Lineage for Protein: S-adenosylmethionine synthetase

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2582825Fold d.130: S-adenosylmethionine synthetase [55972] (1 superfamily)
    duplication: consists of 3 similar intertwined domains
    structural repeat: beta-alpha-beta(2)-alpha-beta; two layers, alpha/beta
  4. 2582826Superfamily d.130.1: S-adenosylmethionine synthetase [55973] (2 families) (S)
  5. 2582827Family d.130.1.1: S-adenosylmethionine synthetase [55974] (2 proteins)
  6. 2582828Protein S-adenosylmethionine synthetase [55975] (3 species)
    synonym: methionine adenosyltransferase, MAT

Species:

  1. 2582829Escherichia coli [TaxId:562] [55976] (9 PDB entries)
    1. Domains for 1fug:
      1. 2582872Domain d1fuga1: 1fug A:1-102 [41344]
      2. 2582873Domain d1fuga2: 1fug A:103-231 [41345]
      3. 2582874Domain d1fuga3: 1fug A:232-383 [41346]
      4. 2582875Domain d1fugb1: 1fug B:1-102 [41347]
      5. 2582876Domain d1fugb2: 1fug B:103-231 [41348]
      6. 2582877Domain d1fugb3: 1fug B:232-383 [41349]
    2. Domains for 1mxa:
      1. 2582830Domain d1mxaa1: 1mxa A:1-102 [41326]
        complexed with k, mg, po4, pop
      2. 2582831Domain d1mxaa2: 1mxa A:108-231 [41327]
        complexed with k, mg, po4, pop
      3. 2582832Domain d1mxaa3: 1mxa A:232-383 [41328]
        complexed with k, mg, po4, pop
    3. Domains for 1mxb:
      1. 2582833Domain d1mxba1: 1mxb A:1-102 [41329]
        complexed with adp, k, mg, po4
      2. 2582834Domain d1mxba2: 1mxb A:108-231 [41330]
        complexed with adp, k, mg, po4
      3. 2582835Domain d1mxba3: 1mxb A:232-383 [41331]
        complexed with adp, k, mg, po4
    4. Domains for 1mxc:
      1. 2582836Domain d1mxca1: 1mxc A:1-102 [41332]
        complexed with abp, k, mg, po4
      2. 2582837Domain d1mxca2: 1mxc A:108-231 [41333]
        complexed with abp, k, mg, po4
      3. 2582838Domain d1mxca3: 1mxc A:232-383 [41334]
        complexed with abp, k, mg, po4
    5. Domains for 1p7l:
      1. 2582860Domain d1p7la1: 1p7l A:1-102 [94295]
        complexed with anp, k, met, mg, ppk, sam
      2. 2582861Domain d1p7la2: 1p7l A:103-231 [94296]
        complexed with anp, k, met, mg, ppk, sam
      3. 2582862Domain d1p7la3: 1p7l A:232-383 [94297]
        complexed with anp, k, met, mg, ppk, sam
      4. 2582863Domain d1p7lb1: 1p7l B:1-102 [94298]
        complexed with anp, k, met, mg, ppk, sam
      5. 2582864Domain d1p7lb2: 1p7l B:103-231 [94299]
        complexed with anp, k, met, mg, ppk, sam
      6. 2582865Domain d1p7lb3: 1p7l B:232-383 [94300]
        complexed with anp, k, met, mg, ppk, sam
      7. 2582866Domain d1p7lc1: 1p7l C:1-102 [94301]
        complexed with anp, k, met, mg, ppk, sam
      8. 2582867Domain d1p7lc2: 1p7l C:103-231 [94302]
        complexed with anp, k, met, mg, ppk, sam
      9. 2582868Domain d1p7lc3: 1p7l C:232-383 [94303]
        complexed with anp, k, met, mg, ppk, sam
      10. 2582869Domain d1p7ld1: 1p7l D:1-102 [94304]
        complexed with anp, k, met, mg, ppk, sam
      11. 2582870Domain d1p7ld2: 1p7l D:103-231 [94305]
        complexed with anp, k, met, mg, ppk, sam
      12. 2582871Domain d1p7ld3: 1p7l D:232-383 [94306]
        complexed with anp, k, met, mg, ppk, sam
    6. Domains for 1rg9:
      1. 2582848Domain d1rg9a1: 1rg9 A:1-102 [97427]
        complexed with k, mg, ppk, sam
      2. 2582849Domain d1rg9a2: 1rg9 A:103-231 [97428]
        complexed with k, mg, ppk, sam
      3. 2582850Domain d1rg9a3: 1rg9 A:232-383 [97429]
        complexed with k, mg, ppk, sam
      4. 2582851Domain d1rg9b1: 1rg9 B:1-102 [97430]
        complexed with k, mg, ppk, sam
      5. 2582852Domain d1rg9b2: 1rg9 B:103-231 [97431]
        complexed with k, mg, ppk, sam
      6. 2582853Domain d1rg9b3: 1rg9 B:232-383 [97432]
        complexed with k, mg, ppk, sam
      7. 2582854Domain d1rg9c1: 1rg9 C:1-102 [97433]
        complexed with k, mg, ppk, sam
      8. 2582855Domain d1rg9c2: 1rg9 C:103-231 [97434]
        complexed with k, mg, ppk, sam
      9. 2582856Domain d1rg9c3: 1rg9 C:232-383 [97435]
        complexed with k, mg, ppk, sam
      10. 2582857Domain d1rg9d1: 1rg9 D:1-102 [97436]
        complexed with k, mg, ppk, sam
      11. 2582858Domain d1rg9d2: 1rg9 D:103-231 [97437]
        complexed with k, mg, ppk, sam
      12. 2582859Domain d1rg9d3: 1rg9 D:232-383 [97438]
        complexed with k, mg, ppk, sam
    7. Domains for 1xra:
      1. 2582845Domain d1xraa1: 1xra A:1-101 [41341]
        complexed with k, mg, po4
      2. 2582846Domain d1xraa2: 1xra A:108-231 [41342]
        complexed with k, mg, po4
      3. 2582847Domain d1xraa3: 1xra A:232-383 [41343]
        complexed with k, mg, po4
    8. Domains for 1xrb:
      1. 2582839Domain d1xrba1: 1xrb A:1-101 [41335]
        complexed with k, mg, po4
      2. 2582840Domain d1xrba2: 1xrb A:108-231 [41336]
        complexed with k, mg, po4
      3. 2582841Domain d1xrba3: 1xrb A:232-383 [41337]
        complexed with k, mg, po4
    9. Domains for 1xrc:
      1. 2582842Domain d1xrca1: 1xrc A:1-101 [41338]
        complexed with co, k, po4
      2. 2582843Domain d1xrca2: 1xrc A:108-231 [41339]
        complexed with co, k, po4
      3. 2582844Domain d1xrca3: 1xrc A:232-383 [41340]
        complexed with co, k, po4
  2. 2582878Human (Homo sapiens), isoform type-2 [TaxId:9606] [160759] (8 PDB entries)
    Uniprot P31153 126-251! Uniprot P31153 16-125! Uniprot P31153 252-395
    MAT2A
    1. Domains for 2hj2:
      1. 2582879Domain d2hj2a1: 2hj2 A:16-125 [304011]
        automated match to d2p02a1
        complexed with cl, sam
      2. 2582880Domain d2hj2a2: 2hj2 A:126-251 [304012]
        automated match to d2p02a2
        complexed with cl, sam
      3. 2582881Domain d2hj2a3: 2hj2 A:252-395 [304013]
        automated match to d2p02a3
        complexed with cl, sam
      4. 2582882Domain d2hj2b1: 2hj2 B:16-125 [304014]
        automated match to d2p02a1
        complexed with cl, sam
      5. 2582883Domain d2hj2b2: 2hj2 B:126-251 [304015]
        automated match to d2p02a2
        complexed with cl, sam
      6. 2582884Domain d2hj2b3: 2hj2 B:252-395 [304016]
        automated match to d2p02a3
        complexed with cl, sam
    2. Domains for 2p02:
      1. 2582900Domain d2p02a1: 2p02 A:38-147 [149132]
        complexed with cl, sam
      2. 2582901Domain d2p02a2: 2p02 A:148-273 [149133]
        complexed with cl, sam
      3. 2582902Domain d2p02a3: 2p02 A:274-417 [149134]
        complexed with cl, sam
    3. Domains for 4ktt:
      1. 2582903Domain d4ktta1: 4ktt A:15-115 [257811]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      2. 2582904Domain d4ktta2: 4ktt A:135-251 [257812]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      3. 2582905Domain d4ktta3: 4ktt A:252-395 [257813]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      4. 2582906Domain d4kttb1: 4ktt B:14-125 [257808]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      5. 2582907Domain d4kttb2: 4ktt B:126-251 [257809]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      6. 2582908Domain d4kttb3: 4ktt B:252-395 [257810]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      7. 2582909Domain d4kttc1: 4ktt C:15-115 [257805]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      8. 2582910Domain d4kttc2: 4ktt C:134-251 [257806]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      9. 2582911Domain d4kttc3: 4ktt C:252-395 [257807]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      10. 2582912Domain d4kttd1: 4ktt D:16-125 [257814]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      11. 2582913Domain d4kttd2: 4ktt D:126-251 [257815]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      12. 2582914Domain d4kttd3: 4ktt D:252-395 [257816]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
    4. Domains for 7kcc:
      1. 2582897Domain d7kcca1: 7kcc A:14-125 [403400]
        automated match to d2p02a1
        complexed with cl, edo, sam, wbg
      2. 2582898Domain d7kcca2: 7kcc A:126-251 [403401]
        automated match to d2p02a2
        complexed with cl, edo, sam, wbg
      3. 2582899Domain d7kcca3: 7kcc A:252-395 [403402]
        automated match to d2p02a3
        complexed with cl, edo, sam, wbg
    5. Domains for 7kce:
      1. 2582888Domain d7kcea1: 7kce A:16-125 [403363]
        automated match to d2p02a1
        complexed with cl, j41, sam
      2. 2582889Domain d7kcea2: 7kce A:126-251 [403364]
        automated match to d2p02a2
        complexed with cl, j41, sam
      3. 2582890Domain d7kcea3: 7kce A:252-395 [403365]
        automated match to d2p02a3
        complexed with cl, j41, sam
    6. Domains for 7kcf:
      1. 2582885Domain d7kcfa1: 7kcf A:14-125 [403341]
        automated match to d2p02a1
        complexed with edo, gol, j4a, sam
      2. 2582886Domain d7kcfa2: 7kcf A:126-251 [403342]
        automated match to d2p02a2
        complexed with edo, gol, j4a, sam
      3. 2582887Domain d7kcfa3: 7kcf A:252-395 [403343]
        automated match to d2p02a3
        complexed with edo, gol, j4a, sam
    7. Domains for 7kda:
      1. 2582894Domain d7kdaa1: 7kda A:15-125 [403380]
        automated match to d2p02a1
        complexed with cl, gol, sam, trs, wbm
      2. 2582895Domain d7kdaa2: 7kda A:126-251 [403381]
        automated match to d2p02a2
        complexed with cl, gol, sam, trs, wbm
      3. 2582896Domain d7kdaa3: 7kda A:252-395 [403382]
        automated match to d2p02a3
        complexed with cl, gol, sam, trs, wbm
    8. Domains for 7kdb:
      1. 2582891Domain d7kdba1: 7kdb A:15-125 [403406]
        automated match to d2p02a1
        complexed with cl, edo, gol, sam, trs, wbs
      2. 2582892Domain d7kdba2: 7kdb A:126-251 [403407]
        automated match to d2p02a2
        complexed with cl, edo, gol, sam, trs, wbs
      3. 2582893Domain d7kdba3: 7kdb A:252-395 [403408]
        automated match to d2p02a3
        complexed with cl, edo, gol, sam, trs, wbs
  3. 2582915Norway rat (Rattus norvegicus) [TaxId:10116] [55977] (5 PDB entries)
    1. Domains for 1o90:
      1. 2582922Domain d1o90a1: 1o90 A:17-116 [92650]
        complexed with k, lis, mg, po4
      2. 2582923Domain d1o90a2: 1o90 A:129-252 [92651]
        complexed with k, lis, mg, po4
      3. 2582924Domain d1o90a3: 1o90 A:253-396 [92652]
        complexed with k, lis, mg, po4
      4. 2582925Domain d1o90b1: 1o90 B:17-116 [92653]
        complexed with k, lis, mg, po4
      5. 2582926Domain d1o90b2: 1o90 B:129-252 [92654]
        complexed with k, lis, mg, po4
      6. 2582927Domain d1o90b3: 1o90 B:253-396 [92655]
        complexed with k, lis, mg, po4
    2. Domains for 1o92:
      1. 2582928Domain d1o92a1: 1o92 A:17-116 [92659]
        complexed with adp, amb, k, mg, po4
      2. 2582929Domain d1o92a2: 1o92 A:129-252 [92660]
        complexed with adp, amb, k, mg, po4
      3. 2582930Domain d1o92a3: 1o92 A:253-396 [92661]
        complexed with adp, amb, k, mg, po4
      4. 2582931Domain d1o92b1: 1o92 B:17-116 [92662]
        complexed with adp, amb, k, mg, po4
      5. 2582932Domain d1o92b2: 1o92 B:129-252 [92663]
        complexed with adp, amb, k, mg, po4
      6. 2582933Domain d1o92b3: 1o92 B:253-396 [92664]
        complexed with adp, amb, k, mg, po4
    3. Domains for 1o93:
      1. 2582934Domain d1o93a1: 1o93 A:17-116 [92665]
        complexed with atp, k, lis, mg, po4
      2. 2582935Domain d1o93a2: 1o93 A:129-252 [92666]
        complexed with atp, k, lis, mg, po4
      3. 2582936Domain d1o93a3: 1o93 A:253-396 [92667]
        complexed with atp, k, lis, mg, po4
      4. 2582937Domain d1o93b1: 1o93 B:17-116 [92668]
        complexed with atp, k, lis, mg, po4
      5. 2582938Domain d1o93b2: 1o93 B:129-252 [92669]
        complexed with atp, k, lis, mg, po4
      6. 2582939Domain d1o93b3: 1o93 B:253-396 [92670]
        complexed with atp, k, lis, mg, po4
    4. Domains for 1o9t:
      1. 2582916Domain d1o9ta1: 1o9t A:17-116 [92685]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      2. 2582917Domain d1o9ta2: 1o9t A:129-252 [92686]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      3. 2582918Domain d1o9ta3: 1o9t A:253-396 [92687]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      4. 2582919Domain d1o9tb1: 1o9t B:17-116 [92688]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      5. 2582920Domain d1o9tb2: 1o9t B:129-252 [92689]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      6. 2582921Domain d1o9tb3: 1o9t B:253-396 [92690]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
    5. Domains for 1qm4:
      1. 2582940Domain d1qm4a1: 1qm4 A:17-116 [41350]
        complexed with amb, k, mg, so4
      2. 2582941Domain d1qm4a2: 1qm4 A:129-252 [41351]
        complexed with amb, k, mg, so4
      3. 2582942Domain d1qm4a3: 1qm4 A:253-396 [41352]
        complexed with amb, k, mg, so4
      4. 2582943Domain d1qm4b1: 1qm4 B:17-116 [41353]
        complexed with amb, k, mg, so4
      5. 2582944Domain d1qm4b2: 1qm4 B:129-252 [41354]
        complexed with amb, k, mg, so4
      6. 2582945Domain d1qm4b3: 1qm4 B:253-396 [41355]
        complexed with amb, k, mg, so4

More info for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase

Timeline for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase: