Lineage for Family d.32.1.2: Antibiotic resistance proteins

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2166686Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 2166687Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 2166741Family d.32.1.2: Antibiotic resistance proteins [54598] (8 protein domains)
    duplication: consists of two clear structural repeats each having this fold
    subunit fold and dimeric assembly are similar to those of glyoxalase

Protein Domains:

  1. 2166742Bleomycin resistance protein, BRP [54599] (3 species)
    Active as dimer
    1. 2166743Species Klebsiella pneumoniae [TaxId:573] [64256] (4 PDB entries)
      the transposon tn5-encoding bleomycin-binding protein, BlmT
    2. 2166758Species Streptoalloteichus hindustanus [TaxId:2017] [54601] (2 PDB entries)
      Uniprot P17493
    3. 2166762Species Streptomyces verticillus [TaxId:29309] [54600] (3 PDB entries)
  2. 2166768Fosfomycin resistance protein A (FosA) [82630] (2 species)
    1. 2166769Species Pseudomonas aeruginosa [TaxId:287] [82631] (5 PDB entries)
    2. 2166780Species Serratia marcescens [TaxId:615] [102871] (1 PDB entry)
      gene from transposon tn2921
  3. 2166787Fosfomycin resistance protein FosX [102872] (1 species)
  4. 2166791Hypotheical protein SP0731 [143127] (1 species)
  5. 2166794Hypothetical protein BC3580 [117870] (1 species)
  6. 2166798Mitomycin resistance protein D, MRD [75394] (1 species)
  7. 2166802Uncharacterized protein Atu1953 [160145] (1 species)
  8. 2166806automated matches [190190] (5 species)
    not a true protein
    1. 2166807Species Listeria monocytogenes [TaxId:169963] [187361] (5 PDB entries)
    2. 2166834Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [187844] (1 PDB entry)
    3. 2166836Species Streptoalloteichus hindustanus [TaxId:2017] [188784] (1 PDB entry)
    4. 2166839Species Streptomyces caespitosus [TaxId:53502] [186930] (2 PDB entries)
    5. 2166844Species Streptomyces flavoviridis [TaxId:66889] [193979] (2 PDB entries)

More info for Family d.32.1.2: Antibiotic resistance proteins

Timeline for Family d.32.1.2: Antibiotic resistance proteins: