Lineage for Protein: S-adenosylmethionine synthetase

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1926950Fold d.130: S-adenosylmethionine synthetase [55972] (1 superfamily)
    duplication: consists of 3 similar intertwined domains
    structural repeat: beta-alpha-beta(2)-alpha-beta; two layers, alpha/beta
  4. 1926951Superfamily d.130.1: S-adenosylmethionine synthetase [55973] (2 families) (S)
  5. 1926952Family d.130.1.1: S-adenosylmethionine synthetase [55974] (1 protein)
  6. 1926953Protein S-adenosylmethionine synthetase [55975] (3 species)
    synonym: methionine adenosyltransferase, MAT

Species:

  1. 1926954Escherichia coli [TaxId:562] [55976] (9 PDB entries)
    1. Domains for 1fug:
      1. 1926997Domain d1fuga1: 1fug A:1-102 [41344]
      2. 1926998Domain d1fuga2: 1fug A:103-231 [41345]
      3. 1926999Domain d1fuga3: 1fug A:232-383 [41346]
      4. 1927000Domain d1fugb1: 1fug B:1-102 [41347]
      5. 1927001Domain d1fugb2: 1fug B:103-231 [41348]
      6. 1927002Domain d1fugb3: 1fug B:232-383 [41349]
    2. Domains for 1mxa:
      1. 1926955Domain d1mxaa1: 1mxa A:1-102 [41326]
        complexed with k, mg, po4, pop
      2. 1926956Domain d1mxaa2: 1mxa A:108-231 [41327]
        complexed with k, mg, po4, pop
      3. 1926957Domain d1mxaa3: 1mxa A:232-383 [41328]
        complexed with k, mg, po4, pop
    3. Domains for 1mxb:
      1. 1926958Domain d1mxba1: 1mxb A:1-102 [41329]
        complexed with adp, k, mg, po4
      2. 1926959Domain d1mxba2: 1mxb A:108-231 [41330]
        complexed with adp, k, mg, po4
      3. 1926960Domain d1mxba3: 1mxb A:232-383 [41331]
        complexed with adp, k, mg, po4
    4. Domains for 1mxc:
      1. 1926961Domain d1mxca1: 1mxc A:1-102 [41332]
        complexed with abp, k, mg, po4
      2. 1926962Domain d1mxca2: 1mxc A:108-231 [41333]
        complexed with abp, k, mg, po4
      3. 1926963Domain d1mxca3: 1mxc A:232-383 [41334]
        complexed with abp, k, mg, po4
    5. Domains for 1p7l:
      1. 1926982Domain d1p7la1: 1p7l A:1-102 [94295]
        complexed with anp, k, met, mg, ppk, sam
      2. 1926983Domain d1p7la2: 1p7l A:103-231 [94296]
        complexed with anp, k, met, mg, ppk, sam
      3. 1926984Domain d1p7la3: 1p7l A:232-383 [94297]
        complexed with anp, k, met, mg, ppk, sam
      4. 1926985Domain d1p7lb1: 1p7l B:1-102 [94298]
        complexed with anp, k, met, mg, ppk, sam
      5. 1926986Domain d1p7lb2: 1p7l B:103-231 [94299]
        complexed with anp, k, met, mg, ppk, sam
      6. 1926987Domain d1p7lb3: 1p7l B:232-383 [94300]
        complexed with anp, k, met, mg, ppk, sam
      7. 1926988Domain d1p7lc1: 1p7l C:1-102 [94301]
        complexed with anp, k, met, mg, ppk, sam
      8. 1926989Domain d1p7lc2: 1p7l C:103-231 [94302]
        complexed with anp, k, met, mg, ppk, sam
      9. 1926990Domain d1p7lc3: 1p7l C:232-383 [94303]
        complexed with anp, k, met, mg, ppk, sam
      10. 1926991Domain d1p7ld1: 1p7l D:1-102 [94304]
        complexed with anp, k, met, mg, ppk, sam
      11. 1926992Domain d1p7ld2: 1p7l D:103-231 [94305]
        complexed with anp, k, met, mg, ppk, sam
      12. 1926993Domain d1p7ld3: 1p7l D:232-383 [94306]
        complexed with anp, k, met, mg, ppk, sam
    6. Domains for 1rg9:
      1. 1926967Domain d1rg9a1: 1rg9 A:1-102 [97427]
        complexed with k, mg, ppk, sam
      2. 1926968Domain d1rg9a2: 1rg9 A:103-231 [97428]
        complexed with k, mg, ppk, sam
      3. 1926969Domain d1rg9a3: 1rg9 A:232-383 [97429]
        complexed with k, mg, ppk, sam
      4. 1926970Domain d1rg9b1: 1rg9 B:1-102 [97430]
        complexed with k, mg, ppk, sam
      5. 1926971Domain d1rg9b2: 1rg9 B:103-231 [97431]
        complexed with k, mg, ppk, sam
      6. 1926972Domain d1rg9b3: 1rg9 B:232-383 [97432]
        complexed with k, mg, ppk, sam
      7. 1926973Domain d1rg9c1: 1rg9 C:1-102 [97433]
        complexed with k, mg, ppk, sam
      8. 1926974Domain d1rg9c2: 1rg9 C:103-231 [97434]
        complexed with k, mg, ppk, sam
      9. 1926975Domain d1rg9c3: 1rg9 C:232-383 [97435]
        complexed with k, mg, ppk, sam
      10. 1926976Domain d1rg9d1: 1rg9 D:1-102 [97436]
        complexed with k, mg, ppk, sam
      11. 1926977Domain d1rg9d2: 1rg9 D:103-231 [97437]
        complexed with k, mg, ppk, sam
      12. 1926978Domain d1rg9d3: 1rg9 D:232-383 [97438]
        complexed with k, mg, ppk, sam
    7. Domains for 1xra:
      1. 1926994Domain d1xraa1: 1xra A:1-101 [41341]
        complexed with k, mg, po4
      2. 1926995Domain d1xraa2: 1xra A:108-231 [41342]
        complexed with k, mg, po4
      3. 1926996Domain d1xraa3: 1xra A:232-383 [41343]
        complexed with k, mg, po4
    8. Domains for 1xrb:
      1. 1926964Domain d1xrba1: 1xrb A:1-101 [41335]
        complexed with k, mg, po4
      2. 1926965Domain d1xrba2: 1xrb A:108-231 [41336]
        complexed with k, mg, po4
      3. 1926966Domain d1xrba3: 1xrb A:232-383 [41337]
        complexed with k, mg, po4
    9. Domains for 1xrc:
      1. 1926979Domain d1xrca1: 1xrc A:1-101 [41338]
        complexed with co, k, po4
      2. 1926980Domain d1xrca2: 1xrc A:108-231 [41339]
        complexed with co, k, po4
      3. 1926981Domain d1xrca3: 1xrc A:232-383 [41340]
        complexed with co, k, po4
  2. 1927003Human (Homo sapiens), isoform type-2 [TaxId:9606] [160759] (2 PDB entries)
    Uniprot P31153 126-251! Uniprot P31153 16-125! Uniprot P31153 252-395
    MAT2A
    1. Domains for 2p02:
      1. 1927004Domain d2p02a1: 2p02 A:38-147 [149132]
        complexed with cl, sam
      2. 1927005Domain d2p02a2: 2p02 A:148-273 [149133]
        complexed with cl, sam
      3. 1927006Domain d2p02a3: 2p02 A:274-417 [149134]
        complexed with cl, sam
    2. Domains for 4ktt:
      1. 1927007Domain d4ktta1: 4ktt A:15-115 [257811]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      2. 1927008Domain d4ktta2: 4ktt A:135-251 [257812]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      3. 1927009Domain d4ktta3: 4ktt A:252-395 [257813]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      4. 1927010Domain d4kttb1: 4ktt B:14-125 [257808]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      5. 1927011Domain d4kttb2: 4ktt B:126-251 [257809]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      6. 1927012Domain d4kttb3: 4ktt B:252-395 [257810]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      7. 1927013Domain d4kttc1: 4ktt C:15-115 [257805]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      8. 1927014Domain d4kttc2: 4ktt C:134-251 [257806]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      9. 1927015Domain d4kttc3: 4ktt C:252-395 [257807]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      10. 1927016Domain d4kttd1: 4ktt D:16-125 [257814]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      11. 1927017Domain d4kttd2: 4ktt D:126-251 [257815]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      12. 1927018Domain d4kttd3: 4ktt D:252-395 [257816]
        Other proteins in same PDB: d4ktte_, d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
  3. 1927019Norway rat (Rattus norvegicus) [TaxId:10116] [55977] (5 PDB entries)
    1. Domains for 1o90:
      1. 1927032Domain d1o90a1: 1o90 A:17-116 [92650]
        complexed with k, lis, mg, po4
      2. 1927033Domain d1o90a2: 1o90 A:129-252 [92651]
        complexed with k, lis, mg, po4
      3. 1927034Domain d1o90a3: 1o90 A:253-396 [92652]
        complexed with k, lis, mg, po4
      4. 1927035Domain d1o90b1: 1o90 B:17-116 [92653]
        complexed with k, lis, mg, po4
      5. 1927036Domain d1o90b2: 1o90 B:129-252 [92654]
        complexed with k, lis, mg, po4
      6. 1927037Domain d1o90b3: 1o90 B:253-396 [92655]
        complexed with k, lis, mg, po4
    2. Domains for 1o92:
      1. 1927038Domain d1o92a1: 1o92 A:17-116 [92659]
        complexed with adp, amb, k, mg, po4
      2. 1927039Domain d1o92a2: 1o92 A:129-252 [92660]
        complexed with adp, amb, k, mg, po4
      3. 1927040Domain d1o92a3: 1o92 A:253-396 [92661]
        complexed with adp, amb, k, mg, po4
      4. 1927041Domain d1o92b1: 1o92 B:17-116 [92662]
        complexed with adp, amb, k, mg, po4
      5. 1927042Domain d1o92b2: 1o92 B:129-252 [92663]
        complexed with adp, amb, k, mg, po4
      6. 1927043Domain d1o92b3: 1o92 B:253-396 [92664]
        complexed with adp, amb, k, mg, po4
    3. Domains for 1o93:
      1. 1927044Domain d1o93a1: 1o93 A:17-116 [92665]
        complexed with atp, k, lis, mg, po4
      2. 1927045Domain d1o93a2: 1o93 A:129-252 [92666]
        complexed with atp, k, lis, mg, po4
      3. 1927046Domain d1o93a3: 1o93 A:253-396 [92667]
        complexed with atp, k, lis, mg, po4
      4. 1927047Domain d1o93b1: 1o93 B:17-116 [92668]
        complexed with atp, k, lis, mg, po4
      5. 1927048Domain d1o93b2: 1o93 B:129-252 [92669]
        complexed with atp, k, lis, mg, po4
      6. 1927049Domain d1o93b3: 1o93 B:253-396 [92670]
        complexed with atp, k, lis, mg, po4
    4. Domains for 1o9t:
      1. 1927026Domain d1o9ta1: 1o9t A:17-116 [92685]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      2. 1927027Domain d1o9ta2: 1o9t A:129-252 [92686]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      3. 1927028Domain d1o9ta3: 1o9t A:253-396 [92687]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      4. 1927029Domain d1o9tb1: 1o9t B:17-116 [92688]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      5. 1927030Domain d1o9tb2: 1o9t B:129-252 [92689]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      6. 1927031Domain d1o9tb3: 1o9t B:253-396 [92690]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
    5. Domains for 1qm4:
      1. 1927020Domain d1qm4a1: 1qm4 A:17-116 [41350]
        complexed with amb, k, mg, so4
      2. 1927021Domain d1qm4a2: 1qm4 A:129-252 [41351]
        complexed with amb, k, mg, so4
      3. 1927022Domain d1qm4a3: 1qm4 A:253-396 [41352]
        complexed with amb, k, mg, so4
      4. 1927023Domain d1qm4b1: 1qm4 B:17-116 [41353]
        complexed with amb, k, mg, so4
      5. 1927024Domain d1qm4b2: 1qm4 B:129-252 [41354]
        complexed with amb, k, mg, so4
      6. 1927025Domain d1qm4b3: 1qm4 B:253-396 [41355]
        complexed with amb, k, mg, so4

More info for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase

Timeline for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase: