SCOPe 2.05: Family d.58.11.1: EF-G/eEF-2 domains III and V

Lineage for Family d.58.11.1: EF-G/eEF-2 domains III and V

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.58: Ferredoxin-like [54861] (59 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.11: EF-G C-terminal domain-like [54980] (4 families)

5. Family d.58.11.1: EF-G/eEF-2 domains III and V [54981] (2 proteins)
   domain III structure is lacking some of the superfamily characters and is often disordered in crystals

Proteins:

1. Elongation factor 2 (eEF-2) [82677] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82678] (13 PDB entries)
      Uniprot P32324

   2. Species Homo sapiens [TaxId:9606] [268003] (1 PDB entry)

2. Elongation factor G (EF-G) [54982] (2 species)
   domain III is seen in 1FNM but disordered in the most of other PDB entries

   1. Species Thermus thermophilus [TaxId:274] [54983] (9 PDB entries)

   2. Species Thermus thermophilus, EF-G-2 [TaxId:274] [143371] (2 PDB entries)
      Uniprot Q5SI76 371-447! Uniprot Q5SI76 563-658
      TTHA1498

More info for Family d.58.11.1: EF-G/eEF-2 domains III and V

Timeline for Family d.58.11.1: EF-G/eEF-2 domains III and V:

• Family d.58.11.1: EF-G/eEF-2 domains III and V first appeared (with stable ids) in SCOP 1.55, called Family d.58.11.1: Elongation factor G (EF-G), domains III and V
  
• Family d.58.11.1: EF-G/eEF-2 domains III and V appears in SCOPe 2.04
  
• Family d.58.11.1: EF-G/eEF-2 domains III and V appears in SCOPe 2.06
  
• Family d.58.11.1: EF-G/eEF-2 domains III and V appears in the current release, SCOPe 2.08