Lineage for Family d.32.1.2: Antibiotic resistance proteins

  1. Root: SCOP 1.71
  2. 595667Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
  3. 601425Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 601426Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (9 families) (S)
  5. 601455Family d.32.1.2: Antibiotic resistance proteins [54598] (5 proteins)
    duplication: consists of two clear structural repeats each having this fold
    subunit fold and dimeric assembly are similar to those of glyoxalase

Proteins:

  1. 601456Bleomycin resistance protein, BRP [54599] (3 species)
    Active as dimer
    1. 601457Species Klebsiella pneumoniae [TaxId:573] [64256] (4 PDB entries)
      the transposon tn5-encoding bleomycin-binding protein, BlmT
    2. 601472Species Streptoalloteichus hindustanus [TaxId:2017] [54601] (2 PDB entries)
    3. 601476Species Streptomyces verticillus [TaxId:29309] [54600] (3 PDB entries)
  2. 601482Fosfomycin resistance protein A (FosA) [82630] (2 species)
    1. 601483Species Pseudomonas aeruginosa [TaxId:287] [82631] (5 PDB entries)
    2. 601494Species Serratia marcescens [TaxId:615] [102871] (1 PDB entry)
      gene from transposon tn2921
  3. 601501Fosfomycin resistance protein FosX [102872] (1 species)
  4. 601505Hypothetical protein BC3580 [117870] (1 species)
  5. 601509Mitomycin resistance protein D, MRD [75394] (1 species)

More info for Family d.32.1.2: Antibiotic resistance proteins

Timeline for Family d.32.1.2: Antibiotic resistance proteins: