SCOP 1.73: Superfamily d.58.4: Dimeric alpha+beta barrel

Lineage for Superfamily d.58.4: Dimeric alpha+beta barrel

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.58: Ferredoxin-like [54861] (55 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.4: Dimeric alpha+beta barrel [54909] (17 families)
   dimerizes through the beta-sheet; forms beta-sheet barrel, closed (n=8, S=12); dimers may assemble in higher oligomers

Families:

1. d.58.4.1: Muconalactone isomerase, MLI [54910] (1 protein)
   decamer: pentamer of dimers

2. d.58.4.2: Lrp/AsnC-like transcriptional regulator C-terminal domain [69733] (4 proteins)
   octamer: tetramer of dimers

3. d.58.4.3: Actinorhodin biosynthesis monooxygenase ActVa-Orf6 [82666] (1 protein)

4. d.58.4.4: Plant stress-induced protein [89927] (3 proteins)

5. d.58.4.5: PG130-like [102959] (4 proteins)
   subfamily of Pfam PF03992

6. d.58.4.6: Hypothetical protein YjcS [102962] (1 protein)

7. d.58.4.7: YciI-like [102965] (1 protein)
   structural similarity to MLI extends to the active site cavity location

8. d.58.4.8: Polyketide synthesis cyclase [110959] (1 protein)
   Pfam PF04673

9. d.58.4.9: DGPF domain (Pfam 04946) [110962] (1 protein)
   there is the putative active site cavity in the equivalent location location to the MLI and YciI active sites

10. d.58.4.10: Chlorite dismutase-like [110965] (2 proteins)
    Pfam PF06778; duplication: consists of two similar domains; forms a pentamer similar to the MLI decamer

11. d.58.4.11: PA3566-like [110970] (3 proteins)
    subfamily of Pfam PF03992

12. d.58.4.12: Hypothetical protein YdhR [117940] (1 protein)

13. d.58.4.13: NIPSNAP [117943] (2 proteins)
    Pfam PF07978

14. d.58.4.14: Dyp-type peroxidase-like [143265] (3 proteins)
    Pfam PF04261

15. d.58.4.15: EthD-like [143272] (1 protein)
    Pfam PF07110

16. d.58.4.16: Atu0297-like [143275] (1 protein)
    Pfam PF07045; DUF1330

17. d.58.4.17: SOR-like [143278] (1 protein)
    Pfam PF07682; duplication: consists of two similar domains

More info for Superfamily d.58.4: Dimeric alpha+beta barrel

Timeline for Superfamily d.58.4: Dimeric alpha+beta barrel:

• Superfamily d.58.4: Dimeric alpha+beta barrel first appeared (with stable ids) in SCOP 1.55, called Superfamily d.58.4: Muconalactone isomerase
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in SCOP 1.71
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in SCOP 1.75
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in the current release, SCOPe 2.08