SCOPe 2.01: Fold d.81: FwdE/GAPDH domain-like

Lineage for Fold d.81: FwdE/GAPDH domain-like

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

Superfamilies:

1. d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

2. d.81.2: Serine metabolism enzymes domain [143548] (2 families)
   contains extra C-terminal beta-hairpin

3. d.81.3: FwdE-like [143555] (1 family)
   contains extra N-terminal and C-terminal structures

4. d.81.4: V-type ATPase subunit E-like [160527] (1 family)
   extra N-terminal helix and extra C-terminal helix form dimerisation subdomain

More info for Fold d.81: FwdE/GAPDH domain-like

Timeline for Fold d.81: FwdE/GAPDH domain-like:

• Fold d.81: FwdE/GAPDH domain-like first appeared (with stable ids) in SCOP 1.55, called Fold d.81: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  
• Fold d.81: FwdE/GAPDH domain-like appears in SCOP 1.75
  
• Fold d.81: FwdE/GAPDH domain-like appears in SCOPe 2.02
  
• Fold d.81: FwdE/GAPDH domain-like appears in the current release, SCOPe 2.08