SCOPe 2.01: Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

Lineage for Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
   beta-alpha-beta(3); 2 layers: alpha/beta

4. Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families)

Families:

1. d.32.1.1: Glyoxalase I (lactoylglutathione lyase) [54594] (2 proteins)
   duplication: consists of two clear structural repeats each having this fold

2. d.32.1.2: Antibiotic resistance proteins [54598] (8 proteins)
   duplication: consists of two clear structural repeats each having this fold
   subunit fold and dimeric assembly are similar to those of glyoxalase

3. d.32.1.3: Extradiol dioxygenases [54602] (4 proteins)
   duplication: consists of 2 similar domains with 2 repeats in each
   Similar to the Methylmalonyl-CoA epimerase dimer

4. d.32.1.4: Methylmalonyl-CoA epimerase [64257] (1 protein)
   Different association of repeats but a similar dimeric structure to the glyoxalase dimer

5. d.32.1.5: Hypothetical protein YecM (EC4020) [75396] (1 protein)
   Similar subunit fold is to methylmalonyl-CoA epimerase

6. d.32.1.6: Hypothetical protein BC1747 [110880] (1 protein)
   subunit fold and dimeric assembly are similar to those of glyoxalase

7. d.32.1.7: 3-demethylubiquinone-9 3-methyltransferase [110883] (4 proteins)
   Pfam PF06983; both variants of dimeric assembly are observed in the family (domain swapping)

8. d.32.1.8: Hypothetical protein YycE [110888] (1 protein)
   subunit fold and dimeric assembly are similar to those of glyoxalase

9. d.32.1.9: Hypothetical protein At5g48480 [117876] (2 proteins)
   subunit fold and dimeric assembly are similar to those of glyoxalase

10. d.32.1.10: BC1024-like [143129] (1 protein)
    duplication: consists of 2 similar domains with 2 repeats in each; similar to the glyoxalase dimer

11. d.32.1.0: automated matches [191344] (1 protein)
    not a true family

More info for Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

Timeline for Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase:

• Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase first appeared (with stable ids) in SCOP 1.55
  
• Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase appears in SCOP 1.75
  
• Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase appears in SCOPe 2.02
  
• Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase appears in the current release, SCOPe 2.08