Lineage for Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like

  1. Root: SCOP 1.71
  2. 595667Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
  3. 608476Fold d.96: T-fold [55619] (1 superfamily)
    beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
    tunnel-shaped: its known members form wide oligomeric barrels different sizes
  4. 608477Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (4 families) (S)
    bind purine or pterin in topologically similar sites between subunits

Families:

  1. 608478d.96.1.1: GTP cyclohydrolase I [55621] (1 protein)
  2. 608623d.96.1.2: 6-pyruvoyl tetrahydropterin synthase [55625] (1 protein)
  3. 608636d.96.1.3: DHN aldolase/epimerase [55628] (2 proteins)
    beta-sheets of four subunits form a barrel, closed: n=16, S=16
  4. 608686d.96.1.4: Urate oxidase (uricase) [55633] (1 protein)

More info for Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like

Timeline for Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like: