SCOPe 2.05: Fold d.96: T-fold

Lineage for Fold d.96: T-fold

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.96: T-fold [55619] (2 superfamilies)
   beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
   tunnel-shaped: its known members form wide oligomeric barrels different sizes

Superfamilies:

1. d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (5 families)
   bind purine or pterin in topologically similar sites between subunits

2. d.96.2: ApbE-like [143631] (2 families)
   duplication: contains two differently decorated beta(2)-alpha(2)-beta(2) subdomains, similar to other T-fold domains; probably does not form the tunnel-shaped oligomers

More info for Fold d.96: T-fold

Timeline for Fold d.96: T-fold:

• Fold d.96: T-fold first appeared (with stable ids) in SCOP 1.55
  
• Fold d.96: T-fold appears in SCOPe 2.04
  
• Fold d.96: T-fold appears in SCOPe 2.06
  
• Fold d.96: T-fold appears in the current release, SCOPe 2.08