Lineage for Family d.96.1.4: Urate oxidase (uricase)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.96: T-fold [55619] (2 superfamilies)
    beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
    tunnel-shaped: its known members form wide oligomeric barrels different sizes
  4. Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (5 families) (S)
    bind purine or pterin in topologically similar sites between subunits
  5. Family d.96.1.4: Urate oxidase (uricase) [55633] (2 proteins)
    automatically mapped to Pfam PF01014

Proteins:

  1. Urate oxidase (uricase) [55634] (3 species)
    duplication: one subunit consists of two domains of this fold; beta-sheets of two subunits form a barrel, closed: n=16, S=16
    1. Species Arthrobacter globiformis [TaxId:1665] [143630] (2 PDB entries)
    2. Species Aspergillus flavus [TaxId:5059] [55635] (71 PDB entries)
    3. Species Bacillus sp., strain TB-90 [TaxId:1409] [111089] (1 PDB entry)
      Uniprot Q45697 177-482
  2. automated matches [254656] (4 species)
    not a true protein
    1. Species Arthrobacter globiformis [TaxId:1665] [255720] (5 PDB entries)
    2. Species Aspergillus flavus [TaxId:5059] [260668] (5 PDB entries)
    3. Species Bacillus sp. [TaxId:36824] [312567] (12 PDB entries)
    4. Species Bacillus tb-90 [TaxId:36824] [280497] (1 PDB entry)

More info for Family d.96.1.4: Urate oxidase (uricase)

Timeline for Family d.96.1.4: Urate oxidase (uricase):