SCOP 1.73: Superfamily d.265.1: Pseudouridine synthase

Lineage for Superfamily d.265.1: Pseudouridine synthase

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.265: Pseudouridine synthase [100877] (1 superfamily)
   consists of two alpha+beta subdomains with some similarity to the ferredoxin-like fold

4. Superfamily d.265.1: Pseudouridine synthase [55120] (4 families)
   the active site is the most conserved structural region of the superfamily and is located between the subdomains

Families:

1. d.265.1.1: Pseudouridine synthase I TruA [55121] (1 protein)

2. d.265.1.2: Pseudouridine synthase II TruB [69746] (1 protein)
   contains C-terminal PUA domain

3. d.265.1.3: Pseudouridine synthase RsuA/RluD [75459] (3 proteins)
   contains N-terminal alpha-L RNA-binding motif

4. d.265.1.4: tRNA pseudouridine synthase TruD [103021] (1 protein)
   natural circular permutation in the catalytic domain; insertion of the family-specific alpha+beta subdomain

More info for Superfamily d.265.1: Pseudouridine synthase

Timeline for Superfamily d.265.1: Pseudouridine synthase:

• Superfamily d.265.1: Pseudouridine synthase first appeared (with stable ids) in SCOP 1.55, called Superfamily d.58.35: Pseudouridine synthase I
  
• Superfamily d.265.1: Pseudouridine synthase appears in SCOP 1.71
  
• Superfamily d.265.1: Pseudouridine synthase appears in SCOP 1.75
  
• Superfamily d.265.1: Pseudouridine synthase appears in the current release, SCOPe 2.08