SCOP 1.71: Family d.109.1.2: Cofilin-like

Lineage for Family d.109.1.2: Cofilin-like

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.109: Gelsolin-like [55752] (2 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (2 families)

5. Family d.109.1.2: Cofilin-like [55762] (7 proteins)

Proteins:

1. Adf-H domain of twinfilin isoform-1 [82752] (1 species)
   interacts only with G-actin

   • Species Mouse (Mus musculus) [TaxId:10090] [82753] (1 PDB entry)

2. Coactosin-like protein Cotl1 (Clp) [111105] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [111107] (2 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [111106] (2 PDB entries)

3. Cofilin (actin depolymerizing factor, ADF) [55763] (4 species)

   1. Species Amoeba (Acanthamoeba castellanii), actophorin [55766] (2 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55765] (3 PDB entries)

   3. Species Human (Homo sapiens), non-muscle isoform [TaxId:9606] [111104] (2 PDB entries)

   4. Species Plant (Arabidopsis thaliana), ADF1 [TaxId:3702] [55764] (1 PDB entry)

4. Cofilin-like domain of actin-binding protein abp1p [69793] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69794] (1 PDB entry)

5. Destrin [55767] (1 species)

   • Species Human and pig (Homo sapiens) and (Sus scrofa) [TaxId:9606] [55768] (2 PDB entries)
     identical sequence in both species

6. Glia maturation factor beta, GMF-beta [111108] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [111109] (1 PDB entry)

7. Glia maturation factor gamma, GMF-gamma [111110] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [111111] (2 PDB entries)

More info for Family d.109.1.2: Cofilin-like

Timeline for Family d.109.1.2: Cofilin-like:

• Family d.109.1.2: Cofilin-like first appeared (with stable ids) in SCOP 1.55
  
• Family d.109.1.2: Cofilin-like appears in SCOP 1.69
  
• Family d.109.1.2: Cofilin-like appears in SCOP 1.73
  
• Family d.109.1.2: Cofilin-like appears in the current release, SCOPe 2.08