Class d: Alpha and beta proteins (a+b) [53931] (381 folds) |
Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily) contains large mixed beta-sheet |
Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) automatically mapped to Pfam PF00303 |
Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins) |
Protein Thymidylate synthase [55833] (7 species) |
Bacillus subtilis [TaxId:1423] [55836] (5 PDB entries) |
Domain d1b02a_: 1b02 A: [41035] complexed with c2f, ufp |
Domain d1bkoa_: 1bko A: [41036] |
Domain d1bkob_: 1bko B: [41037] |
Domain d1bkoc_: 1bko C: [41038] |
Domain d1bkod_: 1bko D: [41039] |
Domain d1bkpa_: 1bkp A: [41029] |
Domain d1bkpb_: 1bkp B: [41030] |
Domain d1bsfa_: 1bsf A: [41033] |
Domain d1bsfb_: 1bsf B: [41034] |
Domain d1bspa_: 1bsp A: [41031] complexed with po4 |
Domain d1bspb_: 1bsp B: [41032] complexed with po4 |
Bacteriophage T4 [TaxId:10665] [55837] (1 PDB entry) |
Domain d1tisa_: 1tis A: [41040] complexed with po4 |
Escherichia coli [TaxId:562] [55834] (64 PDB entries) |
Domain d1aiqa_: 1aiq A: [40967] complexed with cb3, ump; mutant |
Domain d1aiqb_: 1aiq B: [40968] complexed with cb3, ump; mutant |
Domain d1ajma_: 1ajm A: [40981] mutant |
Domain d1an5a_: 1an5 A: [40986] complexed with cb3, po4 |
Domain d1an5b_: 1an5 B: [40987] complexed with cb3, po4 |
Domain d1aoba_: 1aob A: [40969] complexed with ddu, fmt, po4 |
Domain d1axwa_: 1axw A: [40938] complexed with mtx, ump |
Domain d1axwb_: 1axw B: [40939] complexed with mtx, ump |
Domain d1bdua_: 1bdu A: [40955] complexed with dur, po4 |
Domain d1bida_: 1bid A: [40960] complexed with ump |
Domain d1bjga_: 1bjg A: [40977] complexed with tmf, ufp; mutant |
Domain d1bq1a_: 1bq1 A: [40965] complexed with cb3, ump; mutant |
Domain d1bq1b_: 1bq1 B: [40966] complexed with cb3, ump; mutant |
Domain d1bq2a_: 1bq2 A: [40971] complexed with po4; mutant |
Domain d1ddua_: 1ddu A: [40961] complexed with cb3, ddu, po4 |
Domain d1ddub_: 1ddu B: [40962] complexed with cb3, ddu, po4 |
Domain d1dnaa_: 1dna A: [40956] complexed with cb3, ump; mutant |
Domain d1dnab_: 1dna B: [40957] complexed with cb3, ump; mutant |
Domain d1ev5a_: 1ev5 A: [40935] complexed with so4; mutant |
Domain d1ev8a_: 1ev8 A: [40989] mutant |
Domain d1evfa_: 1evf A: [40932] complexed with so4; mutant |
Domain d1evga_: 1evg A: [40954] complexed with so4; mutant |
Domain d1f4ba_: 1f4b A: [40936] complexed with gol, so4 |
Domain d1f4ca_: 1f4c A: [40950] complexed with gol, so4, tp2 |
Domain d1f4cb_: 1f4c B: [40951] complexed with gol, so4, tp2 |
Domain d1f4da_: 1f4d A: [40972] complexed with gol, so4, tp2 |
Domain d1f4db_: 1f4d B: [40973] complexed with gol, so4, tp2 |
Domain d1f4ea_: 1f4e A: [40941] complexed with gol, so4, tpr |
Domain d1f4fa_: 1f4f A: [40946] complexed with so4, tp3 |
Domain d1f4fb_: 1f4f B: [40947] complexed with so4, tp3 |
Domain d1f4ga_: 1f4g A: [40933] complexed with gol, so4, tp4 |
Domain d1f4gb_: 1f4g B: [40934] complexed with gol, so4, tp4 |
Domain d1ffla_: 1ffl A: [40988] mutant |
Domain d1fwma_: 1fwm A: [90500] complexed with cb3, so4; mutant |
Domain d1fwmb_: 1fwm B: [90501] complexed with cb3, so4; mutant |
Domain d1jg0a_: 1jg0 A: [66659] complexed with ddt, ump |
Domain d1jg0b_: 1jg0 B: [66660] complexed with ddt, ump |
Domain d1jtqa_: 1jtq A: [63282] complexed with ly3, ump |
Domain d1jtqb_: 1jtq B: [63283] complexed with ly3, ump |
Domain d1jtua_: 1jtu A: [63284] complexed with lyb, ump |
Domain d1jtub_: 1jtu B: [63285] complexed with lyb, ump |
Domain d1juta_: 1jut A: [63301] complexed with lyd, ump |
Domain d1jutb_: 1jut B: [63302] complexed with lyd, ump |
Domain d1kcea_: 1kce A: [40944] complexed with cb3, ump; mutant |
Domain d1kceb_: 1kce B: [40945] complexed with cb3, ump; mutant |
Domain d1kzia_: 1kzi A: [73363] complexed with co3, dtt, dtu, gol, thg, ump |
Domain d1kzib_: 1kzi B: [73364] complexed with co3, dtt, dtu, gol, thg, ump |
Domain d1kzja_: 1kzj A: [73365] complexed with cb3, ump |
Domain d1kzjb_: 1kzj B: [73366] complexed with cb3, ump |
Domain d1kzjc_: 1kzj C: [73367] complexed with cb3, ump |
Domain d1kzjd_: 1kzj D: [73368] complexed with cb3, ump |
Domain d1kzje_: 1kzj E: [73369] complexed with cb3, ump |
Domain d1kzjf_: 1kzj F: [73370] complexed with cb3, ump |
Domain d1ncea_: 1nce A: [80401] complexed with cb3, ump |
Domain d1nceb_: 1nce B: [80402] complexed with cb3, ump |
Domain d1qqqa_: 1qqq A: [40931] complexed with so4; mutant |
Domain d1syna_: 1syn A: [40958] complexed with f89, ump |
Domain d1synb_: 1syn B: [40959] complexed with f89, ump |
Domain d1tdua_: 1tdu A: [40963] complexed with cb3, dur, po4 |
Domain d1tdub_: 1tdu B: [40964] complexed with cb3, dur, po4 |
Domain d1tjsa_: 1tjs A: [40976] complexed with po4 |
Domain d1tlca_: 1tlc A: [40942] complexed with dgp, f89 |
Domain d1tlcb_: 1tlc B: [40943] complexed with dgp, f89 |
Domain d1tlsa_: 1tls A: [40982] complexed with c2f, ufp |
Domain d1tlsb_: 1tls B: [40983] complexed with c2f, ufp |
Domain d1trga_: 1trg A: [40940] complexed with cb3, ump |
Domain d1tsda_: 1tsd A: [40948] complexed with bme, f89, ump |
Domain d1tsdb_: 1tsd B: [40949] complexed with bme, f89, ump |
Domain d1tsna_: 1tsn A: [40970] complexed with c2f, po4, ufp |
Domain d1tysa_: 1tys A: [40937] complexed with dhf, tmp |
Domain d1zpra_: 1zpr A: [40978] complexed with cb3, ump; mutant |
Domain d1zprb_: 1zpr B: [40979] complexed with cb3, ump; mutant |
Domain d2a9wa_: 2a9w A: [126456] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wb_: 2a9w B: [126457] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wc_: 2a9w C: [126458] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wd_: 2a9w D: [126459] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2bbqa_: 2bbq A: [40974] complexed with pfg, ump |
Domain d2bbqb_: 2bbq B: [40975] complexed with pfg, ump |
Domain d2ftna_: 2ftn A: [164466] automated match to d1an5a_ complexed with so4; mutant |
Domain d2ftox_: 2fto X: [164467] automated match to d1an5a_ complexed with cb3, po4, tmp; mutant |
Domain d2ftqa_: 2ftq A: [134076] automated match to d1an5a_ complexed with po4, so4 |
Domain d2g8xa_: 2g8x A: [164605] automated match to d1an5a_ complexed with co3, dtt, po4 |
Domain d2g8xb_: 2g8x B: [164606] automated match to d1an5a_ complexed with co3, dtt, po4 |
Domain d2kcea_: 2kce A: [40984] complexed with d16, ump |
Domain d2kceb_: 2kce B: [40985] complexed with d16, ump |
Domain d2tsca_: 2tsc A: [40952] complexed with cb3, ump |
Domain d2tscb_: 2tsc B: [40953] complexed with cb3, ump |
Domain d2veta_: 2vet A: [168497] automated match to d1aiqa_ protein/RNA complex; complexed with fmt, ump |
Domain d2vf0a_: 2vf0 A: [243863] automated match to d2veta_ protein/RNA complex; complexed with f89, ndu, so4 |
Domain d2vf0b_: 2vf0 B: [243864] automated match to d2veta_ protein/RNA complex; complexed with f89, ndu, so4 |
Domain d3b5ba_: 3b5b A: [172428] automated match to d1aiqa_ complexed with fmt, ndn, ndu |
Domain d3b5bb_: 3b5b B: [172429] automated match to d1aiqa_ complexed with fmt, ndn, ndu |
Domain d3b9ha_: 3b9h A: [172508] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, po4 |
Domain d3bfia_: 3bfi A: [172592] automated match to d1an5a_ protein/RNA complex; complexed with ndu, so4; mutant |
Domain d3bgxa_: 3bgx A: [172629] automated match to d1an5a_ protein/RNA complex; complexed with mef, so4, tmp; mutant |
Domain d3bhla_: 3bhl A: [172637] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, so4, thg |
Domain d3bhlb_: 3bhl B: [172638] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, so4, thg |
Domain d3bhra_: 3bhr A: [172642] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, po4, thg |
Domain d3tmsa_: 3tms A: [40980] complexed with po4; mutant |
Domain d4geva_: 4gev A: [192445] automated match to d2g8ma_ complexed with cb3, umc |
Domain d4gevb_: 4gev B: [192446] automated match to d2g8ma_ complexed with cb3, umc |
Domain d4iska_: 4isk A: [230059] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskb_: 4isk B: [230056] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskc_: 4isk C: [230058] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskd_: 4isk D: [230057] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iske_: 4isk E: [230060] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskf_: 4isk F: [230063] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskg_: 4isk G: [230061] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskh_: 4isk H: [230062] automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4knza_: 4knz A: [192989] automated match to d2g8oa_ complexed with cb3, na, umc |
Domain d4knzb_: 4knz B: [192990] automated match to d2g8oa_ complexed with cb3, na, umc |
Domain d4lrra_: 4lrr A: [228800] automated match to d1f4ba_ complexed with cf9, so4, ump |
Fungus (Pneumocystis carinii) [TaxId:4754] [55838] (2 PDB entries) |
Domain d1ci7a_: 1ci7 A: [41041] complexed with cb3, ump |
Domain d1ci7b_: 1ci7 B: [41042] complexed with cb3, ump |
Domain d1f28a_: 1f28 A: [59608] complexed with f89, ump |
Domain d1f28b_: 1f28 B: [59609] complexed with f89, ump |
Domain d1f28c_: 1f28 C: [59610] complexed with f89, ump |
Domain d1f28d_: 1f28 D: [59611] complexed with f89, ump |
Human (Homo sapiens) [TaxId:9606] [55840] (24 PDB entries) |
Domain d1hvya_: 1hvy A: [41049] complexed with bme, d16, ump |
Domain d1hvyb_: 1hvy B: [41050] complexed with bme, d16, ump |
Domain d1hvyc_: 1hvy C: [41051] complexed with bme, d16, ump |
Domain d1hvyd_: 1hvy D: [41052] complexed with bme, d16, ump |
Domain d1hw3a_: 1hw3 A: [41053] complexed with edo, so4 |
Domain d1hw4a_: 1hw4 A: [41054] complexed with edo, so4 |
Domain d1hzwa_: 1hzw A: [61464] complexed with po4 |
Domain d1hzwb_: 1hzw B: [61465] complexed with po4 |
Domain d1i00a_: 1i00 A: [61475] complexed with d16, ump |
Domain d1i00b_: 1i00 B: [61476] complexed with d16, ump |
Domain d1ju6a_: 1ju6 A: [63289] complexed with lya, po4, ump |
Domain d1ju6b_: 1ju6 B: [63290] complexed with lya, po4, ump |
Domain d1ju6c_: 1ju6 C: [63291] complexed with lya, po4, ump |
Domain d1ju6d_: 1ju6 D: [63292] complexed with lya, po4, ump |
Domain d1juja_: 1juj A: [63297] complexed with lya, ump |
Domain d1jujb_: 1juj B: [63298] complexed with lya, ump |
Domain d1jujc_: 1juj C: [63299] complexed with lya, ump |
Domain d1jujd_: 1juj D: [63300] complexed with lya, ump |
Domain d1ypva1: 1ypv A:26-310 [203218] automated match to d1hw3a_ complexed with po4 |
Domain d2onba_: 2onb A: [205332] automated match to d1hw3a_ complexed with 7pa, edo, so4 |
Domain d2rd8a_: 2rd8 A: [206084] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rd8b_: 2rd8 B: [206085] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdaa_: 2rda A: [206086] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdab_: 2rda B: [206087] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdac_: 2rda C: [206088] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdad_: 2rda D: [206089] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdae_: 2rda E: [206090] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d2rdaf_: 2rda F: [206091] automated match to d2aaza_ complexed with bme, po4; mutant |
Domain d3egyx_: 3egy X: [209502] automated match to d2aaza_ complexed with edo, so4 |
Domain d3ehix_: 3ehi X: [209503] automated match to d2aaza_ complexed with edo, so4 |
Domain d3h9ka_: 3h9k A: [210912] automated match to d2aaza_ complexed with edo, po4, ufp |
Domain d3h9kb_: 3h9k B: [210913] automated match to d2aaza_ complexed with edo, po4, ufp |
Domain d3h9kc_: 3h9k C: [210914] automated match to d2aaza_ complexed with edo, po4, ufp |
Domain d3h9kd_: 3h9k D: [210915] automated match to d2aaza_ complexed with edo, po4, ufp |
Domain d3h9ke_: 3h9k E: [210916] automated match to d2aaza_ complexed with edo, po4, ufp |
Domain d3hb8a_: 3hb8 A: [210970] automated match to d2aaza_ complexed with edo, po4, ump |
Domain d3hb8b_: 3hb8 B: [210971] automated match to d2aaza_ complexed with edo, po4, ump |
Domain d3hb8c_: 3hb8 C: [210972] automated match to d2aaza_ complexed with edo, po4, ump |
Domain d3hb8d_: 3hb8 D: [210973] automated match to d2aaza_ complexed with edo, po4, ump |
Domain d3hb8e_: 3hb8 E: [210974] automated match to d2aaza_ complexed with edo, po4, ump |
Domain d3n5ga_: 3n5g A: [213747] automated match to d2aaza_ complexed with so4 |
Domain d3ob7a_: 3ob7 A: [214286] automated match to d2aaza_ complexed with gsh, po4 |
Domain d3ob7b_: 3ob7 B: [214287] automated match to d2aaza_ complexed with gsh, po4 |
Domain d3ob7c_: 3ob7 C: [214288] automated match to d2aaza_ complexed with gsh, po4 |
Domain d3ob7d_: 3ob7 D: [214289] automated match to d2aaza_ complexed with gsh, po4 |
Domain d3ob7e_: 3ob7 E: [214290] automated match to d2aaza_ complexed with gsh, po4 |
Domain d4e28a_: 4e28 A: [220167] automated match to d2aaza_ complexed with 0mz, 9mz, so4 |
Domain d4g6wx_: 4g6w X: [221732] automated match to d2aaza_ complexed with pbx, so4 |
Domain d4gd7a_: 4gd7 A: [234462] automated match to d1hw3a_ complexed with edo, so4, tiy |
Domain d4gyha_: 4gyh A: [252352] automated match to d4eb4a_ complexed with so4 |
Domain d4h1ia_: 4h1i A: [252362] automated match to d4eb4a_ complexed with so4 |
Domain d4h1ib_: 4h1i B: [252363] automated match to d4eb4a_ complexed with so4 |
Domain d4h1ic_: 4h1i C: [252364] automated match to d4eb4a_ complexed with so4 |
Domain d4h1id_: 4h1i D: [252365] automated match to d4eb4a_ complexed with so4 |
Domain d4jefa_: 4jef A: [259067] automated match to d1hvya_ complexed with so4 |
Domain d4kpwa_: 4kpw A: [256891] automated match to d4eb4a_ complexed with edo, so4; mutant |
Lactobacillus casei [TaxId:1582] [55835] (51 PDB entries) |
Domain d1bo7a_: 1bo7 A: [40997] complexed with u; mutant |
Domain d1bo8a_: 1bo8 A: [40994] complexed with k, u; mutant |
Domain d1bp0a_: 1bp0 A: [40993] complexed with k, ump; mutant |
Domain d1bp6a_: 1bp6 A: [41000] complexed with k, ump; mutant |
Domain d1bpja_: 1bpj A: [40996] complexed with k, ump; mutant |
Domain d1jmfa_: 1jmf A: [41007] complexed with ump; mutant |
Domain d1jmga_: 1jmg A: [41008] complexed with ump; mutant |
Domain d1jmha_: 1jmh A: [41009] complexed with ump; mutant |
Domain d1jmia_: 1jmi A: [41006] complexed with ump; mutant |
Domain d1lcaa_: 1lca A: [41015] complexed with cb3, ump |
Domain d1lcba_: 1lcb A: [41028] complexed with dhf, tmp |
Domain d1lcea_: 1lce A: [41018] complexed with tmf, ump |
Domain d1njaa_: 1nja A: [40999] complexed with dcm; mutant |
Domain d1njba_: 1njb A: [41023] complexed with ump |
Domain d1njca_: 1njc A: [41005] complexed with dcm; mutant |
Domain d1njda_: 1njd A: [41004] complexed with ump; mutant |
Domain d1njea_: 1nje A: [41001] complexed with dcm |
Domain d1tdaa_: 1tda A: [41027] complexed with po4 |
Domain d1tdba_: 1tdb A: [41025] complexed with ufp |
Domain d1tdca_: 1tdc A: [41026] complexed with ump |
Domain d1thya_: 1thy A: [41010] complexed with ump |
Domain d1tsla_: 1tsl A: [40992] complexed with a15, po4 |
Domain d1tsma_: 1tsm A: [41024] complexed with mr2, po4 |
Domain d1tsva_: 1tsv A: [41019] complexed with ump; mutant |
Domain d1tswa_: 1tsw A: [40991] complexed with po4; mutant |
Domain d1tsxa_: 1tsx A: [41002] complexed with ump; mutant |
Domain d1tsya_: 1tsy A: [40990] complexed with ump; mutant |
Domain d1tsza_: 1tsz A: [41020] complexed with po4; mutant |
Domain d1tvua_: 1tvu A: [41012] complexed with cb3, ump; mutant |
Domain d1tvva_: 1tvv A: [40998] complexed with cb3, ump; mutant |
Domain d1tvwa_: 1tvw A: [41013] complexed with cb3, ump; mutant |
Domain d1vzaa_: 1vza A: [41017] complexed with ump; mutant |
Domain d1vzba_: 1vzb A: [41022] complexed with ump; mutant |
Domain d1vzca_: 1vzc A: [41016] complexed with ufp; mutant |
Domain d1vzda_: 1vzd A: [41014] complexed with cb3, ufp; mutant |
Domain d1vzea_: 1vze A: [41003] complexed with cb3, ump; mutant |
Domain d2g86a_: 2g86 A: [164598] automated match to d1bo7a_ complexed with ump |
Domain d2g89a_: 2g89 A: [164599] automated match to d1bo7a_ complexed with ump |
Domain d2g8aa_: 2g8a A: [164600] automated match to d1bo7a_ complexed with ump |
Domain d2g8da_: 2g8d A: [164602] automated match to d1bo7a_ complexed with ump |
Domain d2tdda_: 2tdd A: [41021] complexed with thf, ufp |
Domain d2tdma_: 2tdm A: [41011] complexed with ump |
Domain d3bnza_: 3bnz A: [172728] automated match to d1bo7a_ complexed with c16, po4, ump |
Domain d3byxa_: 3byx A: [172939] automated match to d1bo7a_ complexed with c00, ump |
Domain d3bz0a_: 3bz0 A: [172941] automated match to d1bo7a_ complexed with c00, ump |
Domain d3c06a_: 3c06 A: [172971] automated match to d1bo7a_ complexed with 14c, ump |
Domain d3c0aa_: 3c0a A: [172972] automated match to d1bo7a_ complexed with 14c, ump |
Domain d3ijza_: 3ijz A: [178357] automated match to d1bo7a_ complexed with 15c, ump |
Domain d3ik0a_: 3ik0 A: [178358] automated match to d1bo7a_ complexed with 7c1, ump |
Domain d3ik1a_: 3ik1 A: [178359] automated match to d1bo7a_ complexed with 20c, ump |
Domain d4tmsa_: 4tms A: [40995] complexed with po4; mutant |
Norway rat (Rattus norvegicus) [TaxId:10116] [55839] (2 PDB entries) |
Domain d1rtsa_: 1rts A: [41047] complexed with d16, ump |
Domain d1rtsb_: 1rts B: [41048] complexed with d16, ump |
Domain d2tsra_: 2tsr A: [41043] complexed with d16, ump |
Domain d2tsrb_: 2tsr B: [41044] complexed with d16, ump |
Domain d2tsrc_: 2tsr C: [41045] complexed with d16, ump |
Domain d2tsrd_: 2tsr D: [41046] complexed with d16, ump |
Timeline for Protein Thymidylate synthase from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase: