Lineage for Protein: Phosphatidylinositol 3-kinase, p85-alpha subunit

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 868294Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. 868295Superfamily d.93.1: SH2 domain [55550] (1 family) (S)
  5. 868296Family d.93.1.1: SH2 domain [55551] (34 proteins)
    Pfam PF00017
  6. 868536Protein Phosphatidylinositol 3-kinase, p85-alpha subunit [55569] (3 species)

Species:

  1. 868537Cow (Bos taurus) [TaxId:9913] [55570] (7 PDB entries)
    1. Domain for 1bfi:
    2. Domain for 1bfj:
    3. Domain for 1oo3:
    4. Domain for 1oo4:
      • 868541Domain d1oo4a_: 1oo4 A: [87185]
        N-terminal SH2 domain; complexed to a peptide derived from PDGFR (chain B)
        complexed with ptr; mutant
    5. Domain for 1qad:
    6. Domain for 2pna:
    7. Domain for 2pnb:
  2. 868545Human (Homo sapiens) [TaxId:9606] [55571] (2 PDB entries)
    1. Domain for 1h9o:
      • 868546Domain d1h9oa_: 1h9o A: [60837]
        complexed with a tyr751 phosphopeptide from the pdgf receptor
    2. Domain for 1pic:
  3. 868548Rat (Rattus norvegicus) [TaxId:10116] [55572] (2 PDB entries)
    1. Domain for 1fu5:
    2. Domain for 1fu6:

More info for Protein Phosphatidylinositol 3-kinase, p85-alpha subunit from d.93.1.1: SH2 domain

Timeline for Protein Phosphatidylinositol 3-kinase, p85-alpha subunit from d.93.1.1: SH2 domain: