Lineage for Protein: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 259192Fold d.81: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55346] (1 superfamily)
    core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1
  4. 259193Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families) (S)
    N-terminal domain is the classic Rossmann-fold
  5. 259194Family d.81.1.1: GAPDH-like [55348] (2 proteins)
    has many additional secondary structures
  6. 259205Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (13 species)

Species:

  1. 259206Archaeon Methanothermus fervidus [TaxId:2180] [55355] (1 PDB entry)
  2. 259211Archaeon Sulfolobus solfataricus [TaxId:2287] [55354] (1 PDB entry)
  3. 259214Bacillus stearothermophilus, nca 1503 [TaxId:1422] [55351] (6 PDB entries)
    1. Domains for 1dbv:
      1. 259219Domain d1dbvo2: 1dbv O:149-312 [39881]
        Other proteins in same PDB: d1dbvo1, d1dbvp1, d1dbvq1, d1dbvr1
      2. 259220Domain d1dbvp2: 1dbv P:149-312 [39882]
        Other proteins in same PDB: d1dbvo1, d1dbvp1, d1dbvq1, d1dbvr1
      3. 259221Domain d1dbvq2: 1dbv Q:149-312 [39883]
        Other proteins in same PDB: d1dbvo1, d1dbvp1, d1dbvq1, d1dbvr1
      4. 259222Domain d1dbvr2: 1dbv R:149-312 [39884]
        Other proteins in same PDB: d1dbvo1, d1dbvp1, d1dbvq1, d1dbvr1
        complexed with nad, so4; mutant
    2. Domains for 1gd1:
      1. 259215Domain d1gd1o2: 1gd1 O:149-312 [39877]
        Other proteins in same PDB: d1gd1o1, d1gd1p1, d1gd1q1, d1gd1r1
      2. 259216Domain d1gd1p2: 1gd1 P:149-312 [39878]
        Other proteins in same PDB: d1gd1o1, d1gd1p1, d1gd1q1, d1gd1r1
      3. 259217Domain d1gd1q2: 1gd1 Q:149-312 [39879]
        Other proteins in same PDB: d1gd1o1, d1gd1p1, d1gd1q1, d1gd1r1
      4. 259218Domain d1gd1r2: 1gd1 R:149-312 [39880]
        Other proteins in same PDB: d1gd1o1, d1gd1p1, d1gd1q1, d1gd1r1
        complexed with nad, so4
    3. Domains for 2dbv:
      1. 259223Domain d2dbvo2: 2dbv O:149-312 [39885]
        Other proteins in same PDB: d2dbvo1, d2dbvp1, d2dbvq1, d2dbvr1
      2. 259224Domain d2dbvp2: 2dbv P:149-312 [39886]
        Other proteins in same PDB: d2dbvo1, d2dbvp1, d2dbvq1, d2dbvr1
      3. 259225Domain d2dbvq2: 2dbv Q:149-312 [39887]
        Other proteins in same PDB: d2dbvo1, d2dbvp1, d2dbvq1, d2dbvr1
      4. 259226Domain d2dbvr2: 2dbv R:149-312 [39888]
        Other proteins in same PDB: d2dbvo1, d2dbvp1, d2dbvq1, d2dbvr1
        complexed with ndp, so4; mutant
    4. Domains for 2gd1:
      1. 259231Domain d2gd1o2: 2gd1 O:149-312 [39893]
        Other proteins in same PDB: d2gd1o1, d2gd1p1, d2gd1q1, d2gd1r1
      2. 259232Domain d2gd1p2: 2gd1 P:149-312 [39894]
        Other proteins in same PDB: d2gd1o1, d2gd1p1, d2gd1q1, d2gd1r1
      3. 259233Domain d2gd1q2: 2gd1 Q:149-312 [39895]
        Other proteins in same PDB: d2gd1o1, d2gd1p1, d2gd1q1, d2gd1r1
      4. 259234Domain d2gd1r2: 2gd1 R:149-312 [39896]
        Other proteins in same PDB: d2gd1o1, d2gd1p1, d2gd1q1, d2gd1r1
        complexed with so4
    5. Domains for 3dbv:
      1. 259235Domain d3dbvo2: 3dbv O:149-312 [39897]
        Other proteins in same PDB: d3dbvo1, d3dbvp1, d3dbvq1, d3dbvr1
      2. 259236Domain d3dbvp2: 3dbv P:149-312 [39898]
        Other proteins in same PDB: d3dbvo1, d3dbvp1, d3dbvq1, d3dbvr1
      3. 259237Domain d3dbvq2: 3dbv Q:149-312 [39899]
        Other proteins in same PDB: d3dbvo1, d3dbvp1, d3dbvq1, d3dbvr1
      4. 259238Domain d3dbvr2: 3dbv R:149-312 [39900]
        Other proteins in same PDB: d3dbvo1, d3dbvp1, d3dbvq1, d3dbvr1
        complexed with nad, so4; mutant
    6. Domains for 4dbv:
      1. 259227Domain d4dbvo2: 4dbv O:149-312 [39889]
        Other proteins in same PDB: d4dbvo1, d4dbvp1, d4dbvq1, d4dbvr1
      2. 259228Domain d4dbvp2: 4dbv P:149-312 [39890]
        Other proteins in same PDB: d4dbvo1, d4dbvp1, d4dbvq1, d4dbvr1
      3. 259229Domain d4dbvq2: 4dbv Q:149-312 [39891]
        Other proteins in same PDB: d4dbvo1, d4dbvp1, d4dbvq1, d4dbvr1
      4. 259230Domain d4dbvr2: 4dbv R:149-312 [39892]
        Other proteins in same PDB: d4dbvo1, d4dbvp1, d4dbvq1, d4dbvr1
        complexed with ndp, so4; mutant
  4. 259239Escherichia coli [TaxId:562] [55350] (6 PDB entries)
    1. Domains for 1dc3:
      1. 259248Domain d1dc3a2: 1dc3 A:149-312 [39873]
        Other proteins in same PDB: d1dc3a1, d1dc3b1
      2. 259249Domain d1dc3b2: 1dc3 B:149-312 [39874]
        Other proteins in same PDB: d1dc3a1, d1dc3b1
    2. Domains for 1dc4:
      1. 259250Domain d1dc4a2: 1dc4 A:149-312 [39875]
        Other proteins in same PDB: d1dc4a1, d1dc4b1
      2. 259251Domain d1dc4b2: 1dc4 B:149-312 [39876]
        Other proteins in same PDB: d1dc4a1, d1dc4b1
        complexed with g3h
    3. Domains for 1dc5:
      1. 259242Domain d1dc5a2: 1dc5 A:149-312 [39867]
        Other proteins in same PDB: d1dc5a1, d1dc5b1
      2. 259243Domain d1dc5b2: 1dc5 B:149-312 [39868]
        Other proteins in same PDB: d1dc5a1, d1dc5b1
    4. Domains for 1dc6:
      1. 259244Domain d1dc6a2: 1dc6 A:149-312 [39871]
        Other proteins in same PDB: d1dc6a1, d1dc6b1
      2. 259245Domain d1dc6b2: 1dc6 B:149-312 [39872]
        Other proteins in same PDB: d1dc6a1, d1dc6b1
        complexed with nad
    5. Domains for 1gad:
      1. 259240Domain d1gado2: 1gad O:149-312 [39865]
        Other proteins in same PDB: d1gado1, d1gadp1
      2. 259241Domain d1gadp2: 1gad P:149-312 [39866]
        Other proteins in same PDB: d1gado1, d1gadp1
        complexed with nad
    6. Domains for 1gae:
      1. 259246Domain d1gaeo2: 1gae O:149-312 [39869]
        Other proteins in same PDB: d1gaeo1, d1gaep1
      2. 259247Domain d1gaep2: 1gae P:149-312 [39870]
        Other proteins in same PDB: d1gaeo1, d1gaep1
        complexed with nad; mutant
  5. 259252Human (Homo sapiens) [TaxId:9606] [55360] (1 PDB entry)
  6. 259255Leishmania mexicana [TaxId:5665] [55357] (5 PDB entries)
    1. Domains for 1a7k:
      1. 259266Domain d1a7ka2: 1a7k A:166-334 [39923]
        Other proteins in same PDB: d1a7ka1, d1a7kb1, d1a7kc1, d1a7kd1
      2. 259267Domain d1a7kb2: 1a7k B:166-334 [39924]
        Other proteins in same PDB: d1a7ka1, d1a7kb1, d1a7kc1, d1a7kd1
      3. 259268Domain d1a7kc2: 1a7k C:166-334 [39925]
        Other proteins in same PDB: d1a7ka1, d1a7kb1, d1a7kc1, d1a7kd1
      4. 259269Domain d1a7kd2: 1a7k D:166-334 [39926]
        Other proteins in same PDB: d1a7ka1, d1a7kb1, d1a7kc1, d1a7kd1
        complexed with nad, po4
    2. Domains for 1gyp:
      1. 259262Domain d1gypa2: 1gyp A:166-334 [39919]
        Other proteins in same PDB: d1gypa1, d1gypb1, d1gypc1, d1gypd1
      2. 259263Domain d1gypb2: 1gyp B:166-334 [39920]
        Other proteins in same PDB: d1gypa1, d1gypb1, d1gypc1, d1gypd1
      3. 259264Domain d1gypc2: 1gyp C:166-334 [39921]
        Other proteins in same PDB: d1gypa1, d1gypb1, d1gypc1, d1gypd1
      4. 259265Domain d1gypd2: 1gyp D:166-334 [39922]
        Other proteins in same PDB: d1gypa1, d1gypb1, d1gypc1, d1gypd1
        complexed with nad, po4
    3. Domains for 1gyq:
      1. 259276Domain d1gyqa2: 1gyq A:166-334 [39927]
        Other proteins in same PDB: d1gyqa1, d1gyqb1, d1gyqc1, d1gyqd1
      2. 259277Domain d1gyqb2: 1gyq B:166-334 [39928]
        Other proteins in same PDB: d1gyqa1, d1gyqb1, d1gyqc1, d1gyqd1
      3. 259278Domain d1gyqc2: 1gyq C:166-334 [39929]
        Other proteins in same PDB: d1gyqa1, d1gyqb1, d1gyqc1, d1gyqd1
      4. 259279Domain d1gyqd2: 1gyq D:166-334 [39930]
        Other proteins in same PDB: d1gyqa1, d1gyqb1, d1gyqc1, d1gyqd1
        complexed with nbd
    4. Domains for 1i32:
      1. 259256Domain d1i32a2: 1i32 A:166-334 [65994]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
      2. 259257Domain d1i32b2: 1i32 B:166-334 [65996]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
      3. 259258Domain d1i32c2: 1i32 C:166-334 [65998]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
      4. 259259Domain d1i32d2: 1i32 D:166-334 [66000]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
      5. 259260Domain d1i32e2: 1i32 E:166-334 [66002]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
      6. 259261Domain d1i32f2: 1i32 F:166-334 [66004]
        Other proteins in same PDB: d1i32a1, d1i32b1, d1i32c1, d1i32d1, d1i32e1, d1i32f1
        complexed with nmd
    5. Domains for 1i33:
      1. 259270Domain d1i33a2: 1i33 A:166-334 [66006]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
      2. 259271Domain d1i33b2: 1i33 B:166-334 [66008]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
      3. 259272Domain d1i33c2: 1i33 C:166-334 [66010]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
      4. 259273Domain d1i33d2: 1i33 D:166-334 [66012]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
      5. 259274Domain d1i33e2: 1i33 E:166-334 [66014]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
      6. 259275Domain d1i33f2: 1i33 F:166-334 [66016]
        Other proteins in same PDB: d1i33a1, d1i33b1, d1i33c1, d1i33d1, d1i33e1, d1i33f1
        complexed with tnd
  7. 259280Lobster (Homarus americanus) [55358] (2 PDB entries)
    1. Domains for 1gpd:
      1. 259285Domain d1gpdg2: 1gpd G:149-312 [39935]
        Other proteins in same PDB: d1gpdg1, d1gpdr1
      2. 259286Domain d1gpdr2: 1gpd R:149-312 [39936]
        Other proteins in same PDB: d1gpdg1, d1gpdr1
        complexed with ips, nad, sps
    2. Domains for 4gpd:
      1. 259281Domain d4gpd12: 4gpd 1:148-311 [39931]
        Other proteins in same PDB: d4gpd11, d4gpd21, d4gpd31, d4gpd41
      2. 259282Domain d4gpd22: 4gpd 2:148-311 [39932]
        Other proteins in same PDB: d4gpd11, d4gpd21, d4gpd31, d4gpd41
      3. 259283Domain d4gpd32: 4gpd 3:148-311 [39933]
        Other proteins in same PDB: d4gpd11, d4gpd21, d4gpd31, d4gpd41
      4. 259284Domain d4gpd42: 4gpd 4:148-311 [39934]
        Other proteins in same PDB: d4gpd11, d4gpd21, d4gpd31, d4gpd41
  8. 259287Lobster (Palinurus versicolor) [55359] (5 PDB entries)
    1. Domains for 1crw:
      1. 259290Domain d1crwg2: 1crw G:149-312 [39941]
        Other proteins in same PDB: d1crwg1, d1crwr1
      2. 259291Domain d1crwr2: 1crw R:149-312 [39942]
        Other proteins in same PDB: d1crwg1, d1crwr1
    2. Domains for 1dss:
      1. 259288Domain d1dssg2: 1dss G:149-312 [39937]
        Other proteins in same PDB: d1dssg1, d1dssr1
      2. 259289Domain d1dssr2: 1dss R:149-312 [39938]
        Other proteins in same PDB: d1dssg1, d1dssr1
        complexed with nad, so4
    3. Domains for 1ihx:
      1. 259294Domain d1ihxa2: 1ihx A:149-312 [71212]
        Other proteins in same PDB: d1ihxa1, d1ihxb1, d1ihxc1, d1ihxd1
      2. 259295Domain d1ihxb2: 1ihx B:149-312 [71214]
        Other proteins in same PDB: d1ihxa1, d1ihxb1, d1ihxc1, d1ihxd1
      3. 259296Domain d1ihxc2: 1ihx C:149-312 [71216]
        Other proteins in same PDB: d1ihxa1, d1ihxb1, d1ihxc1, d1ihxd1
      4. 259297Domain d1ihxd2: 1ihx D:149-312 [71218]
        Other proteins in same PDB: d1ihxa1, d1ihxb1, d1ihxc1, d1ihxd1
        complexed with snd, so4
    4. Domains for 1ihy:
      1. 259298Domain d1ihya2: 1ihy A:149-312 [71220]
        Other proteins in same PDB: d1ihya1, d1ihyb1, d1ihyc1, d1ihyd1
      2. 259299Domain d1ihyb2: 1ihy B:149-312 [71222]
        Other proteins in same PDB: d1ihya1, d1ihyb1, d1ihyc1, d1ihyd1
      3. 259300Domain d1ihyc2: 1ihy C:149-312 [71224]
        Other proteins in same PDB: d1ihya1, d1ihyb1, d1ihyc1, d1ihyd1
      4. 259301Domain d1ihyd2: 1ihy D:149-312 [71226]
        Other proteins in same PDB: d1ihya1, d1ihyb1, d1ihyc1, d1ihyd1
        complexed with apr, so4
    5. Domains for 1szj:
      1. 259292Domain d1szjg2: 1szj G:149-312 [39939]
        Other proteins in same PDB: d1szjg1, d1szjr1
      2. 259293Domain d1szjr2: 1szj R:149-312 [39940]
        Other proteins in same PDB: d1szjg1, d1szjr1
        complexed with nad, so4
  9. 259302Spinach (Spinacia oleracea) [TaxId:3562] [69769] (1 PDB entry)
  10. 259306Thermotoga maritima [TaxId:243274] [55353] (1 PDB entry)
  11. 259309Thermus aquaticus [TaxId:271] [55352] (1 PDB entry)
  12. 259314Trypanosoma brucei brucei, glycosome [TaxId:5702] [55356] (1 PDB entry)
  13. 259321Trypanosoma cruzi [TaxId:5693] [75483] (1 PDB entry)

More info for Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from d.81.1.1: GAPDH-like

Timeline for Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from d.81.1.1: GAPDH-like: