SCOP 1.75: Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain

Lineage for Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.105: Subdomain of clathrin and coatomer appendage domain [55710] (1 superfamily)
   beta-alpha-beta-alpha-beta(4)-alpha; 3 layers: a/b/a; bifurcated antiparallel beta-sheet

4. Superfamily d.105.1: Subdomain of clathrin and coatomer appendage domain [55711] (2 families)

5. Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain [55712] (2 proteins)

Proteins:

1. Alpa-adaptin AP2, C-terminal subdomain [55713] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [55714] (10 PDB entries)
     Uniprot P17427 694-938 # 98% sequence identity

2. Beta2-adaptin AP2, C-terminal subdomain [55715] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [55716] (4 PDB entries)

More info for Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain

Timeline for Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain:

• Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain first appeared (with stable ids) in SCOP 1.55, called Family d.105.1.1: Clathrin adaptor appendage domain
  
• Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain appears in SCOP 1.73
  
• Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain appears in SCOPe 2.01
  
• Family d.105.1.1: Clathrin adaptor appendage, alpha and beta chain-specific domain appears in the current release, SCOPe 2.08