SCOPe 2.08: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.135: The spindle assembly checkpoint protein mad2 [56018] (1 superfamily)
core: alpha(2)-beta(2)-alpha-beta; mixed sheet: order 213

N- and C-termini undergo large conformational rearrangement upon ligand binding
automatically mapped to Pfam PF02301

Family d.135.1.1: The spindle assembly checkpoint protein mad2 [56020] (2 proteins)
Protein The spindle assembly checkpoint protein mad2 [56021] (1 species)
Species Human (Homo sapiens) [TaxId:9606] [56022] (5 PDB entries)

Domain(s) for 1duj:
- Domain d1duja1: 1duj A:13-197 [41449]
  Other proteins in same PDB: d1duja2
  "apo" form
Domain(s) for 1go4:
1. Domain d1go4a_: 1go4 A: [70292]
  Other proteins in same PDB: d1go4e_, d1go4f_, d1go4g_, d1go4h_
  complex with mad1
2. Domain d1go4b_: 1go4 B: [70293]
  Other proteins in same PDB: d1go4e_, d1go4f_, d1go4g_, d1go4h_
  complex with mad1
3. Domain d1go4c_: 1go4 C: [70294]
  Other proteins in same PDB: d1go4e_, d1go4f_, d1go4g_, d1go4h_
  complex with mad1
4. Domain d1go4d_: 1go4 D: [70295]
  Other proteins in same PDB: d1go4e_, d1go4f_, d1go4g_, d1go4h_
  complex with mad1
Domain(s) for 1klq:
- Domain d1klqa1: 1klq A:13-207 [68689]
  Other proteins in same PDB: d1klqa2
  complex with MBP1 peptide
Domain(s) for 1s2h:
- Domain d1s2ha_: 1s2h A: [98385]
Domain(s) for 2qyf:
1. Domain d2qyfa_: 2qyf A: [167878]
  automated match to d1s2ha_
2. Domain d2qyfc_: 2qyf C: [167879]
  automated match to d1s2ha_

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.135.1.1 The spindle assembly checkpoint protein mad2:

Species Human (Homo sapiens) [TaxId:9606] from d.135.1.1 The spindle assembly checkpoint protein mad2 first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from d.135.1.1 The spindle assembly checkpoint protein mad2 appears in SCOPe 2.07