SCOP 1.71: Protein: Bleomycin resistance protein, BRP

Lineage for Protein: Bleomycin resistance protein, BRP

Root: SCOP 1.71
Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
beta-alpha-beta(3); 2 layers: alpha/beta
Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (9 families)

Family d.32.1.2: Antibiotic resistance proteins [54598] (5 proteins)
duplication: consists of two clear structural repeats each having this fold
subunit fold and dimeric assembly are similar to those of glyoxalase

Protein Bleomycin resistance protein, BRP [54599] (3 species)
Active as dimer

Species:

Klebsiella pneumoniae [TaxId:573] [64256] (4 PDB entries)
the transposon tn5-encoding bleomycin-binding protein, BlmT
1. Domains for 1ecs:
  1. Domain d1ecsa_: 1ecs A: [59407]
  2. Domain d1ecsb_: 1ecs B: [59408]
    complexed with ca, pg4
2. Domains for 1ewj:
  1. Domain d1ewja_: 1ewj A: [59526]
  2. Domain d1ewjb_: 1ewj B: [59527]
  3. Domain d1ewjc_: 1ewj C: [59528]
  4. Domain d1ewjd_: 1ewj D: [59529]
  5. Domain d1ewje_: 1ewj E: [59530]
  6. Domain d1ewjf_: 1ewj F: [59531]
  7. Domain d1ewjg_: 1ewj G: [59532]
  8. Domain d1ewjh_: 1ewj H: [59533]
    complexed with blm
3. Domains for 1mh6:
  1. Domain d1mh6a_: 1mh6 A: [79116]
  2. Domain d1mh6b_: 1mh6 B: [79117]
4. Domains for 1niq:
  1. Domain d1niqb_: 1niq B: [91891]
  2. Domain d1niqc_: 1niq C: [91892]
    complexed with blm, cu
Streptoalloteichus hindustanus [TaxId:2017] [54601] (2 PDB entries)
1. Domain for 1byl:
  - Domain d1byla_: 1byl A: [38495]
2. Domains for 1xrk:
  1. Domain d1xrka_: 1xrk A: [115881]
  2. Domain d1xrkb_: 1xrk B: [115882]
    complexed with blm, so4; mutant
Streptomyces verticillus [TaxId:29309] [54600] (3 PDB entries)
1. Domains for 1jie:
  1. Domain d1jiea_: 1jie A: [66736]
  2. Domain d1jieb_: 1jie B: [66737]
    complexed with blm
2. Domains for 1jif:
  1. Domain d1jifa_: 1jif A: [66738]
  2. Domain d1jifb_: 1jif B: [66739]
    complexed with blm, cl, cu
3. Domain for 1qto:
  - Domain d1qtoa_: 1qto A: [38494]

More info for Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins

Timeline for Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins:

Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins first appeared (with stable ids) in SCOP 1.55, called Protein Bleomycin resistance protein, BRP from d.32.1.2: Bleomycin resistance protein, BRP
Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins appears in SCOP 1.69
Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins appears in SCOP 1.73
Protein Bleomycin resistance protein, BRP from d.32.1.2: Antibiotic resistance proteins appears in the current release, SCOPe 2.08