 PDB entries)
    4. 1937357Species Human (Homo sapiens) [TaxId:9606] [56263] (2 PDB entries)
  2. 1937362automated matches [191198] (1 species)
    not a true protein

More info for Family d.153.1.5: (Glycosyl)asparaginase

Timeline for Family d.153.1.5: (Glycosyl)asparaginase: