SCOP 1.73: Family d.32.1.3: Extradiol dioxygenases

Lineage for Family d.32.1.3: Extradiol dioxygenases

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
   beta-alpha-beta(3); 2 layers: alpha/beta

4. Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (10 families)

5. Family d.32.1.3: Extradiol dioxygenases [54602] (4 proteins)
   duplication: consists of 2 similar domains with 2 repeats in each
   Similar to the Methylmalonyl-CoA epimerase dimer

Proteins:

1. 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603] (2 species)

   1. Species Burkholderia cepacia, formerly Pseudomonas cepacia [TaxId:292] [54605] (6 PDB entries)

   2. Species Pseudomonas sp. [TaxId:306] [54604] (10 PDB entries)

2. 4-hydroxyphenylpyruvate dioxygenase, HppD [54608] (5 species)

   1. Species Corn (Zea mays) [TaxId:4577] [110879] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)

   3. Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [110877] (4 PDB entries)

   4. Species Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)

   5. Species Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)

3. Catechol 2,3-dioxygenase (metapyrocatechase) [54606] (1 species)

   • Species Pseudomonas putida, mt2 [TaxId:303] [54607] (1 PDB entry)

4. Homoprotocatechuate 2,3-dioxygenase [89886] (2 species)

   1. Species Arthrobacter globiformis [TaxId:1665] [89887] (3 PDB entries)

   2. Species Brevibacterium fuscum [TaxId:47914] [89888] (5 PDB entries)

More info for Family d.32.1.3: Extradiol dioxygenases

Timeline for Family d.32.1.3: Extradiol dioxygenases:

• Family d.32.1.3: Extradiol dioxygenases first appeared (with stable ids) in SCOP 1.55
  
• Family d.32.1.3: Extradiol dioxygenases appears in SCOP 1.71
  
• Family d.32.1.3: Extradiol dioxygenases appears in SCOP 1.75
  
• Family d.32.1.3: Extradiol dioxygenases appears in the current release, SCOPe 2.08