SCOP 1.73: Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases)

Lineage for Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (6 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

Families:

1. d.153.1.1: Class II glutamine amidotransferases [56236] (6 proteins)
   has slightly different topology than other families do

2. d.153.1.2: Penicillin acylase, catalytic domain [56244] (2 proteins)

3. d.153.1.3: Penicillin V acylase [56248] (1 protein)

4. d.153.1.4: Proteasome subunits [56251] (3 proteins)

5. d.153.1.5: (Glycosyl)asparaginase [56261] (1 protein)

6. d.153.1.6: Gamma-glutamyltranspeptidase-like [143906] (3 proteins)
   Pfam PF01019

More info for Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases)

Timeline for Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases):

• Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) first appeared (with stable ids) in SCOP 1.55
  
• Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) appears in SCOP 1.71
  
• Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) appears in SCOP 1.75
  
• Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) appears in the current release, SCOPe 2.08