Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain [56171] (2 proteins) |
Protein Phoshoinositide 3-kinase (PI3K), catalytic domain [56172] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [56174] (78 PDB entries) |
Domain d1e8ya4: 1e8y A:726-1092 [41715] Other proteins in same PDB: d1e8ya1, d1e8ya2, d1e8ya3, d1e8ya5 |
Domain d1e8za4: 1e8z A:726-1092 [41716] Other proteins in same PDB: d1e8za1, d1e8za2, d1e8za3 complexed with stu |
Domain d1he8a4: 1he8 A:726-1084 [41717] Other proteins in same PDB: d1he8a1, d1he8a2, d1he8a3, d1he8b_ complexed with gnp, mg |
Domain d2a4za4: 2a4z A:726-1087 [203393] Other proteins in same PDB: d2a4za1, d2a4za2, d2a4za3 automated match to d1e8ya4 complexed with bym |
Domain d2a5ua4: 2a5u A:726-1092 [203397] Other proteins in same PDB: d2a5ua1, d2a5ua2, d2a5ua3 automated match to d1e8ya4 complexed with qyt |
Domain d2chwa4: 2chw A:726-1092 [203790] Other proteins in same PDB: d2chwa1, d2chwa2, d2chwa3 automated match to d1e8ya4 complexed with 039 |
Domain d2chxa4: 2chx A:726-1093 [203794] Other proteins in same PDB: d2chxa1, d2chxa2, d2chxa3 automated match to d1e8ya4 complexed with 090 |
Domain d2chza4: 2chz A:726-1093 [203798] Other proteins in same PDB: d2chza1, d2chza2, d2chza3 automated match to d1e8ya4 complexed with 093 |
Domain d2v4la4: 2v4l A:726-1093 [206206] Other proteins in same PDB: d2v4la1, d2v4la2, d2v4la3 automated match to d1e8ya4 complexed with abj |
Domain d3apca4: 3apc A:726-1093 [245175] Other proteins in same PDB: d3apca1, d3apca2, d3apca3 automated match to d1e7ua4 complexed with mmd, so4 |
Domain d3apda4: 3apd A:726-1093 [245179] Other proteins in same PDB: d3apda1, d3apda2, d3apda3 automated match to d1e7ua4 complexed with mmy, so4 |
Domain d3apfa4: 3apf A:726-1092 [245183] Other proteins in same PDB: d3apfa1, d3apfa2, d3apfa3 automated match to d1e7ua4 complexed with bmw, so4 |
Domain d3csfa4: 3csf A:726-1088 [245527] Other proteins in same PDB: d3csfa1, d3csfa2, d3csfa3 automated match to d1e7ua4 complexed with dw2 |
Domain d3enea4: 3ene A:726-1092 [245884] Other proteins in same PDB: d3enea1, d3enea2, d3enea3 automated match to d1e7ua4 complexed with npz |
Domain d3ihya1: 3ihy A:532-871 [344784] Other proteins in same PDB: d3ihya2 |
Domain d3l08a4: 3l08 A:726-1090 [247310] Other proteins in same PDB: d3l08a1, d3l08a2, d3l08a3 automated match to d1e7ua4 complexed with so4, zig |
Domain d3ml8a4: 3ml8 A:726-1093 [213321] Other proteins in same PDB: d3ml8a1, d3ml8a2, d3ml8a3 automated match to d1e8ya4 complexed with ml8 |
Domain d3ml9a4: 3ml9 A:726-1093 [213325] Other proteins in same PDB: d3ml9a1, d3ml9a2, d3ml9a3 automated match to d1e8ya4 complexed with ml9 |
Domain d3nzsa4: 3nzs A:726-1092 [248106] Other proteins in same PDB: d3nzsa1, d3nzsa2, d3nzsa3 automated match to d1e7ua4 complexed with nzs |
Domain d3nzua4: 3nzu A:726-1094 [248110] Other proteins in same PDB: d3nzua1, d3nzua2, d3nzua3 automated match to d1e7ua4 complexed with nzu |
Domain d3oawa4: 3oaw A:726-1093 [248157] Other proteins in same PDB: d3oawa1, d3oawa2, d3oawa3 automated match to d1e7ua4 complexed with oaw |
Domain d3prea4: 3pre A:726-1093 [248626] Other proteins in same PDB: d3prea1, d3prea2, d3prea3 automated match to d1e7ua4 complexed with 3re |
Domain d3prza4: 3prz A:726-1093 [248636] Other proteins in same PDB: d3prza1, d3prza2, d3prza3 automated match to d1e7ua4 complexed with 3rz |
Domain d3ps6a4: 3ps6 A:726-1093 [248643] Other proteins in same PDB: d3ps6a1, d3ps6a2, d3ps6a3 automated match to d1e7ua4 complexed with 3ps |
Domain d3qaqa4: 3qaq A:726-1088 [248829] Other proteins in same PDB: d3qaqa1, d3qaqa2, d3qaqa3 automated match to d1e7ua4 complexed with qaq, so4 |
Domain d3qara4: 3qar A:726-1092 [248833] Other proteins in same PDB: d3qara1, d3qara2, d3qara3 automated match to d1e7ua4 complexed with qar, so4 |
Domain d3qjza3: 3qjz A:726-1089 [248914] Other proteins in same PDB: d3qjza1, d3qjza2 automated match to d1e7ua4 complexed with qjz, so4 |
Domain d3qk0a4: 3qk0 A:726-1092 [248918] Other proteins in same PDB: d3qk0a1, d3qk0a2, d3qk0a3 automated match to d1e7ua4 complexed with qk0, so4 |
Domain d3s2aa4: 3s2a A:726-1088 [249288] Other proteins in same PDB: d3s2aa1, d3s2aa2, d3s2aa3 automated match to d1e7ua4 complexed with 2nq, so4 |
Domain d3tjpa4: 3tjp A:726-1093 [216845] Other proteins in same PDB: d3tjpa1, d3tjpa2, d3tjpa3 automated match to d1e8ya4 complexed with 13k, so4 |
Domain d4dk5a4: 4dk5 A:726-1088 [251471] Other proteins in same PDB: d4dk5a1, d4dk5a2, d4dk5a3 automated match to d1e7ua4 complexed with 0ko, so4 |
Domain d4f1sa4: 4f1s A:726-1091 [251866] Other proteins in same PDB: d4f1sa1, d4f1sa2, d4f1sa3 automated match to d1e7ua4 complexed with f1s, so4 |
Domain d4fhja4: 4fhj A:726-1092 [251973] Other proteins in same PDB: d4fhja1, d4fhja2, d4fhja3 automated match to d1e7ua4 complexed with 0tz, so4 |
Domain d4fhka4: 4fhk A:726-1092 [251977] Other proteins in same PDB: d4fhka1, d4fhka2, d4fhka3 automated match to d1e7ua4 complexed with 0u0, so4 |
Domain d4fjya4: 4fjy A:726-1088 [252014] Other proteins in same PDB: d4fjya1, d4fjya2, d4fjya3 automated match to d1e7ua4 complexed with fjy, so4 |
Domain d4fjza4: 4fjz A:726-1088 [252018] Other proteins in same PDB: d4fjza1, d4fjza2, d4fjza3 automated match to d1e7ua4 complexed with 4fj, so4 |
Domain d4flha4: 4flh A:726-1092 [252036] Other proteins in same PDB: d4flha1, d4flha2, d4flha3 automated match to d1e7ua4 complexed with 14k, so4 |
Domain d4fula4: 4ful A:726-1092 [221538] Other proteins in same PDB: d4fula1, d4fula2, d4fula3 automated match to d1e8ya4 complexed with 0vu |
Domain d4hvba4: 4hvb A:726-1090 [229092] Other proteins in same PDB: d4hvba1, d4hvba2, d4hvba3 automated match to d1e8ya4 complexed with 19p |
Domain d4kz0a4: 4kz0 A:726-1092 [224532] Other proteins in same PDB: d4kz0a1, d4kz0a2, d4kz0a3 automated match to d1e8ya4 complexed with 1uj, so4 |
Domain d4ps3a4: 4ps3 A:726-1092 [257536] Other proteins in same PDB: d4ps3a1, d4ps3a2, d4ps3a3 automated match to d1e8ya4 complexed with 2wh |
Domain d4ps7a4: 4ps7 A:726-1092 [257538] Other proteins in same PDB: d4ps7a1, d4ps7a2, d4ps7a3 automated match to d1e8ya4 complexed with 2wj |
Domain d4ps8a4: 4ps8 A:726-1092 [257542] Other proteins in same PDB: d4ps8a1, d4ps8a2, d4ps8a3 automated match to d1e8ya4 complexed with 2wk |
Domain d4wwna4: 4wwn A:726-1088 [262151] Other proteins in same PDB: d4wwna1, d4wwna2, d4wwna3 automated match to d1e7ua4 complexed with 3vc, so4 |
Domain d4wwoa4: 4wwo A:726-1090 [262153] Other proteins in same PDB: d4wwoa1, d4wwoa2, d4wwoa3 automated match to d1e7ua4 complexed with 3vd, so4 |
Domain d4wwpa4: 4wwp A:726-1090 [262145] Other proteins in same PDB: d4wwpa1, d4wwpa2, d4wwpa3 automated match to d1e7ua4 complexed with 3ve, gol, so4 |
Domain d4xx5a4: 4xx5 A:726-1092 [275720] Other proteins in same PDB: d4xx5a1, d4xx5a2, d4xx5a3 automated match to d1e8ya4 complexed with 43r |
Domain d4xz4a4: 4xz4 A:726-1092 [311746] Other proteins in same PDB: d4xz4a1, d4xz4a2, d4xz4a3 automated match to d1e8za4 complexed with 456 |
Domain d5edsa4: 5eds A:726-1088 [345602] Other proteins in same PDB: d5edsa1, d5edsa2, d5edsa3 automated match to d1he8a4 complexed with 5mt, so4 |
Domain d5jhaa3: 5jha A:726-1088 [331076] Other proteins in same PDB: d5jhaa1, d5jhaa2, d5jhaa4 automated match to d1he8a4 complexed with 6k7, so4 |
Domain d5jhba3: 5jhb A:726-1091 [331073] Other proteins in same PDB: d5jhba1, d5jhba2, d5jhba4 automated match to d1he8a4 complexed with 6k5, so4 |
Domain d5kaea4: 5kae A:726-1092 [335599] Other proteins in same PDB: d5kaea1, d5kaea2, d5kaea3 automated match to d1he8a4 complexed with 6rf, so4 |
Domain d5oq4a4: 5oq4 A:726-1091 [338602] Other proteins in same PDB: d5oq4a1, d5oq4a2, d5oq4a3 automated match to d1e8za4 complexed with a3w, so4 |
Domain d5t23a3: 5t23 A:726-1087 [333240] Other proteins in same PDB: d5t23a1, d5t23a2, d5t23a4 automated match to d1he8a4 complexed with 74f |
Domain d6c1sa4: 6c1s A:726-1090 [353859] Other proteins in same PDB: d6c1sa1, d6c1sa2, d6c1sa3 automated match to d1he8a4 complexed with efv, so4 |
Domain d6fh5a3: 6fh5 A:726-1087 [363308] Other proteins in same PDB: d6fh5a1, d6fh5a2 automated match to d1he8a4 complexed with dd8 |
Domain d6gq7a3: 6gq7 A:726-1087 [353814] Other proteins in same PDB: d6gq7a1, d6gq7a2 automated match to d1he8a4 complexed with dd8 |
Domain d6t3ba3: 6t3b A:726-1087 [378760] Other proteins in same PDB: d6t3ba1, d6t3ba2 automated match to d1he8a4 complexed with m9t |
Domain d6t3ca3: 6t3c A:726-1092 [378783] Other proteins in same PDB: d6t3ca1, d6t3ca2 automated match to d1he8a4 protein/DNA complex; complexed with mbw |
Domain d6xrla3: 6xrl A:726-1091 [393408] Other proteins in same PDB: d6xrla1, d6xrla2 automated match to d1he8a4 complexed with so4, v7y |
Domain d6xrma4: 6xrm A:726-1091 [393393] Other proteins in same PDB: d6xrma1, d6xrma2, d6xrma3 automated match to d1he8a4 complexed with so4, v81 |
Domain d7jwea3: 7jwe A:726-1090 [402119] Other proteins in same PDB: d7jwea1, d7jwea2 automated match to d1he8a4 complexed with vl1 |
Domain d7jwza4: 7jwz A:726-1090 [402065] Other proteins in same PDB: d7jwza1, d7jwza2, d7jwza3 automated match to d1he8a4 complexed with v7y |
Domain d7jx0a3: 7jx0 A:726-1088 [402091] Other proteins in same PDB: d7jx0a1, d7jx0a2 automated match to d1he8a4 complexed with vlv |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.4 Phoshoinositide 3-kinase (PI3K), catalytic domain: