SCOPe 2.01: Family d.101.1.1: Ribonuclease PH domain 2-like

Lineage for Family d.101.1.1: Ribonuclease PH domain 2-like

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.101: Ribonuclease PH domain 2-like [55665] (1 superfamily)
   beta(2)-alpha-beta(2)-alpha; 3 layers: alpha/beta/alpha; antiparallel sheet: order 2134

4. Superfamily d.101.1: Ribonuclease PH domain 2-like [55666] (1 family)

5. Family d.101.1.1: Ribonuclease PH domain 2-like [55667] (10 proteins)

Proteins:

1. Exosome complex exonuclease 1, ECX1 [160590] (2 species)

   1. Species Archaeoglobus fulgidus [TaxId:2234] [160592] (2 PDB entries)
      Uniprot O29757 154-252

   2. Species Sulfolobus solfataricus [TaxId:2287] [160591] (7 PDB entries)
      Uniprot Q9UXC2 156-241! Uniprot Q9UXC2 156-248

2. Exosome complex exonuclease 2, ECX2 [160597] (2 species)

   1. Species Archaeoglobus fulgidus [TaxId:2234] [160598] (2 PDB entries)
      Uniprot O29756 179-257

   2. Species Sulfolobus solfataricus [TaxId:2287] [160599] (7 PDB entries)
      Uniprot Q9UXC0 192-275

3. Exosome complex exonuclease MTR3 [160600] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160601] (1 PDB entry)
     Uniprot Q5RKV6 176-270

4. Exosome complex exonuclease RRP41 [160593] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160594] (1 PDB entry)
     Uniprot Q9NPD3 152-241

5. Exosome complex exonuclease RRP42 [160588] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160589] (1 PDB entry)
     Uniprot Q15024 192-285

6. Exosome complex exonuclease RRP43 [160602] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160603] (1 PDB entry)
     Uniprot Q96B26 188-276

7. Exosome complex exonuclease RRP45 [160586] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160587] (1 PDB entry)
     Uniprot Q86Y41 185-302

8. Exosome complex exonuclease RRP46 [160595] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160596] (1 PDB entry)
     Uniprot Q9NQT4 147-235

9. Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 [55668] (1 species)
   duplication of two-domain units formed by domains 1-2 and 4-5

   • Species Streptomyces antibioticus [TaxId:1890] [55669] (2 PDB entries)

10. Ribonuclease PH, domain 2 [103150] (3 species)

    1. Species Aquifex aeolicus [TaxId:63363] [103151] (4 PDB entries)

    2. Species Bacillus subtilis [TaxId:1423] [103153] (3 PDB entries)

    3. Species Pseudomonas aeruginosa [TaxId:287] [103152] (2 PDB entries)

More info for Family d.101.1.1: Ribonuclease PH domain 2-like

Timeline for Family d.101.1.1: Ribonuclease PH domain 2-like:

• Family d.101.1.1: Ribonuclease PH domain 2-like first appeared (with stable ids) in SCOP 1.55, called Family d.101.1.1: Polynucleotide phosporylase/guanosine pentaphospate synthase (PNPase/GPSI), domains 2 and 5
  
• Family d.101.1.1: Ribonuclease PH domain 2-like appears in SCOP 1.75
  
• Family d.101.1.1: Ribonuclease PH domain 2-like appears in SCOPe 2.02
  
• Family d.101.1.1: Ribonuclease PH domain 2-like appears in the current release, SCOPe 2.08