SCOP 1.67: Family d.96.1.3: DHN aldolase/epimerase

Lineage for Family d.96.1.3: DHN aldolase/epimerase

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.96: T-fold [55619] (1 superfamily)
   beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
   tunnel-shaped: its known members form wide oligomeric barrels different sizes

4. Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (4 families)
   bind purine or pterin in topologically similar sites between subunits

5. Family d.96.1.3: DHN aldolase/epimerase [55628] (2 proteins)
   beta-sheets of four subunits form a barrel, closed: n=16, S=16

Proteins:

1. 7,8-dihydroneopterin aldolase [55629] (2 species)

   1. Species Bacteria (Mycobacterium tuberculosis) [TaxId:1773] [103143] (1 PDB entry)

   2. Species Staphylococcus aureus [TaxId:1280] [55630] (10 PDB entries)

2. 7,8-dihydroneopterin triphosphate epimerase [55631] (1 species)

   • Species Escherichia coli [TaxId:562] [55632] (1 PDB entry)

More info for Family d.96.1.3: DHN aldolase/epimerase

Timeline for Family d.96.1.3: DHN aldolase/epimerase:

• Family d.96.1.3: DHN aldolase/epimerase first appeared (with stable ids) in SCOP 1.55
  
• Family d.96.1.3: DHN aldolase/epimerase appears in SCOP 1.65
  
• Family d.96.1.3: DHN aldolase/epimerase appears in SCOP 1.69
  
• Family d.96.1.3: DHN aldolase/epimerase appears in the current release, SCOPe 2.08