SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Fold d.83: Aha1/BPI domain-like

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2182658Fold d.83: Aha1/BPI domain-like [55393] (2 superfamilies)
    core: [beta]-alpha-beta(5)-alpha; 2 layers: alpha/beta; antiparallel beta-sheet, meander

Superfamilies:

  1. 2182659d.83.1: Bactericidal permeability-increasing protein, BPI [55394] (2 families) (S)
    duplication: consists of two clear structural repeats of this fold also containing an extra C-terminal beta-hairpin
  2. 2182674d.83.2: Activator of Hsp90 ATPase, Aha1 [103111] (1 family) (S)
    consists of a single domain of this fold
    automatically mapped to Pfam PF09229

More info for Fold d.83: Aha1/BPI domain-like

Timeline for Fold d.83: Aha1/BPI domain-like: