SCOPe 2.08: Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain

Lineage for Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (11 proteins)

Proteins:

1. Apoptosis-inducing factor (AIF) [75489] (2 species)
   contains a large loop insertion in this domain

   1. Species Human (Homo sapiens) [TaxId:9606] [75490] (2 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [75491] (1 PDB entry)

2. Dihydrolipoamide dehydrogenase [55436] (8 species)

   1. Species Azotobacter vinelandii [TaxId:354] [55439] (1 PDB entry)

   2. Species Bacillus stearothermophilus [TaxId:1422] [55440] (1 PDB entry)

   3. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64331] (2 PDB entries)

   4. Species Mycobacterium tuberculosis [TaxId:1773] [118041] (1 PDB entry)
      Uniprot O53355

   5. Species Neisseria meningitidis [TaxId:487] [55441] (2 PDB entries)

   6. Species Pea (Pisum sativum) [TaxId:3888] [55442] (1 PDB entry)

   7. Species Pseudomonas fluorescens [TaxId:294] [55438] (1 PDB entry)

   8. Species Pseudomonas putida [TaxId:303] [55437] (1 PDB entry)

3. Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit [55443] (1 species)
   rudiment "interface" domain of smaller size; beta(3)-alpha

   • Species Chromatium vinosum [TaxId:1049] [55444] (1 PDB entry)

4. Glutathione reductase [55426] (3 species)

   1. Species Escherichia coli [TaxId:562] [55428] (4 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [55427] (23 PDB entries)

   3. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [89990] (1 PDB entry)

5. Mammalian thioredoxin reductase [64329] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [64330] (1 PDB entry)

6. NADH oxidase /nitrite reductase [118042] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [118043] (1 PDB entry)
     Uniprot Q8U1K9

7. NADH peroxidase [55432] (1 species)

   • Species Enterococcus faecalis [TaxId:1351] [55433] (8 PDB entries)

8. NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase [82726] (1 species)

   • Species Xanthobacter sp., py2 [TaxId:35809] [82727] (5 PDB entries)

9. NADH-dependent ferredoxin reductase, BphA4 [55434] (1 species)

   • Species Pseudomonas sp., KKS102 [TaxId:306] [55435] (9 PDB entries)

10. Putidaredoxin reductase [103115] (1 species)

    • Species Pseudomonas putida [TaxId:303] [103116] (2 PDB entries)

11. Trypanothione reductase [55429] (3 species)

    1. Species Crithidia fasciculata [TaxId:5656] [55430] (6 PDB entries)

    2. Species Leishmania infantum [TaxId:5671] [267749] (1 PDB entry)

    3. Species Trypanosoma cruzi [TaxId:5693] [55431] (4 PDB entries)

More info for Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain

Timeline for Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain:

• Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain first appeared (with stable ids) in SCOP 1.55
  
• Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain appears in SCOPe 2.07