SCOPe 2.07: Family d.153.1.2: Penicillin acylase, catalytic domain

Lineage for Family d.153.1.2: Penicillin acylase, catalytic domain

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.2: Penicillin acylase, catalytic domain [56244] (3 proteins)

Proteins:

1. Cephalosporin acylase [64425] (2 species)

   1. Species Brevundimonas diminuta [TaxId:293] [64426] (4 PDB entries)

   2. Species Pseudomonas sp., glutarylamidase [TaxId:306] [69835] (5 PDB entries)

2. Penicillin acylase [56245] (2 species)
   also contains 2 all-alpha and a beta-barrel domains
   will be divided into domains in future release

   1. Species Escherichia coli [TaxId:562] [56246] (24 PDB entries)

   2. Species Providencia rettgeri [TaxId:587] [56247] (1 PDB entry)

3. automated matches [196663] (3 species)
   not a true protein

   1. Species Pseudomonas sp. [TaxId:269086] [311166] (1 PDB entry)

   2. Species Pseudomonas sp. [TaxId:306] [311215] (1 PDB entry)

   3. Species Pseudomonas sp. [TaxId:81841] [196664] (3 PDB entries)

More info for Family d.153.1.2: Penicillin acylase, catalytic domain

Timeline for Family d.153.1.2: Penicillin acylase, catalytic domain:

• Family d.153.1.2: Penicillin acylase, catalytic domain first appeared (with stable ids) in SCOP 1.55
  
• Family d.153.1.2: Penicillin acylase, catalytic domain appears in SCOPe 2.06
  
• Family d.153.1.2: Penicillin acylase, catalytic domain appears in the current release, SCOPe 2.08