SCOPe 2.08: Protein: Splicesomal U1A protein

Lineage for Protein: Splicesomal U1A protein

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.58: Ferredoxin-like [54861] (62 superfamilies)
alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
Superfamily d.58.7: RNA-binding domain, RBD, aka RNA recognition motif (RRM) [54928] (6 families)
Family d.58.7.1: Canonical RBD [54929] (70 proteins)
Pfam PF00076
Pfam PF13893
Protein Splicesomal U1A protein [54932] (2 species)
duplication: contains two domains of this fold

Species:

Fruit fly (Drosophila melanogaster) [TaxId:7227] [160313] (3 PDB entries)
Uniprot P43332 1-104! Uniprot P43332 134-216
1. Domain for 2aym:
  - Domain d2ayma1: 2aym A:1-83 [146084]
    2nd RBD
2. Domain for 2b0g:
  - Domain d2b0ga1: 2b0g A:1-83 [146085]
    2nd RBD
3. Domain for 2k3k:
  - Domain d2k3ka1: 2k3k A:1-98 [148266]
    Other proteins in same PDB: d2k3ka2
    1st RBD
Human (Homo sapiens) [TaxId:9606] [54933] (54 PDB entries)
Uniprot P09012 1-97 ! Uniprot P09012 4-98 ! Uniprot P09012 1-98
1. Domain for 1aud:
  - Domain d1auda_: 1aud A: [39156]
    protein/RNA complex
2. Domain for 1cx0:
  - Domain d1cx0a_: 1cx0 A: [302300]
    automated match to d4pr6a_
    protein/RNA complex; complexed with mg
3. Domain for 1drz:
  - Domain d1drza_: 1drz A: [39159]
    domain 1, complex with a hepatitis delta virus ribozyme
    protein/RNA complex; complexed with mg, so4
4. Domains for 1dz5:
  1. Domain d1dz5a_: 1dz5 A: [39162]
    domain 1
    protein/RNA complex
  2. Domain d1dz5b_: 1dz5 B: [39163]
    domain 1
    protein/RNA complex
5. Domain for 1fht:
  - Domain d1fhta_: 1fht A: [39157]
    domain 1
6. Domains for 1m5k:
  1. Domain d1m5kc_: 1m5k C: [74509]
    domain 1, complex with a hairpin ribozyme
    protein/RNA complex; complexed with ca, cl
  2. Domain d1m5kf_: 1m5k F: [74510]
    domain 1, complex with a hairpin ribozyme
    protein/RNA complex; complexed with ca, cl
7. Domains for 1m5o:
  1. Domain d1m5oc_: 1m5o C: [78654]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca
  2. Domain d1m5of_: 1m5o F: [78655]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca
8. Domains for 1m5p:
  1. Domain d1m5pc_: 1m5p C: [78656]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca
  2. Domain d1m5pf_: 1m5p F: [78657]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca
9. Domains for 1m5v:
  1. Domain d1m5vc_: 1m5v C: [78662]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca, mpd
  2. Domain d1m5vf_: 1m5v F: [78663]
    domain 1, complex with a ribozyme
    protein/RNA complex; complexed with ca, mpd
10. Domains for 1nu4:
  1. Domain d1nu4a_: 1nu4 A: [80731]
    contains a pre-organized C-terminal helix
    complexed with mg, mla
  2. Domain d1nu4b_: 1nu4 B: [80732]
    contains a pre-organized C-terminal helix
    complexed with mg, mla
11. Domain for 1num:
  - Domain d1numa_: 1num A: [302786]
    automated match to d1dz5a_
    protein/RNA complex
12. Domains for 1oia:
  1. Domain d1oiaa_: 1oia A: [87051]
  2. Domain d1oiab_: 1oia B: [87052]
13. Domain for 1sj3:
  - Domain d1sj3p_: 1sj3 P: [105601]
    protein/RNA complex; complexed with mg
14. Domain for 1sj4:
  - Domain d1sj4p_: 1sj4 P: [105602]
    protein/RNA complex; mutant
15. Domain for 1sjf:
  - Domain d1sjfa_: 1sjf A: [105646]
    protein/RNA complex; complexed with nco
16. Domain for 1u6b:
  - Domain d1u6ba_: 1u6b A: [107703]
    protein/RNA complex; complexed with k, mg
17. Domains for 1urn:
  1. Domain d1urna_: 1urn A: [39153]
    domain 1
    protein/RNA complex; complexed with cl, gol; mutant
  2. Domain d1urnb_: 1urn B: [39154]
    domain 1
    protein/RNA complex; complexed with cl, gol; mutant
  3. Domain d1urnc_: 1urn C: [39155]
    domain 1
    protein/RNA complex; complexed with cl, gol; mutant
18. Domain for 1vbx:
  - Domain d1vbxa_: 1vbx A: [108489]
    protein/RNA complex
19. Domain for 1vby:
  - Domain d1vbya_: 1vby A: [108490]
    protein/RNA complex; complexed with mn, na
20. Domain for 1vbz:
  - Domain d1vbza_: 1vbz A: [108491]
    protein/RNA complex; complexed with ba
21. Domain for 1vc0:
  - Domain d1vc0a_: 1vc0 A: [108492]
    protein/RNA complex; complexed with sr
22. Domain for 1vc5:
  - Domain d1vc5a_: 1vc5 A: [108495]
    protein/RNA complex; complexed with na
23. Domain for 1vc6:
  - Domain d1vc6a_: 1vc6 A: [108496]
    protein/RNA complex; complexed with mg
24. Domain for 1zzn:
  - Domain d1zzna1: 1zzn A:4-98 [125912]
    automatically matched to d1auda_
    protein/RNA complex; complexed with k, mg
25. Domains for 2nz4:
  1. Domain d2nz4a_: 2nz4 A: [138833]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  2. Domain d2nz4b_: 2nz4 B: [138834]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  3. Domain d2nz4c_: 2nz4 C: [138835]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  4. Domain d2nz4d_: 2nz4 D: [138836]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
26. Domain for 2oih:
  - Domain d2oiha_: 2oih A: [139100]
    automated match to d1auda_
    protein/RNA complex; complexed with tl; mutant
27. Domain for 2oj3:
  - Domain d2oj3a_: 2oj3 A: [139101]
    automated match to d1auda_
    protein/RNA complex; complexed with nco, tl; mutant
28. Domain for 2u1a:
  - Domain d2u1aa_: 2u1a A: [39164]
    domain 2
29. Domain for 3bo2:
  - Domain d3bo2a1: 3bo2 A:6-97 [155439]
    automatically matched to d1auda_
    protein/RNA complex; complexed with mg
30. Domain for 3bo3:
  - Domain d3bo3a1: 3bo3 A:6-97 [155440]
    automatically matched to d1auda_
    protein/RNA complex; complexed with k, mg
31. Domain for 3bo4:
  - Domain d3bo4a1: 3bo4 A:6-97 [155441]
    automatically matched to d1auda_
    protein/RNA complex; complexed with k, mg
32. Domains for 3cul:
  1. Domain d3cula_: 3cul A: [156993]
    automated match to d1auda_
    protein/RNA complex; complexed with k, mg
  2. Domain d3culb_: 3cul B: [156994]
    automated match to d1auda_
    protein/RNA complex; complexed with k, mg
33. Domains for 3cun:
  1. Domain d3cuna_: 3cun A: [156997]
    automated match to d1dz5a_
    protein/RNA complex; complexed with co, k, mg
  2. Domain d3cunb_: 3cun B: [156998]
    automated match to d1dz5a_
    protein/RNA complex; complexed with co, k, mg
34. Domain for 3egz:
  - Domain d3egza_: 3egz A: [174934]
    automated match to d1auda_
    complexed with ctc, mg
35. Domains for 3g9c:
  1. Domain d3g9ca_: 3g9c A: [176436]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  2. Domain d3g9cb_: 3g9c B: [176437]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  3. Domain d3g9cc_: 3g9c C: [176438]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
  4. Domain d3g9cd_: 3g9c D: [176439]
    automated match to d1auda_
    protein/RNA complex; complexed with glp, mg
36. Domains for 3hhn:
  1. Domain d3hhnb_: 3hhn B: [177580]
    automated match to d1auda_
    protein/RNA complex; complexed with mg
  2. Domain d3hhnd_: 3hhn D: [177581]
    automated match to d1auda_
    protein/RNA complex; complexed with mg
37. Domain for 3irw:
  - Domain d3irwp_: 3irw P: [178587]
    automated match to d1auda_
    protein/RNA complex; complexed with c2e, iri, mg
38. Domains for 3l3c:
  1. Domain d3l3ca_: 3l3c A: [179902]
    automated match to d1urna_
    protein/RNA complex; complexed with g6p, mg
  2. Domain d3l3cb_: 3l3c B: [179903]
    automated match to d1urna_
    protein/RNA complex; complexed with g6p, mg
  3. Domain d3l3cc_: 3l3c C: [179904]
    automated match to d1urna_
    protein/RNA complex; complexed with g6p, mg
  4. Domain d3l3cd_: 3l3c D: [179905]
    automated match to d1urna_
    protein/RNA complex; complexed with g6p, mg
39. Domain for 3mum:
  - Domain d3mump_: 3mum P: [181569]
    automated match to d1auda_
    protein/RNA complex; complexed with c2e, mg; mutant
40. Domain for 3mxh:
  - Domain d3mxhp_: 3mxh P: [181676]
    automated match to d1auda_
    protein/RNA complex; complexed with c2e, mg
41. Domain for 3ucu:
  - Domain d3ucup_: 3ucu P: [186227]
    automated match to d1auda_
    protein/RNA complex; complexed with mg
42. Domain for 3ucz:
  - Domain d3uczp_: 3ucz P: [186229]
    automated match to d1auda_
    protein/RNA complex; complexed with mg
43. Domain for 3ud4:
  - Domain d3ud4p_: 3ud4 P: [186230]
    automated match to d1auda_
    protein/RNA complex; complexed with mg; mutant
44. Domain for 4pr6:
  - Domain d4pr6a1: 4pr6 A:4-96 [267208]
    Other proteins in same PDB: d4pr6a2
    domain 1, complex with a hepatitis delta virus ribozyme
    protein/RNA complex; complexed with mg
45. Domain for 4prf:
  - Domain d4prfa_: 4prf A: [267209]
    protein/RNA complex; complexed with sr
46. Domain for 4yb1:
  - Domain d4yb1p1: 4yb1 P:7-97 [271590]
    Other proteins in same PDB: d4yb1p2
    automated match to d4pr6a_
    protein/RNA complex; complexed with 4bw, mg; mutant
47. Domains for 5ddo:
  1. Domain d5ddoc_: 5ddo C: [280002]
    automated match to d1dz5a_
    protein/RNA complex
  2. Domain d5ddog_: 5ddo G: [280001]
    automated match to d1dz5a_
    protein/RNA complex
48. Domains for 5ddp:
  1. Domain d5ddpc_: 5ddp C: [280005]
    automated match to d1dz5a_
    protein/RNA complex; complexed with gln, mg, na
  2. Domain d5ddpd_: 5ddp D: [280006]
    automated match to d1dz5a_
    protein/RNA complex; complexed with gln, mg, na
49. Domains for 5ddq:
  1. Domain d5ddqc_: 5ddq C: [280007]
    automated match to d1dz5a_
    protein/RNA complex; complexed with gln, mg, mn, na
  2. Domain d5ddqd_: 5ddq D: [280003]
    automated match to d1dz5a_
    protein/RNA complex; complexed with gln, mg, mn, na
50. Domains for 5ddr:
  1. Domain d5ddrc_: 5ddr C: [280004]
    automated match to d1dz5a_
    protein/RNA complex; complexed with cs, gln, k, mg, na
  2. Domain d5ddrd_: 5ddr D: [280008]
    automated match to d1dz5a_
    protein/RNA complex; complexed with cs, gln, k, mg, na
51. Domains for 6sqn:
  1. Domain d6sqna_: 6sqn A: [385566]
    automated match to d1numa_
    mutant
  2. Domain d6sqnb_: 6sqn B: [385558]
    automated match to d1numa_
    mutant
  3. Domain d6sqnc_: 6sqn C: [385560]
    automated match to d1numa_
    mutant
52. Domain for 7aep:
  - Domain d7aepa_: 7aep A: [398183]
    automated match to d2u1aa_
53. Domain for 7d7v:
  - Domain d7d7vc_: 7d7v C: [394518]
    automated match to d1urna_
    complexed with gtp, mg, nad
54. Domain for 7lhx:
  - Domain d7lhxa_: 7lhx A: [402256]
    automated match to d1numa_
    complexed with act, bme, na; mutant

More info for Protein Splicesomal U1A protein from d.58.7.1: Canonical RBD

Timeline for Protein Splicesomal U1A protein from d.58.7.1: Canonical RBD:

Protein Splicesomal U1A protein from d.58.7.1: Canonical RBD first appeared (with stable ids) in SCOP 1.55
Protein Splicesomal U1A protein from d.58.7.1: Canonical RBD appears in SCOPe 2.07