SCOPe 2.06: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.06
Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
Fold d.109: Gelsolin-like [55752] (3 superfamilies)
3 layers: a/b/a; contains mixed beta-sheet
Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families)
Family d.109.1.1: Gelsolin-like [55754] (5 proteins)
Protein Gelsolin [55759] (2 species)
consists of six similar domains
Species Human (Homo sapiens) [TaxId:9606] [55761] (39 PDB entries)
Uniprot P20065 55-179

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 1c0f:
- Domain d1c0fs_: 1c0f S: [40851]
  Other proteins in same PDB: d1c0fa1, d1c0fa2
  domain 1
  complexed with atp, ca
Domain(s) for 1c0g:
- Domain d1c0gs_: 1c0g S: [40848]
  Other proteins in same PDB: d1c0ga1, d1c0ga2
  domain 1
  complexed with atp, ca; mutant
Domain(s) for 1d4x:
- Domain d1d4xg_: 1d4x G: [59109]
  Other proteins in same PDB: d1d4xa1, d1d4xa2
  complexed with atp, ca, mg, so2, so4
Domain(s) for 1dej:
- Domain d1dejs_: 1dej S: [40850]
  Other proteins in same PDB: d1deja1, d1deja2
  domain 1
  complexed with atp, ca; mutant
Domain(s) for 1dga:
- Domain d1dgag_: 1dga G: [302331]
  Other proteins in same PDB: d1dgaa3, d1dgaa4
  automated match to d1yagg_
  complexed with atp, ca, mg, so4
Domain(s) for 1eqy:
- Domain d1eqys_: 1eqy S: [40853]
  Other proteins in same PDB: d1eqya1, d1eqya2
  complexed with atp, ca
Domain(s) for 1esv:
- Domain d1esvs_: 1esv S: [40852]
  Other proteins in same PDB: d1esva1, d1esva2
  complexed with atp, ca, lar
Domain(s) for 1h1v:
1. Domain d1h1vg1: 1h1v G:412-532 [76503]
  Other proteins in same PDB: d1h1va1, d1h1va2
  domains 4, 5 and 6
  complexed with atp, ca
2. Domain d1h1vg2: 1h1v G:533-628 [76504]
  Other proteins in same PDB: d1h1va1, d1h1va2
  domains 4, 5 and 6
  complexed with atp, ca
3. Domain d1h1vg3: 1h1v G:629-742 [76505]
  Other proteins in same PDB: d1h1va1, d1h1va2
  domains 4, 5 and 6
  complexed with atp, ca
Domain(s) for 1kcq:
- Domain d1kcqa_: 1kcq A: [68449]
  metal ion-binding domain 2
  complexed with cd
Domain(s) for 1mdu:
1. Domain d1mdua_: 1mdu A: [79014]
  Other proteins in same PDB: d1mdub1, d1mdub2, d1mdue1, d1mdue2
  domain 1
  complexed with atp, ca, trs
2. Domain d1mdud_: 1mdu D: [79017]
  Other proteins in same PDB: d1mdub1, d1mdub2, d1mdue1, d1mdue2
  domain 1
  complexed with atp, ca, trs
Domain(s) for 1nlv:
- Domain d1nlvg_: 1nlv G: [80632]
  Other proteins in same PDB: d1nlva1, d1nlva2
  domain 1
  complexed with atp, ca, so2, so4
Domain(s) for 1nm1:
- Domain d1nm1g_: 1nm1 G: [80653]
  Other proteins in same PDB: d1nm1a1, d1nm1a2
  domain 1
  complexed with atp, ca, mg, so2, so4
Domain(s) for 1nmd:
- Domain d1nmdg_: 1nmd G: [80658]
  Other proteins in same PDB: d1nmda1, d1nmda2
  domain 1
  complexed with atp, ca, so2, so4
Domain(s) for 1nph:
1. Domain d1npha1: 1nph A:414-532 [85956]
  domains 4, 5 and 6 in active, actin free conformation
  complexed with ca
2. Domain d1npha2: 1nph A:533-628 [85957]
  domains 4, 5 and 6 in active, actin free conformation
  complexed with ca
3. Domain d1npha3: 1nph A:629-742 [85958]
  domains 4, 5 and 6 in active, actin free conformation
  complexed with ca
Domain(s) for 1p8x:
1. Domain d1p8xa1: 1p8x A:412-532 [94365]
  domains 4, 5 and 6
  complexed with ca
2. Domain d1p8xa2: 1p8x A:533-628 [94366]
  domains 4, 5 and 6
  complexed with ca
3. Domain d1p8xa3: 1p8x A:629-741 [94367]
  domains 4, 5 and 6
  complexed with ca
4. Domain d1p8xb1: 1p8x B:414-532 [94368]
  domains 4, 5 and 6
  complexed with ca
5. Domain d1p8xb2: 1p8x B:533-628 [94369]
  domains 4, 5 and 6
  complexed with ca
6. Domain d1p8xb3: 1p8x B:629-741 [94370]
  domains 4, 5 and 6
  complexed with ca
7. Domain d1p8xc1: 1p8x C:414-532 [94371]
  domains 4, 5 and 6
  complexed with ca
8. Domain d1p8xc2: 1p8x C:533-628 [94372]
  domains 4, 5 and 6
  complexed with ca
9. Domain d1p8xc3: 1p8x C:629-741 [94373]
  domains 4, 5 and 6
  complexed with ca
Domain(s) for 1p8z:
- Domain d1p8zg_: 1p8z G: [94376]
  Other proteins in same PDB: d1p8za1, d1p8za2
  domain 1 with a domain 2 linker
  complexed with atp, ca, cd
Domain(s) for 1t44:
- Domain d1t44g_: 1t44 G: [106395]
  Other proteins in same PDB: d1t44a1, d1t44a2
  complexed with atp, ca
Domain(s) for 1yag:
- Domain d1yagg_: 1yag G: [40846]
  Other proteins in same PDB: d1yaga1, d1yaga2
  domain 1
  domain 1
  complexed with atp, ca, mg, so4
Domain(s) for 1yvn:
- Domain d1yvng_: 1yvn G: [40849]
  Other proteins in same PDB: d1yvna1, d1yvna2
  complexed with atp, ca, mg, so4; mutant
Domain(s) for 2fh1:
1. Domain d2fh1a1: 2fh1 A:412-532 [133441]
  automated match to d1p8xa1
  complexed with ca
2. Domain d2fh1a2: 2fh1 A:533-628 [133442]
  automated match to d1p8xa2
  complexed with ca
3. Domain d2fh1a3: 2fh1 A:629-741 [133443]
  automated match to d1p8xa3
  complexed with ca
4. Domain d2fh1b1: 2fh1 B:414-532 [133444]
  automated match to d1p8xa1
  complexed with ca
5. Domain d2fh1b2: 2fh1 B:533-628 [133445]
  automated match to d1p8xa2
  complexed with ca
6. Domain d2fh1b3: 2fh1 B:629-741 [133446]
  automated match to d1p8xa3
  complexed with ca
7. Domain d2fh1c1: 2fh1 C:414-532 [133447]
  automated match to d1p8xa1
  complexed with ca
8. Domain d2fh1c2: 2fh1 C:533-628 [133448]
  automated match to d1p8xa2
  complexed with ca
9. Domain d2fh1c3: 2fh1 C:629-741 [133449]
  automated match to d1p8xa3
  complexed with ca
Domain(s) for 2fh2:
1. Domain d2fh2a1: 2fh2 A:412-532 [133450]
  automated match to d1p8xa1
  complexed with ca
2. Domain d2fh2a2: 2fh2 A:533-628 [133451]
  automated match to d1p8xa2
  complexed with ca
3. Domain d2fh2a3: 2fh2 A:629-741 [133452]
  automated match to d1p8xa3
  complexed with ca
4. Domain d2fh2b1: 2fh2 B:414-532 [133453]
  automated match to d1p8xa1
  complexed with ca
5. Domain d2fh2b2: 2fh2 B:533-628 [133454]
  automated match to d1p8xa2
  complexed with ca
6. Domain d2fh2b3: 2fh2 B:629-741 [133455]
  automated match to d1p8xa3
  complexed with ca
7. Domain d2fh2c1: 2fh2 C:414-532 [133456]
  automated match to d1p8xa1
  complexed with ca
8. Domain d2fh2c2: 2fh2 C:533-628 [133457]
  automated match to d1p8xa2
  complexed with ca
9. Domain d2fh2c3: 2fh2 C:629-741 [133458]
  automated match to d1p8xa3
  complexed with ca
Domain(s) for 2fh3:
1. Domain d2fh3a1: 2fh3 A:412-532 [133459]
  automated match to d1p8xa1
  complexed with ca
2. Domain d2fh3a2: 2fh3 A:533-628 [133460]
  automated match to d1p8xa2
  complexed with ca
3. Domain d2fh3a3: 2fh3 A:629-741 [133461]
  automated match to d1p8xa3
  complexed with ca
4. Domain d2fh3b1: 2fh3 B:414-532 [133462]
  automated match to d1p8xa1
  complexed with ca
5. Domain d2fh3b2: 2fh3 B:533-628 [133463]
  automated match to d1p8xa2
  complexed with ca
6. Domain d2fh3b3: 2fh3 B:629-741 [133464]
  automated match to d1p8xa3
  complexed with ca
7. Domain d2fh3c1: 2fh3 C:414-532 [133465]
  automated match to d1p8xa1
  complexed with ca
8. Domain d2fh3c2: 2fh3 C:533-628 [133466]
  automated match to d1p8xa2
  complexed with ca
9. Domain d2fh3c3: 2fh3 C:629-741 [133467]
  automated match to d1p8xa3
  complexed with ca
Domain(s) for 3a5l:
- Domain d3a5ls_: 3a5l S: [171754]
  Other proteins in same PDB: d3a5lc1, d3a5lc2
  automated match to d1c0fs_
  complexed with adp, ca, mg
Domain(s) for 3a5m:
- Domain d3a5ms_: 3a5m S: [171755]
  Other proteins in same PDB: d3a5mc1, d3a5mc2
  automated match to d1c0fs_
  complexed with atp, ca, mg
Domain(s) for 3a5n:
- Domain d3a5ns_: 3a5n S: [171756]
  Other proteins in same PDB: d3a5nc1, d3a5nc2
  automated match to d1c0fs_
  complexed with atp, ca
Domain(s) for 3a5o:
- Domain d3a5os_: 3a5o S: [171757]
  Other proteins in same PDB: d3a5oc1, d3a5oc2
  automated match to d1c0fs_
  complexed with atp, ca
Domain(s) for 3ci5:
- Domain d3ci5g2: 3ci5 G:1-125 [156662]
  Other proteins in same PDB: d3ci5a1, d3ci5a2, d3ci5g3
  automated match to d1yagg_
  complexed with atp, ca, gol, mg, so4
Domain(s) for 3cip:
- Domain d3cipg2: 3cip G:1-125 [156678]
  Other proteins in same PDB: d3cipa1, d3cipa2, d3cipg3
  automated match to d1yagg_
  complexed with atp, ca, gol, mg, so4
Domain(s) for 3cjb:
- Domain d3cjbg1: 3cjb G:2-125 [156697]
  automatically matched to d1p8zg_
  complexed with atp, ca
Domain(s) for 3cjc:
- Domain d3cjcg1: 3cjc G:2-125 [156699]
  Other proteins in same PDB: d3cjcd1
  automatically matched to d1p8zg_
  complexed with atp, ca, so4
Domain(s) for 3ffk:
1. Domain d3ffka1: 3ffk A:28-152 [246107]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na1
  complexed with atp, ca
2. Domain d3ffka2: 3ffk A:153-262 [246108]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na2
  complexed with atp, ca
3. Domain d3ffka3: 3ffk A:263-374 [246109]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na3
  complexed with atp, ca
4. Domain d3ffkd1: 3ffk D:27-152 [246112]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na1
  complexed with atp, ca
5. Domain d3ffkd2: 3ffk D:153-262 [246113]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na2
  complexed with atp, ca
6. Domain d3ffkd3: 3ffk D:263-372 [246114]
  Other proteins in same PDB: d3ffkb1, d3ffkb2, d3ffke1, d3ffke2
  automated match to d1d0na3
  complexed with atp, ca
Domain(s) for 3ffn:
1. Domain d3ffna1: 3ffn A:23-152 [246117]
  automated match to d1d0na1
2. Domain d3ffna2: 3ffn A:153-258 [246118]
  automated match to d1d0na2
3. Domain d3ffna3: 3ffn A:264-383 [246119]
  automated match to d1d0na3
4. Domain d3ffna4: 3ffn A:384-532 [246120]
  automated match to d1d0na4
5. Domain d3ffna5: 3ffn A:533-628 [246121]
  automated match to d1d0na5
6. Domain d3ffna6: 3ffn A:629-755 [246122]
  automated match to d1d0na6
7. Domain d3ffnb1: 3ffn B:27-152 [246123]
  automated match to d1d0na1
8. Domain d3ffnb2: 3ffn B:153-258 [246124]
  automated match to d1d0na2
9. Domain d3ffnb3: 3ffn B:265-383 [246125]
  automated match to d1d0na3
10. Domain d3ffnb4: 3ffn B:384-532 [246126]
  automated match to d1d0na4
11. Domain d3ffnb5: 3ffn B:533-628 [246127]
  automated match to d1d0na5
12. Domain d3ffnb6: 3ffn B:629-755 [246128]
  automated match to d1d0na6
Domain(s) for 4s10:
1. Domain d4s10c_: 4s10 C: [273445]
  Other proteins in same PDB: d4s10a_, d4s10b_
  automated match to d1kcqa_
  complexed with ca; mutant
2. Domain d4s10d_: 4s10 D: [273444]
  Other proteins in same PDB: d4s10a_, d4s10b_
  automated match to d1kcqa_
  complexed with ca; mutant
Domain(s) for 5dd2:
1. Domain d5dd2a_: 5dd2 A: [323714]
  automated match to d1p8zg_
  complexed with ca, pg0
2. Domain d5dd2g_: 5dd2 G: [323536]
  automated match to d1p8zg_
  complexed with ca, pg0
Domain(s) for 5faf:
- Domain d5fafa1: 5faf A:151-260 [323569]
  Other proteins in same PDB: d5fafa2
  automated match to d1kcqa_
  complexed with act, ca, cl, gol
Domain(s) for 5h3m:
- Domain d5h3ma_: 5h3m A: [340861]
  automated match to d1p8zg_
Domain(s) for 5h3n:
- Domain d5h3na_: 5h3n A: [340866]
  automated match to d1p8zg_
Domain(s) for 5o2z:
1. Domain d5o2za_: 5o2z A: [341278]
  Other proteins in same PDB: d5o2zb2
  automated match to d1kcqa_
  complexed with act, ca, flc, gol, na
2. Domain d5o2zb1: 5o2z B:151-258 [341270]
  Other proteins in same PDB: d5o2zb2
  automated match to d1kcqa_
  complexed with act, ca, flc, gol, na
Domain(s) for 5ubo:
- Domain d5ubos_: 5ubo S: [343246]
  Other proteins in same PDB: d5uboa1, d5uboa2
  automated match to d1p8zg_
  complexed with atp, ca, mpd

More info for Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin:

Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin appears in SCOPe 2.05
Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin appears in SCOPe 2.07
Species Human (Homo sapiens) [TaxId:9606] from d.109.1.1 Gelsolin appears in the current release, SCOPe 2.08