Class d: Alpha and beta proteins (a+b) [53931] (376 folds) |
Fold d.37: CBS-domain pair [54630] (1 superfamily) duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a |
Superfamily d.37.1: CBS-domain pair [54631] (1 family) |
Family d.37.1.1: CBS-domain pair [54632] (20 proteins) Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain |
Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species) contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals |
Chinese hamster (Cricetulus griseus) [TaxId:10029] [64260] (1 PDB entry) |
Domain d1jr1a4: 1jr1 A:113-232 [144358] Other proteins in same PDB: d1jr1a1, d1jr1b1 complexed with imp, k, moa |
Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry) |
Domain d1jcna4: 1jcn A:112-231 [144356] Other proteins in same PDB: d1jcna1, d1jcnb1 both CBS motifs are partly disordered in both chains, A and B |
Domain d1jcnb4: 1jcn B:112-231 [144357] Other proteins in same PDB: d1jcna1, d1jcnb1 both CBS motifs are partly disordered in both chains, A and B complexed with cpr |
Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries) |
Domain d1b3ob4: 1b3o B:112-231 [144354] Other proteins in same PDB: d1b3oa1, d1b3ob1 complexed with cpr, sae |
Domain d1nf7a4: 1nf7 A:112-231 [144359] Other proteins in same PDB: d1nf7a1, d1nf7b1 both CBS motifs are partly disordered in both chains, A and B |
Domain d1nf7b4: 1nf7 B:112-231 [144360] Other proteins in same PDB: d1nf7a1, d1nf7b1 both CBS motifs are partly disordered in both chains, A and B complexed with k, myd, rvp |
Domain d1nfba4: 1nfb A:112-231 [144361] Other proteins in same PDB: d1nfba1, d1nfbb1 both CBS motifs are partly disordered in both chains, A and B |
Domain d1nfbb4: 1nfb B:112-231 [144362] Other proteins in same PDB: d1nfba1, d1nfbb1 both CBS motifs are partly disordered in both chains, A and B complexed with cpr, nad |
Streptococcus pyogenes [TaxId:1314] [54635] (1 PDB entry) |
Domain d1zfja4: 1zfj A:95-220 [144739] Other proteins in same PDB: d1zfja1 complexed with imp |
Timeline for Protein Type II inosine monophosphate dehydrogenase CBS domains from d.37.1.1: CBS-domain pair: