SCOP 1.67: Superfamily d.58.4: Dimeric alpha+beta barrel

Lineage for Superfamily d.58.4: Dimeric alpha+beta barrel

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.58: Ferredoxin-like [54861] (48 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.4: Dimeric alpha+beta barrel [54909] (7 families)
   dimerizes through the beta-sheet; forms beta-sheet barrel, closed (n=8, S=12); dimers may assemble in higher oligomers

Families:

1. d.58.4.1: Muconalactone isomerase, MLI [54910] (1 protein)
   decamer: pentamer of dimers

2. d.58.4.2: Lrp/AsnC-like transcriptional regulator C-terminal domain [69733] (2 proteins)
   octamer: tetramer of dimers

3. d.58.4.3: Actinorhodin biosynthesis monooxygenase ActVa-Orf6 [82666] (1 protein)

4. d.58.4.4: Plant stress-induced protein [89927] (2 proteins)

5. d.58.4.5: Hypothetical protein TT1380 [102959] (1 protein)

6. d.58.4.6: Hypothetical protein YjcS [102962] (1 protein)

7. d.58.4.7: YciI-like [102965] (1 protein)
   structural similarity to MLI extends to the active site cavity location

More info for Superfamily d.58.4: Dimeric alpha+beta barrel

Timeline for Superfamily d.58.4: Dimeric alpha+beta barrel:

• Superfamily d.58.4: Dimeric alpha+beta barrel first appeared (with stable ids) in SCOP 1.55, called Superfamily d.58.4: Muconalactone isomerase
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in SCOP 1.65
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in SCOP 1.69
  
• Superfamily d.58.4: Dimeric alpha+beta barrel appears in the current release, SCOPe 2.08