Lineage for Protein: c-src tyrosine kinase

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2586455Protein c-src tyrosine kinase [56155] (3 species)
    PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

Species:

  1. 2586456Chicken (Gallus gallus) [TaxId:9031] [56157] (54 PDB entries)
    1. Domains for 2hwo:
      1. 2586539Domain d2hwoa_: 2hwo A: [204651]
        automated match to d2gqgb_
        complexed with gol, rbs
      2. 2586540Domain d2hwob_: 2hwo B: [204652]
        automated match to d2gqgb_
        complexed with gol, rbs
    2. Domains for 2hwp:
      1. 2586529Domain d2hwpa_: 2hwp A: [204653]
        automated match to d2gqgb_
        complexed with djk
      2. 2586530Domain d2hwpb_: 2hwp B: [204654]
        automated match to d2gqgb_
        complexed with djk
    3. Domains for 2oiq:
      1. 2586466Domain d2oiqa_: 2oiq A: [205275]
        automated match to d2gqgb_
        complexed with gol, sti
      2. 2586467Domain d2oiqb_: 2oiq B: [205276]
        automated match to d2gqgb_
        complexed with gol, sti
    4. Domain for 2ptk:
    5. Domains for 2qi8:
      1. 2586482Domain d2qi8a_: 2qi8 A: [205818]
        automated match to d2gqgb_
        complexed with gol
      2. 2586483Domain d2qi8b_: 2qi8 B: [205819]
        automated match to d2gqgb_
        complexed with gol
    6. Domains for 2qlq:
      1. 2586484Domain d2qlqa_: 2qlq A: [205847]
        automated match to d2gqgb_
        complexed with sr2
      2. 2586485Domain d2qlqb_: 2qlq B: [205848]
        automated match to d2gqgb_
        complexed with sr2
    7. Domains for 2qq7:
      1. 2586488Domain d2qq7a_: 2qq7 A: [205868]
        automated match to d2gqgb_
        complexed with sr2
      2. 2586489Domain d2qq7b_: 2qq7 B: [205869]
        automated match to d2gqgb_
        complexed with sr2
    8. Domain for 3d7t:
    9. Domains for 3dqw:
      1. 2586460Domain d3dqwa_: 3dqw A: [209258]
        automated match to d2gqgb_
        complexed with ags, mg; mutant
      2. 2586461Domain d3dqwb_: 3dqw B: [209259]
        automated match to d2gqgb_
        complexed with ags, mg; mutant
      3. 2586462Domain d3dqwc_: 3dqw C: [209260]
        automated match to d2gqgb_
        complexed with ags, mg; mutant
      4. 2586463Domain d3dqwd_: 3dqw D: [209261]
        automated match to d2gqgb_
        complexed with ags, mg; mutant
    10. Domains for 3dqx:
      1. 2586470Domain d3dqxa_: 3dqx A: [209262]
        automated match to d2gqgb_
        complexed with amp
      2. 2586471Domain d3dqxb_: 3dqx B: [209263]
        automated match to d2gqgb_
        complexed with amp
    11. Domain for 3el7:
    12. Domains for 3el8:
      1. 2586472Domain d3el8a_: 3el8 A: [209551]
        automated match to d2gqgb_
        complexed with pd5
      2. 2586473Domain d3el8b_: 3el8 B: [209552]
        automated match to d2gqgb_
        complexed with pd5
    13. Domains for 3en4:
      1. 2586537Domain d3en4a_: 3en4 A: [209553]
        automated match to d2gqgb_
        complexed with ks1
      2. 2586538Domain d3en4b_: 3en4 B: [209554]
        automated match to d2gqgb_
        complexed with ks1
    14. Domains for 3en5:
      1. 2586549Domain d3en5a_: 3en5 A: [209555]
        automated match to d2gqgb_
        complexed with ks4
      2. 2586550Domain d3en5b_: 3en5 B: [209556]
        automated match to d2gqgb_
        complexed with ks4
    15. Domains for 3en6:
      1. 2586525Domain d3en6a_: 3en6 A: [209557]
        automated match to d2gqgb_
        complexed with ks5
      2. 2586526Domain d3en6b_: 3en6 B: [209558]
        automated match to d2gqgb_
        complexed with ks5
    16. Domains for 3en7:
      1. 2586555Domain d3en7a_: 3en7 A: [209559]
        automated match to d2gqgb_
        complexed with abj
      2. 2586556Domain d3en7b_: 3en7 B: [209560]
        automated match to d2gqgb_
        complexed with abj
    17. Domains for 3f6x:
      1. 2586496Domain d3f6xa_: 3f6x A: [209814]
        automated match to d2gqgb_
        complexed with ihh
      2. 2586497Domain d3f6xb_: 3f6x B: [209815]
        automated match to d2gqgb_
        complexed with ihh
      3. 2586498Domain d3f6xc_: 3f6x C: [209816]
        automated match to d2gqgb_
        complexed with ihh
      4. 2586499Domain d3f6xd_: 3f6x D: [209817]
        automated match to d2gqgb_
        complexed with ihh
    18. Domains for 3g6g:
      1. 2586486Domain d3g6ga_: 3g6g A: [210419]
        automated match to d2gqgb_
        complexed with g6g, gol
      2. 2586487Domain d3g6gb_: 3g6g B: [210420]
        automated match to d2gqgb_
        complexed with g6g, gol
    19. Domains for 3g6h:
      1. 2586492Domain d3g6ha_: 3g6h A: [210421]
        automated match to d2gqgb_
        complexed with g6h
      2. 2586493Domain d3g6hb_: 3g6h B: [210422]
        automated match to d2gqgb_
        complexed with g6h
    20. Domains for 3geq:
      1. 2586476Domain d3geqa1: 3geq A:251-533 [210515]
        Other proteins in same PDB: d3geqa2, d3geqb2
        automated match to d2z8ca1
        complexed with pp2
      2. 2586477Domain d3geqb1: 3geq B:251-533 [210516]
        Other proteins in same PDB: d3geqa2, d3geqb2
        automated match to d2z8ca1
        complexed with pp2
    21. Domains for 3oez:
      1. 2586478Domain d3oeza_: 3oez A: [214324]
        automated match to d2gqgb_
        complexed with act, gol, sti; mutant
      2. 2586479Domain d3oezb_: 3oez B: [214325]
        automated match to d2gqgb_
        complexed with act, gol, sti; mutant
    22. Domains for 3of0:
      1. 2586513Domain d3of0a_: 3of0 A: [214326]
        automated match to d2gqgb_
        mutant
      2. 2586514Domain d3of0b_: 3of0 B: [214327]
        automated match to d2gqgb_
        mutant
    23. Domains for 3qlf:
      1. 2586500Domain d3qlfa_: 3qlf A: [215282]
        automated match to d2gqgb_
        complexed with pd5; mutant
      2. 2586501Domain d3qlfb_: 3qlf B: [215283]
        automated match to d2gqgb_
        complexed with pd5; mutant
    24. Domains for 3qlg:
      1. 2586509Domain d3qlga_: 3qlg A: [215284]
        automated match to d2gqgb_
        complexed with 1n1; mutant
      2. 2586510Domain d3qlgb_: 3qlg B: [215285]
        automated match to d2gqgb_
        complexed with 1n1; mutant
    25. Domains for 3svv:
      1. 2586458Domain d3svva_: 3svv A: [216579]
        automated match to d2gqgb_
        complexed with vsp
      2. 2586459Domain d3svvb_: 3svv B: [216580]
        automated match to d2gqgb_
        complexed with vsp
    26. Domains for 3tz9:
      1. 2586527Domain d3tz9a_: 3tz9 A: [250047]
        automated match to d3geqa_
        complexed with aqu
      2. 2586528Domain d3tz9b_: 3tz9 B: [250048]
        automated match to d3geqa_
        complexed with aqu
    27. Domain for 3u4w:
    28. Domains for 3u51:
      1. 2586464Domain d3u51a_: 3u51 A: [217197]
        automated match to d2etmb_
        protein/DNA complex; complexed with 08x
      2. 2586465Domain d3u51b_: 3u51 B: [217198]
        automated match to d2etmb_
        protein/DNA complex; complexed with 08x
    29. Domains for 3uqf:
      1. 2586474Domain d3uqfa_: 3uqf A: [217487]
        automated match to d2gqgb_
        complexed with bk5
      2. 2586475Domain d3uqfb_: 3uqf B: [217488]
        automated match to d2gqgb_
        complexed with bk5
    30. Domains for 3uqg:
      1. 2586468Domain d3uqga_: 3uqg A: [217489]
        automated match to d2gqgb_
        complexed with b5a
      2. 2586469Domain d3uqgb_: 3uqg B: [217490]
        automated match to d2gqgb_
        complexed with b5a
    31. Domains for 4dgg:
      1. 2586494Domain d4dgga_: 4dgg A: [219751]
        automated match to d2gqgb_
        complexed with i76
      2. 2586495Domain d4dggb_: 4dgg B: [219752]
        automated match to d2gqgb_
        complexed with i76
    32. Domains for 4lgg:
      1. 2586522Domain d4lgga_: 4lgg A: [224662]
        automated match to d1mp8a_
        complexed with vgg
      2. 2586523Domain d4lggb_: 4lgg B: [224663]
        automated match to d1mp8a_
        complexed with vgg
    33. Domains for 4lgh:
      1. 2586557Domain d4lgha_: 4lgh A: [224664]
        automated match to d2z8ca1
        complexed with 0jn
      2. 2586558Domain d4lghb_: 4lgh B: [224665]
        automated match to d2z8ca1
        complexed with 0jn
    34. Domains for 4mcv:
      1. 2586551Domain d4mcva_: 4mcv A: [229911]
        automated match to d4mcvb_
        complexed with 29k
      2. 2586552Domain d4mcvb_: 4mcv B: [229139]
        automated match to d4lgha_
        complexed with 29k
    35. Domains for 4o2p:
      1. 2586504Domain d4o2pa_: 4o2p A: [269721]
        automated match to d3geqa_
        complexed with 11v
      2. 2586505Domain d4o2pb_: 4o2p B: [269725]
        automated match to d3geqa_
        complexed with 11v
    36. Domains for 4u5j:
      1. 2586516Domain d4u5ja_: 4u5j A: [259742]
        automated match to d3geqa_
        complexed with rxt
      2. 2586517Domain d4u5jb_: 4u5j B: [263955]
        automated match to d3geqa_
        complexed with rxt
    37. Domains for 4ybj:
      1. 2586547Domain d4ybja_: 4ybj A: [312023]
        automated match to d3f6xa_
        complexed with 4a9
      2. 2586548Domain d4ybjb_: 4ybj B: [312039]
        automated match to d3f6xa_
        complexed with 4a9
    38. Domain for 4ybk:
    39. Domains for 5d10:
      1. 2586553Domain d5d10a_: 5d10 A: [276564]
        automated match to d3geqa_
        complexed with 563
      2. 2586554Domain d5d10b_: 5d10 B: [276565]
        automated match to d3geqa_
        complexed with 563
    40. Domains for 5d11:
      1. 2586520Domain d5d11a_: 5d11 A: [276713]
        automated match to d3geqa_
        complexed with 56g, gol
      2. 2586521Domain d5d11b_: 5d11 B: [276714]
        automated match to d3geqa_
        complexed with 56g, gol
    41. Domains for 5d12:
      1. 2586563Domain d5d12a_: 5d12 A: [276716]
        automated match to d3geqa_
        complexed with g97
      2. 2586564Domain d5d12b_: 5d12 B: [276715]
        automated match to d3geqa_
        complexed with g97
    42. Domains for 5j5s:
      1. 2586511Domain d5j5sa_: 5j5s A: [318016]
        automated match to d3f6xa_
        complexed with 6g3
      2. 2586512Domain d5j5sb_: 5j5s B: [317992]
        automated match to d3f6xa_
        complexed with 6g3
    43. Domains for 5k9i:
      1. 2586532Domain d5k9ia_: 5k9i A: [329269]
        automated match to d3f6xa_
        complexed with o44
      2. 2586533Domain d5k9ib_: 5k9i B: [329256]
        automated match to d3f6xa_
        complexed with o44
    44. Domains for 5swh:
      1. 2586535Domain d5swha_: 5swh A: [338127]
        automated match to d3f6xa_
        complexed with 71d
      2. 2586536Domain d5swhb_: 5swh B: [337948]
        automated match to d3f6xa_
        complexed with 71d
    45. Domains for 5sys:
      1. 2586559Domain d5sysa_: 5sys A: [337918]
        automated match to d3f6xa_
        complexed with 72f
      2. 2586560Domain d5sysb_: 5sys B: [338055]
        automated match to d3f6xa_
        complexed with 72f
    46. Domains for 5t0p:
      1. 2586541Domain d5t0pa_: 5t0p A: [338251]
        automated match to d3f6xa_
        complexed with 73a
      2. 2586542Domain d5t0pb_: 5t0p B: [338252]
        automated match to d3f6xa_
        complexed with 73a
    47. Domains for 5teh:
      1. 2586561Domain d5teha_: 5teh A: [339611]
        automated match to d3f6xa_
        complexed with s56
      2. 2586562Domain d5tehb_: 5teh B: [339612]
        automated match to d3f6xa_
        complexed with s56
    48. Domains for 5xp5:
      1. 2586507Domain d5xp5a_: 5xp5 A: [348832]
        automated match to d3f6xa_
        complexed with 8bu, mg
      2. 2586508Domain d5xp5b_: 5xp5 B: [349120]
        automated match to d3f6xa_
        complexed with 8bu, mg
    49. Domains for 5xp7:
      1. 2586490Domain d5xp7a_: 5xp7 A: [338860]
        automated match to d3f6xa_
        complexed with 8c6, gol, mg
      2. 2586491Domain d5xp7b_: 5xp7 B: [338839]
        automated match to d3f6xa_
        complexed with 8c6, gol, mg
    50. Domain for 6ate:
    51. Domains for 6hve:
      1. 2586480Domain d6hvea_: 6hve A: [376078]
        automated match to d2hwoa_
        complexed with guw
      2. 2586481Domain d6hveb_: 6hve B: [376047]
        automated match to d2hwoa_
        complexed with guw
    52. Domains for 6hvf:
      1. 2586502Domain d6hvfa_: 6hvf A: [376095]
        automated match to d2hwoa_
        complexed with edo, gut
      2. 2586503Domain d6hvfb_: 6hvf B: [376014]
        automated match to d2hwoa_
        complexed with edo, gut
    53. Domains for 6l8l:
      1. 2586543Domain d6l8la_: 6l8l A: [395190]
        automated match to d3f6xa_
        complexed with 1e8
      2. 2586544Domain d6l8lb_: 6l8l B: [395155]
        automated match to d3f6xa_
        complexed with 1e8
      3. 2586545Domain d6l8lc_: 6l8l C: [395248]
        automated match to d3f6xa_
        complexed with 1e8
      4. 2586546Domain d6l8ld_: 6l8l D: [395178]
        automated match to d3f6xa_
        complexed with 1e8
    54. Domains for 6wiw:
      1. 2586518Domain d6wiwa_: 6wiw A: [388097]
        automated match to d3f6xa_
        complexed with i14
      2. 2586519Domain d6wiwb_: 6wiw B: [388029]
        automated match to d3f6xa_
        complexed with i14
  2. 2586565Human (Homo sapiens) [TaxId:9606] [56156] (13 PDB entries)
    1. Domain for 1fmk:
    2. Domain for 1ksw:
    3. Domain for 1y57:
    4. Domains for 2bdf:
      1. 2586568Domain d2bdfa_: 2bdf A: [128336]
        automated match to d3bz3a_
        complexed with 24a
      2. 2586569Domain d2bdfb_: 2bdf B: [128337]
        automated match to d3bz3a_
        complexed with 24a
    5. Domain for 2bdj:
    6. Domain for 2h8h:
    7. Domain for 2src:
    8. Domain for 4k11:
    9. Domains for 4mxo:
      1. 2586572Domain d4mxoa_: 4mxo A: [229461]
        automated match to d3en6b_
        complexed with db8
      2. 2586573Domain d4mxob_: 4mxo B: [229462]
        automated match to d3en6b_
        complexed with db8
    10. Domains for 4mxx:
      1. 2586588Domain d4mxxa_: 4mxx A: [229457]
        automated match to d3en6b_
        complexed with db8; mutant
      2. 2586589Domain d4mxxb_: 4mxx B: [235704]
        automated match to d4mxxa_
        complexed with db8; mutant
    11. Domains for 4mxy:
      1. 2586584Domain d4mxya_: 4mxy A: [230165]
        automated match to d4mxza_
        complexed with db8; mutant
      2. 2586585Domain d4mxyb_: 4mxy B: [230166]
        automated match to d4mxza_
        complexed with db8; mutant
    12. Domains for 4mxz:
      1. 2586586Domain d4mxza_: 4mxz A: [229459]
        automated match to d3en6b_
        complexed with db8; mutant
      2. 2586587Domain d4mxzb_: 4mxz B: [229460]
        automated match to d3en6b_
        complexed with db8; mutant
    13. Domains for 6e6e:
      1. 2586574Domain d6e6ea_: 6e6e A: [372410]
        automated match to d4mxob_
        complexed with hvy
      2. 2586575Domain d6e6eb_: 6e6e B: [372297]
        automated match to d4mxob_
        complexed with hvy
      3. 2586576Domain d6e6ec_: 6e6e C: [372359]
        automated match to d4mxob_
        complexed with hvy
      4. 2586577Domain d6e6ed_: 6e6e D: [372381]
        automated match to d4mxob_
        complexed with hvy
      5. 2586578Domain d6e6ee_: 6e6e E: [372351]
        automated match to d4mxob_
        complexed with hvy
      6. 2586579Domain d6e6ef_: 6e6e F: [372315]
        automated match to d4mxob_
        complexed with hvy
      7. 2586580Domain d6e6eg_: 6e6e G: [372332]
        automated match to d4mxob_
        complexed with hvy
      8. 2586581Domain d6e6eh_: 6e6e H: [372375]
        automated match to d4mxob_
        complexed with hvy
  3. 2586591Mus musculus [TaxId:10090] [350472] (1 PDB entry)

More info for Protein c-src tyrosine kinase from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein c-src tyrosine kinase from d.144.1.7: Protein kinases, catalytic subunit: