Lineage for Protein: Urate oxidase (uricase)

  1. Root: SCOP 1.69
  2. 496776Class d: Alpha and beta proteins (a+b) [53931] (279 folds)
  3. 508755Fold d.96: T-fold [55619] (1 superfamily)
    beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
    tunnel-shaped: its known members form wide oligomeric barrels different sizes
  4. 508756Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (4 families) (S)
    bind purine or pterin in topologically similar sites between subunits
  5. 508960Family d.96.1.4: Urate oxidase (uricase) [55633] (1 protein)
  6. 508961Protein Urate oxidase (uricase) [55634] (2 species)
    duplication: one subunit consists of two domains of this fold; beta-sheets of two subunits form a barrel, closed: n=16, S=16

Species:

  1. 508962Aspergillus flavus [TaxId:5059] [55635] (4 PDB entries)
    1. Domains for 1r4s:
      1. 508967Domain d1r4sa1: 1r4s A:1-136 [97045]
      2. 508968Domain d1r4sa2: 1r4s A:137-296 [97046]
    2. Domains for 1r4u:
      1. 508965Domain d1r4ua1: 1r4u A:1-136 [97047]
      2. 508966Domain d1r4ua2: 1r4u A:137-295 [97048]
    3. Domains for 1r51:
      1. 508963Domain d1r51a1: 1r51 A:1-136 [97057]
      2. 508964Domain d1r51a2: 1r51 A:137-296 [97058]
    4. Domains for 1r56:
      1. 508969Domain d1r56a1: 1r56 A:1-136 [97064]
      2. 508970Domain d1r56a2: 1r56 A:137-295 [97065]
      3. 508971Domain d1r56b1: 1r56 B:1-136 [97066]
      4. 508972Domain d1r56b2: 1r56 B:137-295 [97067]
      5. 508973Domain d1r56c1: 1r56 C:1-136 [97068]
      6. 508974Domain d1r56c2: 1r56 C:137-299 [97069]
      7. 508975Domain d1r56d1: 1r56 D:1-136 [97070]
      8. 508976Domain d1r56d2: 1r56 D:137-295 [97071]
      9. 508977Domain d1r56e1: 1r56 E:1-136 [97072]
      10. 508978Domain d1r56e2: 1r56 E:137-295 [97073]
      11. 508979Domain d1r56f1: 1r56 F:1-136 [97074]
      12. 508980Domain d1r56f2: 1r56 F:137-295 [97075]
      13. 508981Domain d1r56g1: 1r56 G:1-136 [97076]
      14. 508982Domain d1r56g2: 1r56 G:137-296 [97077]
      15. 508983Domain d1r56h1: 1r56 H:1-136 [97078]
      16. 508984Domain d1r56h2: 1r56 H:137-295 [97079]
  2. 508985Bacillus sp., strain TB-90 [TaxId:1409] [111089] (1 PDB entry)

More info for Protein Urate oxidase (uricase) from d.96.1.4: Urate oxidase (uricase)

Timeline for Protein Urate oxidase (uricase) from d.96.1.4: Urate oxidase (uricase):