SCOPe 2.04: Protein: 4-hydroxyphenylpyruvate dioxygenase, HppD

Lineage for Protein: 4-hydroxyphenylpyruvate dioxygenase, HppD

Root: SCOPe 2.04
Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
beta-alpha-beta(3); 2 layers: alpha/beta
Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families)
Family d.32.1.3: Extradiol dioxygenases [54602] (4 proteins)
duplication: consists of 2 similar domains with 2 repeats in each
Similar to the Methylmalonyl-CoA epimerase dimer
Protein 4-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)

Species:

Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)
- Domains for 3isq:
  1. Domain d3isqa1: 3isq A:9-174 [211939]
    automated match to d1sqia1
    complexed with cl, co, edo, na
  2. Domain d3isqa2: 3isq A:175-384 [211940]
    automated match to d1sqia2
    complexed with cl, co, edo, na
Maize (Zea mays) [TaxId:4577] [110879] (1 PDB entry)
Uniprot O48604 29-423 # 85% sequence identity
- Domains for 1sp8:
  1. Domain d1sp8a1: 1sp8 A:36-207 [105868]
    complexed with fe2
  2. Domain d1sp8a2: 1sp8 A:208-431 [105869]
    complexed with fe2
  3. Domain d1sp8b1: 1sp8 B:36-207 [105870]
    complexed with fe2
  4. Domain d1sp8b2: 1sp8 B:208-431 [105871]
    complexed with fe2
  5. Domain d1sp8c1: 1sp8 C:37-207 [105872]
    complexed with fe2
  6. Domain d1sp8c2: 1sp8 C:208-431 [105873]
    complexed with fe2
  7. Domain d1sp8d1: 1sp8 D:36-207 [105874]
    complexed with fe2
  8. Domain d1sp8d2: 1sp8 D:208-431 [105875]
    complexed with fe2
Norway rat (Rattus norvegicus) [TaxId:10116] [256396] (1 PDB entry)
Uniprot P32755
- Domains for 1sqi:
  1. Domain d1sqia1: 1sqi A:8-174 [105914]
    complexed with 869, fe
  2. Domain d1sqia2: 1sqi A:175-366 [105915]
    complexed with 869, fe
  3. Domain d1sqib1: 1sqi B:8-174 [105916]
    complexed with 869, fe
  4. Domain d1sqib2: 1sqi B:175-366 [105917]
    complexed with 869, fe
Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)
- Domains for 1cjx:
  1. Domain d1cjxa1: 1cjx A:4-153 [38516]
    complexed with act, emc, fe2
  2. Domain d1cjxa2: 1cjx A:154-356 [38517]
    complexed with act, emc, fe2
  3. Domain d1cjxb1: 1cjx B:4-153 [38518]
    complexed with act, emc, fe2
  4. Domain d1cjxb2: 1cjx B:154-356 [38519]
    complexed with act, emc, fe2
  5. Domain d1cjxc1: 1cjx C:4-153 [38520]
    complexed with act, emc, fe2
  6. Domain d1cjxc2: 1cjx C:154-356 [38521]
    complexed with act, emc, fe2
  7. Domain d1cjxd1: 1cjx D:4-153 [38522]
    complexed with act, emc, fe2
  8. Domain d1cjxd2: 1cjx D:154-356 [38523]
    complexed with act, emc, fe2
Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)
Uniprot Q53586
- Domains for 1t47:
  1. Domain d1t47a1: 1t47 A:16-178 [106398]
    complexed with fe2, ntd
  2. Domain d1t47a2: 1t47 A:179-377 [106399]
    complexed with fe2, ntd
  3. Domain d1t47b1: 1t47 B:16-178 [106400]
    complexed with fe2, ntd
  4. Domain d1t47b2: 1t47 B:179-377 [106401]
    complexed with fe2, ntd
Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (4 PDB entries)
Uniprot P93836 33-428 ! Uniprot P93836 63-459
1. Domains for 1sp9:
  1. Domain d1sp9a1: 1sp9 A:33-232 [238534]
    complexed with fe2
  2. Domain d1sp9a2: 1sp9 A:233-428 [238535]
    complexed with fe2
  3. Domain d1sp9b1: 1sp9 B:33-193 [238536]
    automated match to d1tg5a1
    complexed with fe2
  4. Domain d1sp9b2: 1sp9 B:202-437 [238537]
    automated match to d1tg5a2
    complexed with fe2
2. Domains for 1sqd:
  1. Domain d1sqda1: 1sqd A:14-195 [105906]
    complexed with fe
  2. Domain d1sqda2: 1sqd A:196-410 [105907]
    complexed with fe
3. Domains for 1tfz:
  1. Domain d1tfza1: 1tfz A:15-195 [106886]
    complexed with 869, fe
  2. Domain d1tfza2: 1tfz A:196-408 [106887]
    complexed with 869, fe
4. Domains for 1tg5:
  1. Domain d1tg5a1: 1tg5 A:14-195 [106890]
    complexed with 645, fe2
  2. Domain d1tg5a2: 1tg5 A:196-410 [106891]
    complexed with 645, fe2

More info for Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases

Timeline for Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases:

Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases first appeared (with stable ids) in SCOP 1.55
Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases appears in SCOPe 2.03
Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases appears in SCOPe 2.05
Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases appears in the current release, SCOPe 2.08