SCOPe 2.04: Family d.95.2.2: Intein endonuclease

Lineage for Family d.95.2.2: Intein endonuclease

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.95: Homing endonuclease-like [55603] (2 superfamilies)
   alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

4. Superfamily d.95.2: Homing endonucleases [55608] (3 families)

5. Family d.95.2.2: Intein endonuclease [55614] (2 proteins)
   duplication: contains tandem repeat of this fold

Proteins:

1. PI-Pfui intein [55617] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [55618] (1 PDB entry)

2. VMA1-derived endonuclease (VDE) PI-SceI [55615] (1 species)
   homing endonuclease with protein splicing activity

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55616] (7 PDB entries)
     Uniprot P17255 284-737

More info for Family d.95.2.2: Intein endonuclease

Timeline for Family d.95.2.2: Intein endonuclease:

• Family d.95.2.2: Intein endonuclease first appeared (with stable ids) in SCOP 1.55
  
• Family d.95.2.2: Intein endonuclease appears in SCOPe 2.03
  
• Family d.95.2.2: Intein endonuclease appears in SCOPe 2.05
  
• Family d.95.2.2: Intein endonuclease appears in the current release, SCOPe 2.08