Lineage for Protein: N-myristoyl transferase, NMT

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.108: Acyl-CoA N-acyltransferases (Nat) [55728] (1 superfamily)
    3 layers: a/b/a; contains mixed beta-sheet
  4. Superfamily d.108.1: Acyl-CoA N-acyltransferases (Nat) [55729] (12 families) (S)
  5. Family d.108.1.2: N-myristoyl transferase, NMT [55748] (1 protein)
    duplication: consists of two NAT-like domains swapped with the C-terminal strands
  6. Protein N-myristoyl transferase, NMT [55749] (4 species)

Species:

  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55750] (3 PDB entries)
    1. Domains for 1iic:
      1. Domain d1iica1: 1iic A:34-218 [62422]
        complexed with mya
      2. Domain d1iica2: 1iic A:219-455 [62423]
        complexed with mya
      3. Domain d1iicb1: 1iic B:34-218 [62424]
        complexed with mya
      4. Domain d1iicb2: 1iic B:219-455 [62425]
        complexed with mya
    2. Domains for 1iid:
      1. Domain d1iida1: 1iid A:34-218 [62426]
        complex with s-(2-oxo)pentadecyl-CoA and the octapeptide
        complexed with nhm, ni
      2. Domain d1iida2: 1iid A:219-455 [62427]
        complex with s-(2-oxo)pentadecyl-CoA and the octapeptide
        complexed with nhm, ni
    3. Domains for 2nmt:
      1. Domain d2nmta1: 2nmt A:34-218 [40821]
        complexed with gol, mim, nhm
      2. Domain d2nmta2: 2nmt A:219-455 [40822]
        complexed with gol, mim, nhm
  2. Human (Homo sapiens) [TaxId:9606] [143710] (1 PDB entry)
    Uniprot P30419 155-294! Uniprot P30419 295-496
  3. Plasmodium vivax [TaxId:5855] [346374] (2 PDB entries)
    1. Domains for 5g1z:
      1. Domain d5g1za2: 5g1z A:211-410 [344221]
        Other proteins in same PDB: d5g1za1, d5g1zb1, d5g1zc1
        complexed with cl, dms, mg, nhw, so4, u53
      2. Domain d5g1zb2: 5g1z B:211-410 [344222]
        Other proteins in same PDB: d5g1za1, d5g1zb1, d5g1zc1
        complexed with cl, dms, mg, nhw, so4, u53
      3. Domain d5g1zc2: 5g1z C:211-410 [344223]
        Other proteins in same PDB: d5g1za1, d5g1zb1, d5g1zc1
        complexed with cl, dms, mg, nhw, so4, u53
    2. Domains for 5g22:
      1. Domain d5g22a2: 5g22 A:211-410 [344224]
        Other proteins in same PDB: d5g22a1, d5g22b1, d5g22c1
        complexed with cl, mg, nhw, so4, yn4
      2. Domain d5g22b2: 5g22 B:211-410 [344225]
        Other proteins in same PDB: d5g22a1, d5g22b1, d5g22c1
        complexed with cl, mg, nhw, so4, yn4
      3. Domain d5g22c2: 5g22 C:211-410 [344226]
        Other proteins in same PDB: d5g22a1, d5g22b1, d5g22c1
        complexed with cl, mg, nhw, so4, yn4
  4. Yeast (Candida albicans) [TaxId:5476] [55751] (3 PDB entries)
    1. Domains for 1iyk:
      1. Domain d1iyka1: 1iyk A:60-224 [76958]
        complexed with mim, mya
      2. Domain d1iyka2: 1iyk A:225-451 [76959]
        complexed with mim, mya
      3. Domain d1iykb1: 1iyk B:60-224 [76960]
        complexed with mim, mya
      4. Domain d1iykb2: 1iyk B:225-451 [76961]
        complexed with mim, mya
    2. Domains for 1iyl:
      1. Domain d1iyla1: 1iyl A:68-224 [76962]
        complexed with r64
      2. Domain d1iyla2: 1iyl A:225-451 [76963]
        complexed with r64
      3. Domain d1iylb1: 1iyl B:72-224 [76964]
        complexed with r64
      4. Domain d1iylb2: 1iyl B:225-451 [76965]
        complexed with r64
      5. Domain d1iylc1: 1iyl C:71-224 [76966]
        complexed with r64
      6. Domain d1iylc2: 1iyl C:225-451 [76967]
        complexed with r64
      7. Domain d1iyld1: 1iyl D:72-224 [76968]
        complexed with r64
      8. Domain d1iyld2: 1iyl D:225-451 [76969]
        complexed with r64
    3. Domains for 1nmt:
      1. Domain d1nmta1: 1nmt A:60-224 [40823]
        complexed with gol
      2. Domain d1nmta2: 1nmt A:225-451 [40824]
        complexed with gol
      3. Domain d1nmtb1: 1nmt B:60-224 [40825]
        complexed with gol
      4. Domain d1nmtb2: 1nmt B:225-451 [40826]
        complexed with gol
      5. Domain d1nmtc1: 1nmt C:60-224 [40827]
        complexed with gol
      6. Domain d1nmtc2: 1nmt C:225-451 [40828]
        complexed with gol

More info for Protein N-myristoyl transferase, NMT from d.108.1.2: N-myristoyl transferase, NMT

Timeline for Protein N-myristoyl transferase, NMT from d.108.1.2: N-myristoyl transferase, NMT: