Lineage for Family d.108.1.1: N-acetyl transferase, NAT

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 730983Fold d.108: Acyl-CoA N-acyltransferases (Nat) [55728] (1 superfamily)
    3 layers: a/b/a; contains mixed beta-sheet
  4. 730984Superfamily d.108.1: Acyl-CoA N-acyltransferases (Nat) [55729] (9 families) (S)
  5. 730985Family d.108.1.1: N-acetyl transferase, NAT [55730] (56 proteins)

Proteins:

  1. 730986Aminoglycoside 2'-N-acetyltransferase [75506] (1 species)
  2. 730996Aminoglycoside 3-N-acetyltransferase [55733] (1 species)
  3. 731000Aminoglycoside 6'-N-acetyltransferase [55731] (1 species)
  4. 731009Aminoglycoside N-acetyltransferase AAC(6')-IY [111098] (1 species)
  5. 731016Catalytic domain of GCN5 histone acetyltransferase [55737] (3 species)
    1. 731017Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55738] (1 PDB entry)
    2. 731020Species Human (Homo sapiens) [TaxId:9606] [143647] (1 PDB entry)
    3. 731022Species Tetrahymena thermophila [TaxId:5911] [55739] (9 PDB entries)
  6. 731033Diamine acetyltransferase 1 [143652] (1 species)
  7. 731053Diamine acetyltransferase 2 [143688] (1 species)
  8. 731059Glucosamine-phosphate N-acetyltransferase GNA1 [64351] (1 species)
  9. 731075Histone acetyltransferase domain of P300/CBP associating factor, PCAF [55735] (1 species)
  10. 731079Histone acetyltransferase ESA1 [55744] (1 species)
    most similar to HAT1 including the N- and C-terminal (sub)domains; the N-terminal domain contains a rudiment CCHC zinc-finger (res. 191-220); the C-terminal domain (res. 351-434) has "winged helix" DNA-binding fold
  11. 731085Histone acetyltransferase HAT1 [55742] (1 species)
    contains additional N- and C-terminal (sub)domains
  12. 731088Histone acetyltransferase HPA2 [55740] (1 species)
  13. 731098Histone acetyltransferase MYST3 [143702] (1 species)
    ESA1 orthologue
    • 731099Species Human (Homo sapiens) [TaxId:9606] [143703] (1 PDB entry)
      solution structure of the zinc-binding motif have been determined in isolation (PDB 1m36, scop_sp 103600)
  14. 731101Hypothetical protein AT1g77540 [118064] (1 species)
  15. 731106Hypothetical protein MW0638 [143690] (1 species)
    SA0631 ortholog
  16. 731109Hypothetical protein PA0115 [118066] (1 species)
  17. 731119Hypothetical protein PA3270 [143686] (1 species)
  18. 731125Hypothetical protein PA4866 [143694] (1 species)
    Putative phosphinothricin acetyltransferase
  19. 731130Hypothetical protein PH0736 [143666] (1 species)
  20. 731134Hypothetical protein PH1933 [143648] (1 species)
  21. 731138Hypothetical protein Rv1347c/MT1389 [143668] (1 species)
  22. 731148Hypothetical protein SA2161 [143674] (1 species)
  23. 731152Hypothetical protein SA2309 [103173] (1 species)
  24. 731156Hypothetical protein YqiY [90013] (1 species)
  25. 731160Hypothetical protein YsnE [143654] (1 species)
  26. 731163Hypothetical protein YvbK (BSu33890) [143706] (1 species)
  27. 731169IAA acetyltransferase [143696] (1 species)
    YvbK ortholojg
  28. 731175L7/L12-Ribosomal-protein-serine acetyltransferase RimL [143678] (1 species)
  29. 731186Mycothiol synthase MshD [103175] (1 species)
    duplication: consists of two NAT domains swapped with the C-terminal strands with both domains binding acetyl-CoA; structural link with the other families
  30. 731191Phosphinothricin acetyltransferase [143698] (1 species)
  31. 731197Probable acetyltranferase Atu2435 [143704] (1 species)
  32. 731200Probable acetyltransferase Atu2258 [143656] (1 species)
  33. 731203Probable acetyltransferase Atu2290 [143660] (1 species)
  34. 731209Probable acetyltransferase BC2806 [143650] (1 species)
  35. 731213Probable acetyltransferase EF1919 [143662] (1 species)
  36. 731217Probable acetyltransferase PA4026 [143692] (1 species)
  37. 731223Probable acetyltransferase SP0256 [143680] (1 species)
    probable SA2161 ortholog
  38. 731226Probable acetyltransferase TTHA1209 [118068] (1 species)
  39. 731232Probable acetyltransferase YdaF [90015] (1 species)
  40. 731240Probable acetyltransferase YitI [143670] (1 species)
  41. 731243Probable acetyltransferase YjcF [103169] (1 species)
  42. 731246Probable histone acetyltransferase MYST1 [143672] (1 species)
    ESA1 orthologue
  43. 731249Probable N-acetyltransferase PA0478 [143676] (1 species)
  44. 731253Probable N-acetyltransferase RPA1999 [143708] (1 species)
  45. 731256Probable spermine/spermidine acetyltransferase EF1086 [143682] (1 species)
  46. 731259Protease synthase and sporulation negative regulatory protein PaiA [111100] (1 species)
  47. 731263Putative acetyltransferase EF0244 [143664] (1 species)
  48. 731269Putative acetyltransferase EF0945 [118070] (1 species)
  49. 731275Putative acetyltransferase PA4794 [143700] (1 species)
  50. 731278Putative acetyltransferase PF0028 [118072] (1 species)
  51. 731282Putative acetyltransferase YycN [90011] (1 species)
  52. 731290Putative phosphinothricin acetyltransferase YwnH [103171] (1 species)
  53. 731294Putative ribosomal-protein-serine acetyltransferase VC1889 [143684] (1 species)
    similar to RimL and RimJ
  54. 731297Serotonin N-acetyltranferase [55746] (1 species)
  55. 731310Tabtoxin resistance protein [82747] (1 species)
    possesses HAT activity
  56. 731316Transcriptional regulator BH1968 [143658] (1 species)

More info for Family d.108.1.1: N-acetyl transferase, NAT

Timeline for Family d.108.1.1: N-acetyl transferase, NAT: