SCOP 1.73: Protein: MAP kinase p38

Lineage for Protein: MAP kinase p38

Root: SCOP 1.73
Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
members organized in the groups and subfamiles specified by the comments
Protein MAP kinase p38 [56129] (2 species)
CMGC group; ERK/MAPK subfamily; serine/threonine kinase

Species:

Human (Homo sapiens) [TaxId:9606] [56130] (41 PDB entries)
1. Domain for 1a9u:
  - Domain d1a9ua_: 1a9u A: [41646]
    complexed with sb2; mutant
2. Domain for 1bl6:
  - Domain d1bl6a_: 1bl6 A: [41647]
    complexed with sb6; mutant
3. Domain for 1bl7:
  - Domain d1bl7a_: 1bl7 A: [41648]
    complexed with sb4; mutant
4. Domain for 1bmk:
  - Domain d1bmka_: 1bmk A: [41644]
    complexed with sb5; mutant
5. Domain for 1di9:
  - Domain d1di9a_: 1di9 A: [41649]
    complexed with msq
6. Domain for 1ian:
  - Domain d1iana_: 1ian A: [41645]
    complexed with d13; mutant
7. Domain for 1kv1:
  - Domain d1kv1a_: 1kv1 A: [73025]
    complexed with bmu
8. Domain for 1kv2:
  - Domain d1kv2a_: 1kv2 A: [73026]
    complexed with b96
9. Domain for 1m7q:
  - Domain d1m7qa_: 1m7q A: [78744]
    complexed with dqo, so4
10. Domain for 1ouk:
  - Domain d1ouka_: 1ouk A: [93548]
    complexed with 084, so4
11. Domain for 1ouy:
  - Domain d1ouya_: 1ouy A: [93579]
    complexed with 094
12. Domain for 1ove:
  - Domain d1ovea_: 1ove A: [93595]
    complexed with 358, gol; mutant
13. Domain for 1oz1:
  - Domain d1oz1a_: 1oz1 A: [93780]
    complexed with fph
14. Domain for 1r39:
  - Domain d1r39a_: 1r39 A: [96905]
    complexed with so4
15. Domain for 1r3c:
  - Domain d1r3ca_: 1r3c A: [96906]
    complexed with mg; mutant
16. Domain for 1w7h:
  - Domain d1w7ha1: 1w7h A:5-352 [120684]
    automatically matched to d1a9u__
    complexed with 3ip
17. Domain for 1w82:
  - Domain d1w82a1: 1w82 A:5-352 [120709]
    automatically matched to d1a9u__
    complexed with l10
18. Domain for 1w83:
  - Domain d1w83a1: 1w83 A:5-352 [120710]
    automatically matched to d1a9u__
    complexed with l11
19. Domain for 1w84:
  - Domain d1w84a1: 1w84 A:5-352 [120711]
    automatically matched to d1a9u__
    complexed with l12
20. Domain for 1wbn:
  - Domain d1wbna1: 1wbn A:5-352 [120850]
    automatically matched to d1a9u__
    complexed with l09
21. Domain for 1wbo:
  - Domain d1wboa1: 1wbo A:5-352 [120851]
    automatically matched to d1a9u__
    complexed with 2ch
22. Domain for 1wbs:
  - Domain d1wbsa1: 1wbs A:5-352 [120860]
    automatically matched to d1a9u__
    complexed with gol, li2
23. Domain for 1wbt:
  - Domain d1wbta1: 1wbt A:5-352 [120861]
    automatically matched to d1a9u__
    complexed with wbt
24. Domain for 1wbv:
  - Domain d1wbva1: 1wbv A:5-352 [120864]
    automatically matched to d1a9u__
    complexed with dms, gol, li3
25. Domain for 1wbw:
  - Domain d1wbwa1: 1wbw A:5-352 [120865]
    automatically matched to d1a9u__
    complexed with li4
26. Domain for 1wfc:
  - Domain d1wfca_: 1wfc A: [41643]
27. Domain for 1yqj:
  - Domain d1yqja1: 1yqj A:5-352 [123888]
    automatically matched to d1a9u__
    complexed with 6np, so4
28. Domain for 1zyj:
  - Domain d1zyja1: 1zyj A:5-352 [125829]
    automatically matched to d1a9u__
    complexed with bi5, bog
29. Domain for 1zz2:
  - Domain d1zz2a1: 1zz2 A:5-352 [125871]
    automatically matched to d1a9u__
    complexed with b11, bog
30. Domain for 1zzl:
  - Domain d1zzla1: 1zzl A:5-352 [125910]
    automatically matched to d1a9u__
    complexed with tzy
31. Domain for 2baj:
  - Domain d2baja1: 2baj A:5-352 [128238]
    automatically matched to d1a9u__
    complexed with 1pp
32. Domain for 2bak:
  - Domain d2baka1: 2bak A:5-352 [128239]
    automatically matched to d1a9u__
    complexed with aqz
33. Domain for 2bal:
  - Domain d2bala1: 2bal A:5-352 [128240]
    automatically matched to d1a9u__
    complexed with pqa
34. Domain for 2ewa:
  - Domain d2ewaa1: 2ewa A:5-354 [132451]
    automatically matched to d1a9u__
    complexed with sb2
35. Domain for 2gfs:
  - Domain d2gfsa1: 2gfs A:5-352 [135109]
    automatically matched to d1a9u__
    complexed with pqb
36. Domain for 2gtm:
  - Domain d2gtma1: 2gtm A:5-352 [135676]
    automatically matched to d1bmka_
    complexed with lid
37. Domain for 2gtn:
  - Domain d2gtna1: 2gtn A:5-352 [135677]
    automatically matched to d1bmka_
    complexed with lie, so4
38. Domain for 2i0h:
  - Domain d2i0ha1: 2i0h A:4-352 [136952]
    automatically matched to d1ovea_
    complexed with 222, gol; mutant
39. Domains for 2okr:
  1. Domain d2okra1: 2okr A:4-352 [139128]
    automatically matched to d1a9u__
  2. Domain d2okrd1: 2okr D:5-352 [139129]
    automatically matched to d1a9u__
40. Domains for 2onl:
  1. Domain d2onla1: 2onl A:4-352 [139158]
    Other proteins in same PDB: d2onlc1, d2onld1
    automatically matched to d1a9u__
  2. Domain d2onlb1: 2onl B:4-352 [139159]
    Other proteins in same PDB: d2onlc1, d2onld1
    automatically matched to d1a9u__
41. Domain for 2oza:
  - Domain d2ozab1: 2oza B:6-352 [139444]
    Other proteins in same PDB: d2ozaa1
    automatically matched to d1bmka_
Mouse (Mus musculus) [TaxId:10090] [56131] (3 PDB entries)
1. Domain for 1lew:
  - Domain d1lewa_: 1lew A: [73875]
2. Domain for 1lez:
  - Domain d1leza_: 1lez A: [73876]
    mutant
3. Domain for 1p38:
  - Domain d1p38a_: 1p38 A: [41650]
    mutant

More info for Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit:

Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit first appeared (with stable ids) in SCOP 1.55, called Protein MAP kinase p38 from d.144.1.1: Serine/threonin kinases
Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOP 1.71
Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOP 1.75
Protein MAP kinase p38 from d.144.1.7: Protein kinases, catalytic subunit appears in the current release, SCOPe 2.08