SCOPe 2.02: Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain

Lineage for Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

Proteins:

1. HSP90 [55876] (3 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55877] (22 PDB entries)

   2. Species Dog (Canis familiaris) [TaxId:9615] [103225] (22 PDB entries)
      Uniprot P41148 76-285; Endoplasmin, GRP94

   3. Species Human (Homo sapiens) [TaxId:9606] [55878] (60 PDB entries)
      Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223

2. automated matches [190229] (6 species)
   not a true protein

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187543] (7 PDB entries)

   2. Species Caenorhabditis elegans [TaxId:6239] [194727] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [187292] (42 PDB entries)

   4. Species Leishmania major [TaxId:347515] [195250] (1 PDB entry)

   5. Species Plasmodium falciparum [TaxId:36329] [189412] (1 PDB entry)

   6. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [189431] (2 PDB entries)

More info for Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain

Timeline for Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain:

• Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain appears in SCOPe 2.01
  
• Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain appears in SCOPe 2.03
  
• Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain appears in the current release, SCOPe 2.08