SCOPe 2.08: Family d.153.1.5: (Glycosyl)asparaginase

Lineage for Family d.153.1.5: (Glycosyl)asparaginase

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.5: (Glycosyl)asparaginase [56261] (2 proteins)
   automatically mapped to Pfam PF01112

Proteins:

1. Glycosylasparaginase (aspartylglucosaminidase, AGA) [56262] (5 species)
   the precursor chain is cleaved onto 2 fragments by autoproteolysis

   1. Species Elizabethkingia meningoseptica [TaxId:238] [334312] (1 PDB entry)

   2. Species Elizabethkingia miricola [TaxId:172045] [261921] (1 PDB entry)

   3. Species Escherichia coli [TaxId:562] [103315] (3 PDB entries)
      Uniprot P37595
      isoaspartyl peptidase with L-asparaginase activity
      putative L-asparaginase YbiK

   4. Species Flavobacterium meningosepticum [TaxId:238] [56264] (8 PDB entries)

   5. Species Human (Homo sapiens) [TaxId:9606] [56263] (2 PDB entries)

2. automated matches [191198] (1 species)
   not a true protein

   • Species Flavobacterium meningosepticum [TaxId:238] [189513] (1 PDB entry)

More info for Family d.153.1.5: (Glycosyl)asparaginase

Timeline for Family d.153.1.5: (Glycosyl)asparaginase:

• Family d.153.1.5: (Glycosyl)asparaginase first appeared (with stable ids) in SCOP 1.55
  
• Family d.153.1.5: (Glycosyl)asparaginase appears in SCOPe 2.07