Lineage for Family d.37.1.1: CBS-domain pair

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 858507Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 858508Superfamily d.37.1: CBS-domain pair [54631] (1 family) (S)
  5. 858509Family d.37.1.1: CBS-domain pair [54632] (20 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain

Proteins:

  1. 8585105'-AMP-activated protein kinase subunit gamma-1, AMPKg [160176] (1 species)
  2. 858518Chloride channel protein 5, ClC-5 [160174] (1 species)
  3. 858521Chloride channel protein, CBS tandem [143138] (1 species)
    contains additional structures between the two CBS repeats
  4. 858525Hypothetical protein MTH1622 [102897] (1 species)
  5. 858528Hypothetical protein Rv2626c [143142] (1 species)
  6. 858534Hypothetical protein Ta0289 [102899] (1 species)
    contains extra C-terminal zinc-finger domain
  7. 858540Hypothetical protein TM0892, CBS tandem [143136] (1 species)
  8. 858544Hypothetical protein TM0935 [102895] (1 species)
  9. 858547Hypothetical protein VC0737 [143140] (1 species)
    Putative acetoin utilization protein AcuB
  10. 858551Hypothetical protein YkuL [117881] (1 species)
  11. 858555Magnesium transporter MgtE [160163] (2 species)
    1. 858556Species Enterococcus faecalis [TaxId:1351] [160165] (1 PDB entry)
      Uniprot Q830V1 136-262
    2. 858558Species Thermus thermophilus [TaxId:274] [160164] (1 PDB entry)
      Uniprot Q5SMG8 132-275
  12. 858563Nuclear protein SNF4 [143134] (1 species)
    duplication: comprises four CBS repeats
  13. 858568Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
    1. 858569Species Chinese hamster (Cricetulus griseus) [TaxId:10029] [64260] (1 PDB entry)
    2. 858571Species Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)
    3. 858574Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)
    4. 858580Species Streptococcus pyogenes [TaxId:1314] [54635] (1 PDB entry)
  14. 858582Uncharacterized protein C1556.08c [160166] (1 species)
    consists of 4 CBS units
  15. 858586Uncharacterized protein NE2398 [160172] (1 species)
  16. 858592Uncharacterized protein PAE2072 [160178] (1 species)
    2 CBS domains = 1 Bateman domain; binds two adenosine nucleotides per subunit (one per one CBS repeat)
  17. 858600Uncharacterized protein PH0107 [160168] (1 species)
  18. 858604Uncharacterized protein PH1780 [160159] (1 species)
    duplication: comprises four CBS repeats
  19. 858608Uncharacterized protein SSO3205 [160170] (1 species)
    duplication: comprises four CBS repeats
  20. 858612Uncharacterized protein ST2348 [160161] (1 species)

More info for Family d.37.1.1: CBS-domain pair

Timeline for Family d.37.1.1: CBS-domain pair: