Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2224590Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2224591Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2224775Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

Proteins:

  1. 2224776HslV (ClpQ) protease [56258] (4 species)
    dodecameric prokaryotic homologue of proteasome
    1. 2224777Species Bacillus subtilis [TaxId:1423] [160845] (2 PDB entries)
      Uniprot P39070 2-181
    2. 2224792Species Escherichia coli [TaxId:562] [56259] (8 PDB entries)
    3. 2224840Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    4. 2224883Species Thermotoga maritima [TaxId:2336] [90045] (1 PDB entry)
  2. 2224887Proteasome alpha subunit (non-catalytic) [56255] (8 species)
    contains an extension to the common fold at the N-terminus
    1. 2224888Species Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 2224903Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (193 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2226213Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256264] (12 PDB entries)
    4. 2226285Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    5. 2226300Species Human (Homo sapiens) [TaxId:9606] [311422] (8 PDB entries)
    6. 2226351Species Mouse (Mus musculus) [TaxId:10090] [195927] (2 PDB entries)
    7. 2226356Species Rhodococcus erythropolis [TaxId:1833] [103314] (3 PDB entries)
    8. 2226378Species Thermoplasma acidophilum [TaxId:2303] [56256] (3 PDB entries)
  3. 2226421Proteasome beta subunit (catalytic) [56252] (6 species)
    1. 2226422Species Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 2226430Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (174 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2228252Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    4. 2228267Species Human (Homo sapiens) [TaxId:9606] [311421] (8 PDB entries)
    5. 2228315Species Rhodococcus erythropolis [TaxId:1833] [103313] (3 PDB entries)
    6. 2228337Species Thermoplasma acidophilum [TaxId:2303] [56253] (5 PDB entries)
  4. 2228394automated matches [190144] (11 species)
    not a true protein
    1. 2228395Species Bacillus anthracis [TaxId:198094] [189742] (1 PDB entry)
    2. 2228402Species Bacillus subtilis [TaxId:1423] [187296] (1 PDB entry)
    3. 2228415Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187078] (41 PDB entries)
    4. 2228665Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189752] (157 PDB entries)
    5. 2229886Species Escherichia coli [311130] (1 PDB entry)
    6. 2229891Species Escherichia coli [TaxId:562] [326970] (1 PDB entry)
    7. 2229896Species Human (Homo sapiens) [TaxId:9606] [311423] (8 PDB entries)
    8. 2229962Species Mouse (Mus musculus) [TaxId:10090] [195917] (3 PDB entries)
    9. 2230008Species Mycobacterium tuberculosis [TaxId:1773] [187707] (14 PDB entries)
    10. 2230393Species Mycobacterium tuberculosis [TaxId:419947] [328158] (1 PDB entry)
    11. 2230420Species Thermoplasma acidophilum [TaxId:2303] [186869] (7 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: