Lineage for Fold d.58: Ferredoxin-like

  1. Root: SCOP 1.69
  2. 496776Class d: Alpha and beta proteins (a+b) [53931] (279 folds)
  3. 503917Fold d.58: Ferredoxin-like [54861] (49 superfamilies)
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

Superfamilies:

  1. 503918d.58.1: 4Fe-4S ferredoxins [54862] (5 families) (S)
  2. 504113d.58.2: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain [54893] (1 family) (S)
  3. 504191d.58.3: Protease propeptides/inhibitors [54897] (3 families) (S)
  4. 504226d.58.4: Dimeric alpha+beta barrel [54909] (11 families) (S)
    dimerizes through the beta-sheet; forms beta-sheet barrel, closed (n=8, S=12); dimers may assemble in higher oligomers
  5. 504343d.58.5: GlnB-like [54913] (4 families) (S)
    form timeric structures with the orthogonally packed beta-sheets
  6. 504418d.58.6: Nucleoside diphosphate kinases [54919] (1 family) (S)
  7. 504527d.58.7: RNA-binding domain, RBD [54928] (4 families) (S)
  8. 504721d.58.8: Viral DNA-binding domain [54957] (1 family) (S)
  9. 504757d.58.9: RuBisCO, large subunit, small (N-terminal) domain [54966] (1 family) (S)
    C-terminal domain is beta/alpha barrel
  10. 504867d.58.10: Acylphosphatase-like [54975] (1 family) (S)
  11. 504884d.58.11: EF-G C-terminal domain-like [54980] (3 families) (S)
  12. 504915d.58.12: eEF-1beta-like [54984] (1 family) (S)
  13. 504928d.58.13: Anticodon-binding domain of PheRS [54991] (1 family) (S)
  14. 504937d.58.14: Ribosomal protein S6 [54995] (1 family) (S)
  15. 504964d.58.15: Ribosomal protein S10 [54999] (1 family) (S)
  16. 504982d.58.16: PAP/Archaeal CCA-adding enzyme, C-terminal domain [55003] (2 families) (S)
  17. 505012d.58.17: HMA, heavy metal-associated domain [55008] (1 family) (S)
  18. 505075d.58.18: ACT-like [55021] (5 families) (S)
    regulatory domain linked to a wide range of metabolic enzymes
  19. 505109d.58.19: Bacterial exopeptidase dimerisation domain [55031] (1 family) (S)
  20. 505142d.58.20: NAD-binding domain of HMG-CoA reductase [55035] (1 family) (S)
  21. 505193d.58.21: Molybdenum cofactor biosynthesis protein C, MoaC [55040] (1 family) (S)
  22. 505199d.58.22: TRADD, N-terminal domain [55044] (1 family) (S)
  23. 505205d.58.23: Probable ACP-binding domain of malonyl-CoA ACP transacylase [55048] (1 family) (S)
  24. 505212d.58.24: CheY-binding domain of CheA [55052] (1 family) (S)
  25. 505231d.58.25: Killer toxin KP6 alpha-subunit [55056] (1 family) (S)
  26. 505236d.58.26: GHMP Kinase, C-terminal domain [55060] (7 families) (S)
    common fold is elaborated with additional secondary structures
  27. 505300d.58.27: Translational regulator protein regA [55064] (1 family) (S)
    common fold is elaborated with additional secondary structures
  28. 505306d.58.28: Peptide methionine sulfoxide reductase [55068] (1 family) (S)
    common fold is elaborated with additional secondary structures
  29. 505319d.58.29: Adenylyl and guanylyl cyclase catalytic domain [55073] (1 family) (S)
    common fold is elaborated with additional secondary structures
  30. 505347d.58.30: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK [55083] (1 family) (S)
    common fold is elaborated with additional secondary structures
  31. 505371d.58.31: Methyl-coenzyme M reductase subunits [55088] (2 families) (S)
    each of the three different subunits, alpha, beta and gamma, contains this fold decorated with additional secondary structures
  32. 505428d.58.32: FAD-linked oxidases, C-terminal domain [55103] (4 families) (S)
    duplication: contains two subdomains of this fold
  33. 505487d.58.33: Formylmethanofuran:tetrahydromethanopterin formyltransferase [55112] (1 family) (S)
    duplication: contains two subdomains of this fold
  34. 505525d.58.34: Formiminotransferase domain of formiminotransferase-cyclodeaminase. [55116] (1 family) (S)
    duplication: contains two subdomains of this fold
  35. 505533d.58.36: Sulfite reductase, domains 1 and 3 [55124] (1 family) (S)
    duplication: contains two subdomains of this fold
  36. 505561d.58.38: Urease metallochaperone UreE, C-terminal domain [69737] (1 family) (S)
  37. 505578d.58.39: Glutamyl tRNA-reductase catalytic, N-terminal domain [69742] (1 family) (S)
    common fold is elaborated with additional secondary structures
  38. 505583d.58.40: D-ribose-5-phosphate isomerase (RpiA), lid domain [75445] (1 family) (S)
  39. 505609d.58.41: SEA domain [82671] (1 family) (S)
  40. 505614d.58.42: N-utilization substance G protein NusG, N-terminal domain [82679] (1 family) (S)
  41. 505630d.58.43: Mechanosensitive channel protein MscS (YggB), C-terminal domain [82689] (1 family) (S)
    the last strand of the fold is flipped away and involved in oligomerisation
  42. 505641d.58.44: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains [82693] (1 family) (S)
    duplication: the N- and C-terminal halves of the whole proteins are structurally similar; each half contains two domains of this fold
  43. 505669d.58.46: eEF1-gamma domain [89942] (1 family) (S)
    elaborated with additional structures
  44. 505674d.58.47: Hypothetical protein VC0424 [89946] (1 family) (S)
  45. 505679d.58.48: MTH1187/YkoF-like [89957] (2 families) (S)
  46. 505703d.58.49: YajQ-like [89963] (1 family) (S)
    duplication: consists of two domains of this fold swapped with their N-terminal strands
  47. 505711d.58.50: Hypothetical protein TT1725 [103007] (1 family) (S)
  48. 505716d.58.51: eIF-2-alpha, C-terminal domain [110993] (1 family) (S)
  49. 505721d.58.52: Sporulation related repeat (SPOR, Pfam 05036) [110997] (1 family) (S)
    duplication: one domain contains two repeats of similar sequence and structure

More info for Fold d.58: Ferredoxin-like

Timeline for Fold d.58: Ferredoxin-like: