Lineage for Family d.93.1.1: SH2 domain

  1. Root: SCOP 1.67
  2. 405194Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
  3. 415905Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. 415906Superfamily d.93.1: SH2 domain [55550] (1 family) (S)
  5. 415907Family d.93.1.1: SH2 domain [55551] (28 proteins)

Proteins:

  1. 415908Abl tyrosine kinase [55581] (2 species)
    1. 415909Species Human (Homo sapiens) [TaxId:9606] [55582] (1 PDB entry)
    2. 415911Species Mouse (Mus musculus) [TaxId:10090] [89998] (2 PDB entries)
  2. 415915Adaptor protein Aps [103139] (1 species)
  3. 415921c-src tyrosine kinase [55556] (3 species)
    1. 415922Species Chicken (Gallus gallus) [TaxId:9031] [55558] (3 PDB entries)
    2. 415926Species Human (Homo sapiens) [TaxId:9606] [55557] (40 PDB entries)
    3. 415974Species Rous sarcoma virus [TaxId:11886] [69782] (12 PDB entries)
  4. 415996Carboxyl-terminal src kinase (csk) [75498] (1 species)
  5. 416004Cbl [55587] (1 species)
  6. 416011Crk proto-oncogen [82741] (1 species)
  7. 416014Csk homologous kinase Chk [64345] (1 species)
  8. 416017Ews/fli1 activated transcript 2, Eat2 [89999] (1 species)
  9. 416020Growth factor receptor-bound protein 10, GRB10 [89994] (1 species)
  10. 416024Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)
  11. 416055Growth factor receptor-bound protein 7 [103135] (1 species)
  12. 416058Hemopoetic cell kinase Hck [55565] (1 species)
  13. 416066Itk/tsk protein tyrosine kinase [82743] (1 species)
  14. 416072P55 Blk protein tyrosine kinase [55579] (1 species)
  15. 416076p56-lck tyrosine kinase [55552] (1 species)
  16. 416091Phosphatidylinositol 3-kinase, p85-alpha subunit [55569] (3 species)
    1. 416092Species Cow (Bos taurus) [TaxId:9913] [55570] (7 PDB entries)
    2. 416100Species Human (Homo sapiens) [TaxId:9606] [55571] (2 PDB entries)
    3. 416103Species Rat (Rattus norvegicus) [TaxId:10116] [55572] (2 PDB entries)
  17. 416106Phospholipase C-gamma-1 [55577] (1 species)
  18. 416110Proto-oncogen tyrosine kinase [55573] (1 species)
  19. 416113Shc adaptor protein [55567] (1 species)
  20. 416117STAT homologue [103137] (1 species)
  21. 416121STAT-1 [55583] (1 species)
  22. 416124STAT3b [55585] (1 species)
  23. 416127Syk tyrosine kinase [55575] (1 species)
  24. 416143The Xlp protein Sap [55591] (1 species)
  25. 416155Tyrosine kinase Fyn [55559] (1 species)
  26. 416161Tyrosine phoshatase shp-2 [55589] (1 species)
  27. 416167Tyrosine phosphatase Syp [55561] (1 species)
  28. 416174Tyrosine-protein kinase zap-70 [89996] (1 species)

More info for Family d.93.1.1: SH2 domain

Timeline for Family d.93.1.1: SH2 domain: