SCOPe 2.06: Protein: 7,8-dihydroneopterin aldolase

Lineage for Protein: 7,8-dihydroneopterin aldolase

Root: SCOPe 2.06
Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
Fold d.96: T-fold [55619] (2 superfamilies)
beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
tunnel-shaped: its known members form wide oligomeric barrels different sizes
Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (5 families)
bind purine or pterin in topologically similar sites between subunits
Family d.96.1.3: DHN aldolase/epimerase [55628] (3 proteins)
beta-sheets of four subunits form a barrel, closed: n=16, S=16
automatically mapped to Pfam PF02152
Protein 7,8-dihydroneopterin aldolase [55629] (4 species)

Species:

Bacillus anthracis [TaxId:261594] [280019] (1 PDB entry)
- Domains for 5f3m:
  1. Domain d5f3ma1: 5f3m A:2-120 [280023]
    Other proteins in same PDB: d5f3ma2, d5f3mb2
    automated match to d1dhna_
    complexed with cl, edo, fmt, neu, ni
  2. Domain d5f3mb1: 5f3m B:2-120 [280020]
    Other proteins in same PDB: d5f3ma2, d5f3mb2
    automated match to d1dhna_
    complexed with cl, edo, fmt, neu, ni
Mycobacterium tuberculosis [TaxId:1773] [103143] (2 PDB entries)
Uniprot O06275 2-115
1. Domains for 1nbu:
  1. Domain d1nbua_: 1nbu A: [91767]
    complexed with ph2
  2. Domain d1nbub_: 1nbu B: [91768]
    complexed with ph2
  3. Domain d1nbuc_: 1nbu C: [91769]
    complexed with ph2
  4. Domain d1nbud_: 1nbu D: [91770]
    complexed with ph2
  5. Domain d1nbue_: 1nbu E: [91771]
    complexed with ph2
  6. Domain d1nbuf_: 1nbu F: [91772]
    complexed with ph2
  7. Domain d1nbug_: 1nbu G: [91773]
    complexed with ph2
  8. Domain d1nbuh_: 1nbu H: [91774]
    complexed with ph2
2. Domain for 1z9w:
  - Domain d1z9wa_: 1z9w A: [124772]
    automated match to d1nbua_
Staphylococcus aureus [TaxId:1280] [55630] (13 PDB entries)
Uniprot P56740
1. Domain for 1dhn:
  - Domain d1dhna_: 1dhn A: [40663]
2. Domain for 1rr5:
  - Domain d1rr5a_: 1rr5 A: [303029]
    automated match to d1dhna_
    complexed with npr
3. Domain for 1rri:
  - Domain d1rria_: 1rri A: [97797]
    complexed with a45
4. Domain for 1rrw:
  - Domain d1rrwa_: 1rrw A: [97804]
    complexed with 9mg
5. Domain for 1rry:
  - Domain d1rrya_: 1rry A: [97805]
    complexed with 204
6. Domain for 1rs2:
  - Domain d1rs2a_: 1rs2 A: [97806]
    complexed with 209
7. Domain for 1rs4:
  - Domain d1rs4a_: 1rs4 A: [97807]
    complexed with 45p
8. Domain for 1rsd:
  - Domain d1rsda_: 1rsd A: [97808]
    complexed with psb
9. Domain for 1rsi:
  - Domain d1rsia_: 1rsi A: [97810]
    complexed with 977
10. Domain for 1u68:
  - Domain d1u68a_: 1u68 A: [113060]
    complexed with npr
11. Domain for 2dhn:
  - Domain d2dhna_: 2dhn A: [40664]
    complexed with ph2
12. Domains for 2nm2:
  1. Domain d2nm2a_: 2nm2 A: [148286]
    automated match to d1dhna_
    complexed with neu
  2. Domain d2nm2b_: 2nm2 B: [148287]
    automated match to d1dhna_
    complexed with neu
  3. Domain d2nm2c_: 2nm2 C: [148288]
    automated match to d1dhna_
    complexed with neu
  4. Domain d2nm2d_: 2nm2 D: [148289]
    automated match to d1dhna_
    complexed with neu
13. Domain for 2nm3:
  - Domain d2nm3a_: 2nm3 A: [148290]
    automated match to d1dhna_
    complexed with act, mpu
Thale cress (Arabidopsis thaliana) [TaxId:3702] [111088] (1 PDB entry)
Uniprot Q9SF23
- Domains for 1sql:
  1. Domain d1sqla_: 1sql A: [105925]
    complexed with gun
  2. Domain d1sqlb_: 1sql B: [105926]
    complexed with gun
  3. Domain d1sqlc_: 1sql C: [105927]
    complexed with gun
  4. Domain d1sqld_: 1sql D: [105928]
    complexed with gun
  5. Domain d1sqle_: 1sql E: [105929]
    complexed with gun
  6. Domain d1sqlf_: 1sql F: [105930]
    complexed with gun
  7. Domain d1sqlg_: 1sql G: [105931]
    complexed with gun
  8. Domain d1sqlh_: 1sql H: [105932]
    complexed with gun
  9. Domain d1sqli_: 1sql I: [105933]
    complexed with gun
  10. Domain d1sqlj_: 1sql J: [105934]
    complexed with gun
  11. Domain d1sqlk_: 1sql K: [105935]
    complexed with gun
  12. Domain d1sqll_: 1sql L: [105936]
    complexed with gun
  13. Domain d1sqlm_: 1sql M: [105937]
    complexed with gun
  14. Domain d1sqln_: 1sql N: [105938]
    complexed with gun
  15. Domain d1sqlo_: 1sql O: [105939]
    complexed with gun
  16. Domain d1sqlp_: 1sql P: [105940]
    complexed with gun

More info for Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase

Timeline for Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase:

Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase first appeared (with stable ids) in SCOP 1.55, called Protein 7,8-dihidroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase
Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase appears in SCOPe 2.05
Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase appears in SCOPe 2.07
Protein 7,8-dihydroneopterin aldolase from d.96.1.3: DHN aldolase/epimerase appears in the current release, SCOPe 2.08