Lineage for Protein: S-adenosylmethionine synthetase

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1669649Fold d.130: S-adenosylmethionine synthetase [55972] (1 superfamily)
    duplication: consists of 3 similar intertwined domains
    structural repeat: beta-alpha-beta(2)-alpha-beta; two layers, alpha/beta
  4. 1669650Superfamily d.130.1: S-adenosylmethionine synthetase [55973] (2 families) (S)
  5. 1669651Family d.130.1.1: S-adenosylmethionine synthetase [55974] (1 protein)
  6. 1669652Protein S-adenosylmethionine synthetase [55975] (3 species)
    synonym: methionine adenosyltransferase, MAT

Species:

  1. 1669653Escherichia coli [TaxId:562] [55976] (9 PDB entries)
    1. Domains for 1fug:
      1. 1669696Domain d1fuga1: 1fug A:1-102 [41344]
      2. 1669697Domain d1fuga2: 1fug A:103-231 [41345]
      3. 1669698Domain d1fuga3: 1fug A:232-383 [41346]
      4. 1669699Domain d1fugb1: 1fug B:1-102 [41347]
      5. 1669700Domain d1fugb2: 1fug B:103-231 [41348]
      6. 1669701Domain d1fugb3: 1fug B:232-383 [41349]
    2. Domains for 1mxa:
      1. 1669654Domain d1mxaa1: 1mxa A:1-102 [41326]
        complexed with k, mg, po4, pop
      2. 1669655Domain d1mxaa2: 1mxa A:108-231 [41327]
        complexed with k, mg, po4, pop
      3. 1669656Domain d1mxaa3: 1mxa A:232-383 [41328]
        complexed with k, mg, po4, pop
    3. Domains for 1mxb:
      1. 1669657Domain d1mxba1: 1mxb A:1-102 [41329]
        complexed with adp, k, mg, po4
      2. 1669658Domain d1mxba2: 1mxb A:108-231 [41330]
        complexed with adp, k, mg, po4
      3. 1669659Domain d1mxba3: 1mxb A:232-383 [41331]
        complexed with adp, k, mg, po4
    4. Domains for 1mxc:
      1. 1669660Domain d1mxca1: 1mxc A:1-102 [41332]
        complexed with abp, k, mg, po4
      2. 1669661Domain d1mxca2: 1mxc A:108-231 [41333]
        complexed with abp, k, mg, po4
      3. 1669662Domain d1mxca3: 1mxc A:232-383 [41334]
        complexed with abp, k, mg, po4
    5. Domains for 1p7l:
      1. 1669681Domain d1p7la1: 1p7l A:1-102 [94295]
        complexed with anp, k, met, mg, ppk, sam
      2. 1669682Domain d1p7la2: 1p7l A:103-231 [94296]
        complexed with anp, k, met, mg, ppk, sam
      3. 1669683Domain d1p7la3: 1p7l A:232-383 [94297]
        complexed with anp, k, met, mg, ppk, sam
      4. 1669684Domain d1p7lb1: 1p7l B:1-102 [94298]
        complexed with anp, k, met, mg, ppk, sam
      5. 1669685Domain d1p7lb2: 1p7l B:103-231 [94299]
        complexed with anp, k, met, mg, ppk, sam
      6. 1669686Domain d1p7lb3: 1p7l B:232-383 [94300]
        complexed with anp, k, met, mg, ppk, sam
      7. 1669687Domain d1p7lc1: 1p7l C:1-102 [94301]
        complexed with anp, k, met, mg, ppk, sam
      8. 1669688Domain d1p7lc2: 1p7l C:103-231 [94302]
        complexed with anp, k, met, mg, ppk, sam
      9. 1669689Domain d1p7lc3: 1p7l C:232-383 [94303]
        complexed with anp, k, met, mg, ppk, sam
      10. 1669690Domain d1p7ld1: 1p7l D:1-102 [94304]
        complexed with anp, k, met, mg, ppk, sam
      11. 1669691Domain d1p7ld2: 1p7l D:103-231 [94305]
        complexed with anp, k, met, mg, ppk, sam
      12. 1669692Domain d1p7ld3: 1p7l D:232-383 [94306]
        complexed with anp, k, met, mg, ppk, sam
    6. Domains for 1rg9:
      1. 1669666Domain d1rg9a1: 1rg9 A:1-102 [97427]
        complexed with k, mg, ppk, sam
      2. 1669667Domain d1rg9a2: 1rg9 A:103-231 [97428]
        complexed with k, mg, ppk, sam
      3. 1669668Domain d1rg9a3: 1rg9 A:232-383 [97429]
        complexed with k, mg, ppk, sam
      4. 1669669Domain d1rg9b1: 1rg9 B:1-102 [97430]
        complexed with k, mg, ppk, sam
      5. 1669670Domain d1rg9b2: 1rg9 B:103-231 [97431]
        complexed with k, mg, ppk, sam
      6. 1669671Domain d1rg9b3: 1rg9 B:232-383 [97432]
        complexed with k, mg, ppk, sam
      7. 1669672Domain d1rg9c1: 1rg9 C:1-102 [97433]
        complexed with k, mg, ppk, sam
      8. 1669673Domain d1rg9c2: 1rg9 C:103-231 [97434]
        complexed with k, mg, ppk, sam
      9. 1669674Domain d1rg9c3: 1rg9 C:232-383 [97435]
        complexed with k, mg, ppk, sam
      10. 1669675Domain d1rg9d1: 1rg9 D:1-102 [97436]
        complexed with k, mg, ppk, sam
      11. 1669676Domain d1rg9d2: 1rg9 D:103-231 [97437]
        complexed with k, mg, ppk, sam
      12. 1669677Domain d1rg9d3: 1rg9 D:232-383 [97438]
        complexed with k, mg, ppk, sam
    7. Domains for 1xra:
      1. 1669693Domain d1xraa1: 1xra A:1-101 [41341]
        complexed with k, mg, po4
      2. 1669694Domain d1xraa2: 1xra A:108-231 [41342]
        complexed with k, mg, po4
      3. 1669695Domain d1xraa3: 1xra A:232-383 [41343]
        complexed with k, mg, po4
    8. Domains for 1xrb:
      1. 1669663Domain d1xrba1: 1xrb A:1-101 [41335]
        complexed with k, mg, po4
      2. 1669664Domain d1xrba2: 1xrb A:108-231 [41336]
        complexed with k, mg, po4
      3. 1669665Domain d1xrba3: 1xrb A:232-383 [41337]
        complexed with k, mg, po4
    9. Domains for 1xrc:
      1. 1669678Domain d1xrca1: 1xrc A:1-101 [41338]
        complexed with co, k, po4
      2. 1669679Domain d1xrca2: 1xrc A:108-231 [41339]
        complexed with co, k, po4
      3. 1669680Domain d1xrca3: 1xrc A:232-383 [41340]
        complexed with co, k, po4
  2. 1669702Human (Homo sapiens), isoform type-2 [TaxId:9606] [160759] (2 PDB entries)
    Uniprot P31153 126-251! Uniprot P31153 16-125! Uniprot P31153 252-395
    MAT2A
    1. Domains for 2p02:
      1. 1669703Domain d2p02a1: 2p02 A:38-147 [149132]
        complexed with cl, sam
      2. 1669704Domain d2p02a2: 2p02 A:148-273 [149133]
        complexed with cl, sam
      3. 1669705Domain d2p02a3: 2p02 A:274-417 [149134]
        complexed with cl, sam
    2. Domains for 4ktt:
      1. 1669706Domain d4ktta1: 4ktt A:15-115 [257811]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      2. 1669707Domain d4ktta2: 4ktt A:135-251 [257812]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      3. 1669708Domain d4ktta3: 4ktt A:252-395 [257813]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      4. 1669709Domain d4kttb1: 4ktt B:14-125 [257808]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      5. 1669710Domain d4kttb2: 4ktt B:126-251 [257809]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      6. 1669711Domain d4kttb3: 4ktt B:252-395 [257810]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      7. 1669712Domain d4kttc1: 4ktt C:15-115 [257805]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      8. 1669713Domain d4kttc2: 4ktt C:134-251 [257806]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      9. 1669714Domain d4kttc3: 4ktt C:252-395 [257807]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
      10. 1669715Domain d4kttd1: 4ktt D:16-125 [257814]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a1
        complexed with edo, mg, po4, sam
      11. 1669716Domain d4kttd2: 4ktt D:126-251 [257815]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a2
        complexed with edo, mg, po4, sam
      12. 1669717Domain d4kttd3: 4ktt D:252-395 [257816]
        Other proteins in same PDB: d4kttf_
        automated match to d2p02a3
        complexed with edo, mg, po4, sam
  3. 1669718Norway rat (Rattus norvegicus) [TaxId:10116] [55977] (5 PDB entries)
    1. Domains for 1o90:
      1. 1669731Domain d1o90a1: 1o90 A:17-116 [92650]
        complexed with k, lis, mg, po4
      2. 1669732Domain d1o90a2: 1o90 A:129-252 [92651]
        complexed with k, lis, mg, po4
      3. 1669733Domain d1o90a3: 1o90 A:253-396 [92652]
        complexed with k, lis, mg, po4
      4. 1669734Domain d1o90b1: 1o90 B:17-116 [92653]
        complexed with k, lis, mg, po4
      5. 1669735Domain d1o90b2: 1o90 B:129-252 [92654]
        complexed with k, lis, mg, po4
      6. 1669736Domain d1o90b3: 1o90 B:253-396 [92655]
        complexed with k, lis, mg, po4
    2. Domains for 1o92:
      1. 1669737Domain d1o92a1: 1o92 A:17-116 [92659]
        complexed with adp, amb, k, mg, po4
      2. 1669738Domain d1o92a2: 1o92 A:129-252 [92660]
        complexed with adp, amb, k, mg, po4
      3. 1669739Domain d1o92a3: 1o92 A:253-396 [92661]
        complexed with adp, amb, k, mg, po4
      4. 1669740Domain d1o92b1: 1o92 B:17-116 [92662]
        complexed with adp, amb, k, mg, po4
      5. 1669741Domain d1o92b2: 1o92 B:129-252 [92663]
        complexed with adp, amb, k, mg, po4
      6. 1669742Domain d1o92b3: 1o92 B:253-396 [92664]
        complexed with adp, amb, k, mg, po4
    3. Domains for 1o93:
      1. 1669743Domain d1o93a1: 1o93 A:17-116 [92665]
        complexed with atp, k, lis, mg, po4
      2. 1669744Domain d1o93a2: 1o93 A:129-252 [92666]
        complexed with atp, k, lis, mg, po4
      3. 1669745Domain d1o93a3: 1o93 A:253-396 [92667]
        complexed with atp, k, lis, mg, po4
      4. 1669746Domain d1o93b1: 1o93 B:17-116 [92668]
        complexed with atp, k, lis, mg, po4
      5. 1669747Domain d1o93b2: 1o93 B:129-252 [92669]
        complexed with atp, k, lis, mg, po4
      6. 1669748Domain d1o93b3: 1o93 B:253-396 [92670]
        complexed with atp, k, lis, mg, po4
    4. Domains for 1o9t:
      1. 1669725Domain d1o9ta1: 1o9t A:17-116 [92685]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      2. 1669726Domain d1o9ta2: 1o9t A:129-252 [92686]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      3. 1669727Domain d1o9ta3: 1o9t A:253-396 [92687]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      4. 1669728Domain d1o9tb1: 1o9t B:17-116 [92688]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      5. 1669729Domain d1o9tb2: 1o9t B:129-252 [92689]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
      6. 1669730Domain d1o9tb3: 1o9t B:253-396 [92690]
        complexed with both substrates ATP and methionine
        complexed with atp, k, met, mg, po4
    5. Domains for 1qm4:
      1. 1669719Domain d1qm4a1: 1qm4 A:17-116 [41350]
        complexed with amb, k, mg, so4
      2. 1669720Domain d1qm4a2: 1qm4 A:129-252 [41351]
        complexed with amb, k, mg, so4
      3. 1669721Domain d1qm4a3: 1qm4 A:253-396 [41352]
        complexed with amb, k, mg, so4
      4. 1669722Domain d1qm4b1: 1qm4 B:17-116 [41353]
        complexed with amb, k, mg, so4
      5. 1669723Domain d1qm4b2: 1qm4 B:129-252 [41354]
        complexed with amb, k, mg, so4
      6. 1669724Domain d1qm4b3: 1qm4 B:253-396 [41355]
        complexed with amb, k, mg, so4

More info for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase

Timeline for Protein S-adenosylmethionine synthetase from d.130.1.1: S-adenosylmethionine synthetase: